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《Carcinogenesis,Teratogenesis and Mutagenesis》 2005-06
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Influence of MianZeng-Ling on Mouse Erythrocyte Immunolo-gical Function and NK Cell Activity

WEI Jing-jian 1 ,LIU Cai-yu 1 ,WANG Yi-peng 2 , WANG Jing-ping 1 ,WANG Shun-xiang 1 (1.Henan Tumor Institute,Zhengzhou450008,Henan,China; 2.Jinshui District Hospital of Zhengzhou,Zhengzhou 450003,Henan,China)  
BACKGROUNDAIM: To study the influence of Mian-Zeng-Ling on mouse erythrocyte immunological function and Natural Killer(NK)cell activity. MATERIAL AND METHODS: The ratio of RBC-CR rosette,the ratio of RBC-IC rosette,the ratio of RBC-Ca rosette and NK cell activity were determined. RESULTS: Experiments showed mice erythrocytes could immunologically adhere to tumor cells.After peritoneal injection of cyclophosphamide,the ability of mice erythrocytes adhering to tumor cells was declined,Mian-Zeng-Ling could opposed this action,improving the adherent ability of erythrocytes.The effect of Mian-Zeng-Ling was superior to Zhen-Qi-Fu Zheng granlies sold in the market.Mian-Zeng-Ling also could oppose cyclophosphamide which reduced mouse NK cell activity,therefore improving and raising the activity of moccse NK cell. CONCLUSION: Mian-Zeng-Ling could improve erythrocyte immunological function and NK cell activity suppressed by cyclophosphamide.
【CateGory Index】: R285.5;
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