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《CARCINOGENESIS, TERATOGENESIS AND MUTAGENESIS》 2000-04
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ANTIOXIDATIVE ABILITY OF CARBOXYETHYLGERMANIUM (GE-132) ON THE AFB\-1 INDUCED HEPATOCARCINOGENESIS IN RAT

HOU Hua xin, LI Dan rong, TU Wen sheng, et al (Guangxi Medical University, Nanning\ 530021, China)  
Results: This paper reports that Ge-132 possessed the remarkable resistance effects on AFB\-1 \{reducing\} Superoxide Dismutase (SOD) activity in vivo during AFB\-1-induced hepatocarcinogenesis for short term model experiments. The SOD activity can be affected by the time and the dosage of Ge-132 intaken. Conclusion: The results indicated that antioxidative ability of Ge-132 is relate to its anticarciogenicity. Ge-132 can be used as a safe and effective chemoprevention agent.
【Fund】: 广西区卫生厅青年基金!资助项目 (青 92 0 7)
【CateGory Index】: R735.7
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