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《Carcinogenesis,Teratogenesis and Mutagenesis》 1991-03
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INHIBITORY EFFECTS OF THREE CHINESE ANTI-SENILITY TONICS ON THE SOS RESPONSE IN E. COLI AND THEIR INFLUENCE ON THE LIFE-SPAN OF C. ELEGANS

Chen Zhongfu, Gu Huijue, Wang Linhua, Pan Xingshi Institute of Genetics. Fudan University, Shanghai Institute for Pediatric Research Acknowledgement : The nematode strain DH26 used in tins work was provided by the Caeno-rhabditis Genetics Center, which is funded by the NIH National Center for Research Resources (NCRR).  
The experiments show that Haijingjian, Qingchunbao and Cixi Yshoubao inhibit the SOS responses induced by Mitomycin C in E. coli strain PQ35. These Chinese anti-senility tonics can also prolong the mean life-span of nematode C. elegans, The correlation between these two phenomena is discussed in this papers.
【Fund】: 国家自然科学基金(3880850)
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