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THE MUTAGENICITY STUDY OF CHLORINE DIOXIDE USING MICRONUCLEUS TEST IN VICIA FABA ROOT TIP CELLS

JIANG Hui quan, NI Xiao ping, KOU Yu (Center of Disease Prevention and Control in Hangzhou, Hangzhou 310006, China)  
Purpose and Methods: The mutagenecity of two batches of chlorine dioxide(ClO\-2) were studide using micronucleus test in Vicia faba root tip cells. Results: The frequencies of micronucleus of two kinds of ClO\-2 were (17.91±4.80)‰ and (17.5±3.12)‰ respectively when the diluent multiple of ClO\-2 was at 1:100. Comparing with the tap water group, the differences(χ\+2\-A=30.57, χ\+2\-B=29.60 P0.01) was statistically \{significant\} and the dose effect relationship ws clear. Conclusion: Clorine dioxide has mutagenicity. We should pay attention to safety of its apllication in food and water.
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