Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Carcinogenesis,Teratogenesis and Mutagenesis》 2004-06
Add to Favorite Get Latest Update

Study on Vitro Anti-respiratory Virus Infection Effect of Organogermanium Poly-derivatives

TIAN Li-li, ZHANG Gui-ying, WANG Bao-gui, et al (College of Preventive Medicine, Jilin University, Changchun 130021, China)  
BACKGROUND AIM: To study the cytotoxicity on normal cell and antiviral effect of organogermaniurn Poly-derivatives on breath virus, and provide a basis to clinical application. MATERIAL AND METHODS: The cytoxicity on FL was studied with the method of MTT. Establish the model of breath viral infected in vitro and observe protective function of organogermaniurn poly-derivatives on infected cells by methods of CPE and MTT. To study the antiviral effect of organogermanium poly-derivatives by changing time, way and concentration of giving medicine. RESULTS: The quantity of surviving cells was more than virus infecting group. When the dosage reached 160.00 μg/ml, inhibiting RSV effect of organogermanium poly-derivatives was higher than the ribavirin group.In the group that the Hela cells were infected by RSV first then treated with organogermanium poly-derivatives, the quantity of alive cell was more than the ribavirin group. CONCLUSION: organogermanium poly-derivatives is a kind of medicine that has definite antiviral function.
【CateGory Index】: R285
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 2 Hits
1 ZHANG Xiao-chun1,ZHOU Shu-hua1,ZOU Li-min2,CHEN Cai-fen1(1.School of Medicine,Jinggangshan University;2.School of Physical Education,Jinggangshan University,Ji′an 343000,China);The role of organic germanium in medicine[J];Journal of Jinggangshan University;2009-05
2 ZHANG Xiao-chun1,ZHOU Shu-hua1,LIU Chun-hua2 1.The College of Medicine of Jinggangshan University,Ji'an 343009; 2.Jiangxi University of Traditional Chinese Medicine,Nanchang 330006;Effects of Caffeic Acid Ge on Mice Bearing H22 immune organs[J];Journal of Jiangxi University of Traditional Chinese Medicine;2011-06
【Citations】
Chinese Journal Full-text Database 2 Hits
1 ZHANG Yu, WANG Bao - gui, ZHANG Gui - ying, et al ( 1. College of Preventive Medicine, Jilin University, Changchun 130021, China; 2. Leader Ward of The First Hospital, Jilin University , Changchun 130021, China);Study of Anti-tumor and Mechanism of Organogermanium Poly-derivatinmves[J];Carcinogenesis,Teratogenesis and Mutagenesis;2004-01
2 Niu Jianwei, Xie Ping Henan Institute of Pharmaceutical Industry(Kaifeng 475003);Study on Effects of Saccharum Germanium of Glossy Ganoderma on Immunity and Antitumor[J];CHINESE JOURNAL OF BIOCHEMICAL PHARMACEUTICS;2000-04
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 Lv Chaotian et al.(Bengbu College,Bengbu 233030,China);Progress of Researches on Main Active Substances and Pharmacology of Ganoderma Lucidum[J];Anhui Agricultural Science Bulletin;2011-01
2 LI Sheng-he et al(College of Animal Science and Technology,North-Western Agriculture and Forestry University,Yangling,Shanxi 712100);Effect of Higher Boron on Post Embryonic Development of Thymus in Gu-shi Chicken[J];Journal of Anhui Agricultural Sciences;2005-11
3 ZHANG Chen,LI Chun-ru,FAN Mei-zhen,DU Yu(Anhui Provincial Key Laboratory for Microbial Control,Anhui Agricultural University,Hefei 230036);Screening for a vanadium-enriched yeast and primary optimization of cultivation condition[J];Journal of Anhui Agricultural University;2006-02
4 SUN Su\|ling\ YU Xiao\|dan (Anhui Technical Teachers College,Fengyang\ 233100);Effect of Aletic Acid Lead on the Sperm Formation of Male Rat[J];Journal of Anhui Agrotechnical;2001-04
5 ZHENG Yi-mei ,WU Yan-zhu,JI Bing-long (1. Engineering and Techniology Department, Anhui Technical Teachers College, Fengyang 233100, China; 2. Animal Husbandy & Veterinary Medicine Station of Bengbu Suburbs, Bengbu 233000, China);Analysis the Content of Chromium in Common Grains[J];Journal of Anhui Technical Teachers College;2003-04
6 ZHOU Jin-xing,WANG Jue,JIN Guang-ming,GU You-fang,SHANG Chang-fa,LI Sheng-he,CHEN Hui-liang (Animal Science College,Anhui Science and Technology University,Fengyang 233100,China);Effect of Vanadium on Growth and Development of Spleen in SD Rats[J];Journal of Anhui Science and Technology University;2008-03
7 JIN Ri-guang LU Kun (College of Materials Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, China);The JRG-Fourth statistics scale on the distribution law of biopolymer element active centers in Chinese medicines(Ⅰ): Relationship between the distribution law of life power elements of anticancer Chinese medicines and the sub-cluster parame[J];Journal of Beijing University of Chemical Technology;2002-06
8 JIN Ri-guang L U·· Kun (College of Materials Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, China);The JRG-Fourth statistics scale on the distribution law of biopolymer element active centers in Chinese medicines(Ⅱ) The relationship between the distribution law of power elements of cardiovascular Chinese medicines and the sub-cluster para[J];Journal of Beijing University of Chemical Technology;2003-01
9 JIN Ri-guang MU Xue-yan (College of Materials Science and Engineering, Beijing University of Chemical Technology; Beijing Sub-cluster Life Power Technology Institute, Beijing 100029, China);The JRG-Fourth statistics scale on the distribution law of biopolymer element active centers in Chinese medicines(Ⅳ):──Relationship between the Yin-Yang attributes and oxidation potential of hydrated complexion lying in the bioactive centers[J];Journal of Beijing University of Chemical Technology;2003-05
10 Wang Xiaolan\ Gu Tiancheng(Departement of Chemical Engineering,Beijing Institute of Light Industry,Beijing 100037);OPTIMAL CONDITION FOR THE SYNTHESIS ORGANIC FORM OF Cr BY BREWER'S YEAST[J];JOURNAL OF BEIJING INSTITUTE OF LIGHT INDUSRY;1998-02
China Proceedings of conference Full-text Database 4 Hits
1 Xujie Yang Lude Lu Xin Wang Chemistry and Engineering School,Nanjing University of Science and Technology Nanjing,210094;NMR study and crystal structure of solid-state room-temperature reaction[A];[C];2004
2 Liu Yaqiong~1 Zhu Hongda~2 Xie Qing~1 Wang Naifen~1 Liu Haitao~3 Liu Husheng~1 Wang Jingyu~(1*)(1 Public Health College,Peking University,Beijing 100083,China)(2 Institute of Radiation Medicine,Chinese Academy of Medical Science,Tianjin 300192,China)(3 Beijing Kechuang Haiguang Instrument Co.Ltd,Beijing 100016,China);Determination of 8 Micro-quantity Elements in Liver for Chinese Adult Man by ICP-AES[A];[C];2007
3 Wang Dongfeng, Zhou Xiaolin, Wang Changhong, Sun Jipen, Zhou Yibing College of Food Science and Engineering, Ocean University of China, Qingdao 266003, China;REE Binding Tea Polysaccharides and It's Some Bioactivities[A];[C];2006
4 LIU Husheng~1 ZHU Hongda~2 WANG Xiaoyan~1 WANG Naifen~1 WANG Jingyu~(1*) 1、Public Health College,Peking University,Beijing 100083,China; 2、Institute of Radiahion Medicine,Chinese Academy of Medical Science,Tianjing 300192,China;Determination of 15 Micro-quantity Rare Earth Elements in Lung,Liver and Kidney for Chinese Adult Man by ICP-MS[A];[C];2007
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 HOU Hua xin, LI Dan rong, TU Wen sheng, et al (Guangxi Medical University, Nanning\ 530021, China);ANTIOXIDATIVE ABILITY OF CARBOXYETHYLGERMANIUM (GE-132) ON THE AFB\-1 INDUCED HEPATOCARCINOGENESIS IN RAT[J];CARCINOGENESIS, TERATOGENESIS AND MUTAGENESIS;2000-04
2 ZHANG Yu, WANG Bao - gui, ZHANG Gui - ying, et al ( 1. College of Preventive Medicine, Jilin University, Changchun 130021, China; 2. Leader Ward of The First Hospital, Jilin University , Changchun 130021, China);Study of Anti-tumor and Mechanism of Organogermanium Poly-derivatinmves[J];Carcinogenesis,Teratogenesis and Mutagenesis;2004-01
3 YANG Guo tian 1,CHANG Ya ping 1* ,WU Jiang feng 2,WANG En bo 3 (1. Dept.of Immunology,School of Basic Medical Sciences,Jilin University, Changchun 130021,China;2. Dept.of Anatomy, College of Medical Sciences,Sanxia University; 3. School of Chemistry,Northeast Normal Univesity) [;Investigation of the Antitumor Effect of (glyH)_3GeMo_(12)O_(40)·3H_2O on Tumor Cell in Vivo and Antitumor Mechanism[J];Journal of Jilin University of (Medicine Edition);2003-05
4 YANG Guo tian 1,CHANG Ya ping 1* ,CHEN Qiang △,HAN Zheng bo 2,WANG En bo 2 (1. Dept.of Immunology,School of Basic Medical Sciences,Jilin University, Changchun 130021, China;2. Institute of Polds, School of Chemistry,Northeast Normal University);Inhibitory Effect of (glyH)_3GeMo_(12)O_(40)·3H_2O on Tumor Growth in vitro[J];Journal of Jilin University of (Medicine Edition);2003-06
5 LU Chuan-Xin,ZHANG Shu-Gong,NI Jia-Zuan(Changchun Institute of Applied Chemistry,Academia Sinica,Changchun,130022)NIE Yu-Xiu,CHEN Yu-Lan (Norman Bethune University of Medical Science,Changchun);Sythnesis and Effect of p-(Diethylamino)phenylgermanium Sesquioxide on Human Breastcarcinoma Cells in Vitro[J];Chemical Research In Chinese Universities;1992-12
6 LIU Jie 1, ZHANG Qian Ling 1, WANG Li Jun 2 WANG En Bo 3, HUANG Jin Wang 1, JI Liang Nian 1  [WT5”BX](1. State Key Laboratory of Ultrafast Laser Spectroscopy, Department of Chemistry, Zhongshan University, Guangzhou 510275, China;Synthesis, Properties and Antiviral Activity of Keggin Molybdogemnium Heteropoly Blues[J];Chemical Research In Chinese Universities;2000-12
7 CHEN Jian-Xin~(1),CHEN Li~(1),ZHAI Yu-Ping~(2),SHI Yin~2,SUN Li-Juan~(1*)(1.State Key Laboratory of Elemento-Organic Chemistry,2.Department of Chemistry,College of Chemistry,Nankai University,Tianjin 300071,China);Syntheses of Novel Organogermanium Compounds Containing α-Amino Acid and Studies on the Antitumor Activity[J];Chemical Journal of Chinese Universities;2006-08
8 LI Guo Qiang TANG Xu Li (Department of Applied Chemistry,Qingdao Science & Technology University, No.53 Zhengzhoulu,Qingdao,Shandong 266042,P.R.China);Investigation of Germanium in Seutellaria Baiealensis Gorgi by Spectrophotometry[J];Chinese Journal of Spectroscopy Laboratory;2002-05
9 ZHONG Hui Min YUAN Jin LI Feng Qi (Department of Applied Chemistry,Qingdao Science & Technology University, No.53 Zhengzhoulu,Qingdao,Shandong 266042,P.R.China);Spectrophotometric Determination of Germanium in Panax Genseng C.A. Mey[J];Chinese Journal of Spectroscopy Laboratory;2002-06
10 Zhang Guilin; Lu Sulin; Zhong Hengliang (Department of Pharmacology, Guiyang Medical College, Guiyang 550004);Experimental Study on the Effects of Organic Germanium (Ge-201) on Nonspecific Immunity of Mice[J];TRACE ELEMENTS SCIENCE;1997-09
【Secondary References】
Chinese Journal Full-text Database 6 Hits
1 TIAN Wei et al(Institute of Pharmacy of Jiangxi Traditional Chinese Medicine College,Nanchang,Jiangxi 330004);The Application of Germatranes of Hydroxyl Substituted Cinnamic Acid Compounds in the Diet of Gallus domesticus Brisson[J];Journal of Anhui Agricultural Sciences;2012-08
2 XIONG Zheng-ying,YANG Hua(The Gymnastics Institute,Shaanxi Normal University,Xi'an 710062,China);Biological function of trace element germanium and movement ability[J];Journal of Qinghai Normal University(Natural Science Edition);2008-04
3 Wang Ai-ying,Li Jun(College of Food Science and Technology,Hebei Normal University of Science and Technology,Qinhuangdao 066600,China);Determination of Extracellular and Intracellular pH of Saprophytic Yeast Suspension Under Supercritical Carbon Dioxide Treatment[J];Food and Fermentation Industries;2011-09
4 WANG Tao1,LI Wen1,CHEN Hong-wei1,YU Zeng-liang2(1.School of Food Engineering,Xuzhou Institute of Technology,Xuzhou 221008,China;2.Key Laboratory of Ion Beam Bio-engineering,Chinese Academy of Sciences,Hefei 230031,China);Screening of Ge-enriched Cordyceps militaris strains by ion beam implantation[J];Science and Technology of Food Industry;2009-02
5 HUANG Xiao-dong1,CAI Jing-xiu2*,XU Li-xuan3,ZHENG Yue-bo2(1.Institute of Wetland,Quanzhou Normal College,Quanzhou 362000;2.College of Chemistry and Life Science,Quanzhou Normal University,Quanzhou 362000;3.Quanzhou Preschool Education College,Quanzhou 362000);GeO_2-enriched culture and antioxidant activity of total flavonoids of Inonotus obliquus[J];Food Science and Technology;2012-06
6 ZHAO Wei,WU Yinwei,YAO Wenhu,et al.Affiliated Second Hospital of Nanjing,Southeast University Medical College, Nanjing 210003, CHINA;Effect of organic-Ge-polyhexose and HAART on the coreceptor CCR_5 and CXCR_4 expression of peripheral blood T lymphocyte and the immunity in AIDS patients[J];Jiangsu Medical Journal;2008-03
【Secondary Citations】
Chinese Journal Full-text Database 4 Hits
1 WANG Guoyan;LIN Zhibin(Department of Pharmacology,Beijing Medical Univerxity 100083);ANTITUMOR AND IMMUNOPOTENTIATING EFFECT OF10-HYDROXY-2-DECENOIC ACID ONTUMOR-BEARING MICE[J];JOURNAL OF BEIJING MEDICAL UNIVERSITY;1996-05
2 Li Weiyi, Cheng Liping, Peng Wei, Zhu Yunfeng Gao Huibao Wang Yifei Department of Immunology, Shanghai Second Medical University;IMMUNOMODULATION OF ORGANIC GERMANIUM(GE-401) ON ANTIBODY PRODUCTION OF MOUSE B LYMPHOCYTE[J];;1991-04
3 ZHANG YAN;ZHANG He-Yun;LI Wei-Ping et al(Dept of phar Anhui Medical University,Hefei 230032);Effect of An Ji Fu on increase intelligence[J];CHINESE PHARMACOLOGICAL BULLETIN;1995-03
4 Gu Qin-long,et al.Ruijin Hospital of Shanghai Second Medical University,Shanghai 200025.;A study of antitumor effect and mecha-nism of tuftsin[J];CHINESE JOURNAL OF EXPERIMENTAL SURGERY;1994-06
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved