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《Carcinogenesis,Teratogenesis & Mutagenesis》 2006-01
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Studies on the Safety and Antimutagenicity of Lutein

WANG Ming-chen 1 ,ZHANG Shan-feng 1 ,MAO Hong-li 2 , JIN Guo-ping 1 ,DONG Zi-ming 1 (1.Department of Biochemistry and Molecular Biology,Medical College,Zhengzhou University,Zhengzhou 450052,China;2.The First Affiliated Hospital of Zhengzhou University,Zhengzhou450052,Henan,China.)  
BACKGROUNDAIM: To study the effects of lutein on mutagenicity and antimutation anti-mutagenicity. MATERIAL AND METHODS :The studies were conducted with Ames test. RESULTS: In Ames test,the mutagenicity of Lutein group was no more than2times that of the control group.In test,comparing with positive group,Lutein groups could decrease the colonies in TA 98 and TA 100 strains. CONCLUSION: No mutagenicity was observed with lutein in this study.Moreover,we demonstrated that lutein possessed significant antimutagenic properties.
【CateGory Index】: R285
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