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《Carcinogenesis,Teratogenesis and Mutagenesis》 2001-01
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STUDY ON THE ANTIMUTAGENICITY OF SEAWEED POLYSACCHARIDES

XIANG Hua\+1,ZHAO Jian-zhong\+2, BO Lin\+2 (1.Hygiene and Anti-epidemic Station of Hangzhou, Hangzhou\ 310006, China; 2.Department of Cytobiology, College of Biological Sciences, Zhejiang University, Hangzhou 310009, China)  
Purpose and Methods: In order to characterize the antimutagenic effect of seaweed polysaccharides(SP), the mouse bone marrow micronucleus test and mouse sperm malformation test were conducted. Results: The results showed that the frequencies of micronucleus and abnormal sperms induced by cyclophosphamide(CP) were reduced significantly by SP(P0,01). Conclusion: It is suggested that SP can significantly inhibit the mutagenesis of germ cells and stomatic cells induced by CP.
【CateGory Index】: R285
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