Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Carcinogenesis,Teratogenesis & Mutagenesis》 2006-01
Add to Favorite Get Latest Update

Study on the Teratogenic Effects of Pseudoephedrine in Rats

SUN Xiao-ying 1 ,ZHANG Zhen-jun 1 ,BIAN Xue-feng 2 , CHEN Qing 1 ,YU Yan 1 (1.Department of Environmental Health,Xi'an Jiaotong University,Xi'an710061,China;2.Department of Health Statistics,Xi'an Jiaotong University,Xi'an710061,Shaanxi, China)  
BACKGROUNDAIM: This study was undertaken to determine the potential teratogenic effects of Pseudoephedrine on SD rats and to provide toxicological information. MATERIAL AND METHODS: SD pregnant rats were randomly divided into four groups:Pseudoephedrine50,100,200mg/kg and control.Conventional teratogenicity test was performed.Female rats was given Pseudoephedrine by gastric intubation at50,100,200mg/kg on days6-15of gestation. RESULTS: Adjusted weight gain of pregnant rats,body weight of fetuses and the number of dead fetuses were significantly different at200mg/kg when compared to controls. CONCLUSION: Among the range of experimental doses,pseudoephedrine was considered to have maternal toxicity,embryo toxicity and teratogenic effects in SD rats.
【CateGory Index】: R96
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 1 Hits
1 CHENG Pei-ying,QU Gui-juan,MA Hong-xia,DONG Xiao-qing(College of Animal Science and Technology,Jilin Agricultural University,Changchun 130118,China);Study of Mutagenic Effect of Glucoside Peptide Injection on Rats[J];Journal of Jilin Agricultural University;2007-03
Chinese Journal Full-text Database 1 Hits
1 Shi Yuxiang, Su Change (The PLA 251 Hospital, Zhangjiakou 075000, P. R. China);Application of Pseudoephedrine in Chinese and American OTC Drugs[J];China Pharmacist;2001-03
Chinese Journal Full-text Database 10 Hits
1 LIANG Hai-ying, ZHANG Xiao yuan, LIANG Song ping (Laboratory of Protein Chemistry, College of Life sciences, Hunan Normal University, Changsha 410081, China);THE STUDY ON MUTAGENICITY OF HUWEN ANALGESIC PEPTIDE[J];Carcinogenesis,Teratogenesis and Mutagenesis;2002-03
2 LIU Xiao_qiu, WANG Rong_xian, TIAN Qing_wei(Institute of Radiation Medicine Chinese Academy of Medical Sciences, Tianjin 300192 , China);MUTAGENICITY RESEARCH OF No.Ⅱ DRUG[J];Carcinogenesis,Teratogenesis and Mutagenesis;2003-01
3 MEI Shu-jiang,LIU Ya,WANG Bao- Gui,et al(1.Department of biiology,Shantou University Medical College,Shantou 51503 1,China;2.College o f Preventive Medicine,Jilin University,Changchun 130021, China;3.Health Supervision Office of Changchun Health Bureau Changchun 130021,China);STUDY ON ACUTE TOXICITY AND MUTAGENTICITY OF POLYOXOANIONS α-K_8H_2[SiW_9Ti_3O_40]·15H_2O[J];Carcinogenesis,Teratogenesis and Mutagenesis;2003-03
4 LIAO Xue1, WANG Jie1, SONG Hong-yu1, et al(1.National Research Center for New Drug Safety Evaluation ,Shenyang 110021,China;2.The Ninth Hospital of Shenyang, shenyang 110024,China);STUDY OF TER ATOGENICITY OF PIOGILISTAZONE HYDROCHLORIDA IN RATS[J];Carcinogenesis,Teratogenesis and Mutagenesis;2003-04
5 LIU Yong-xue,WANG Qiong,GAO Pei-yong (Department of Pharmacology and Toxicology,Beijing Institute of Radiation Medicine,Beijing100850,China);Examination of the Mutagenetic Effect of the Recombinant Staphylokinase[J];Carcinogenesis,Teratogenesis and Mutagenesis;2004-05
6 YU Yan 1 ,LIN Fei 2 ,ZHANG Rui-juan 1 ZHANG Zhen-jun 1 ,LI An-jing 1 (1.College of Medical Science,Xi'an Jiaotong University,Xi'an 710061,Shanxi China;2.Assessment Institute of Drugs and Biology Products of China,Beijing100050,China);The Toxicity Study of Recombinant Human Glucagon-like Peptide on Rats During the Period of Sensitive Teratogenesis[J];Carcinogenesis,Teratogenesis and Mutagenesis;2005-03
7 LIN Fei 1 ,LU Lian 1 ,YANG Xu-qing 2 ,CUI Wei-chuan 2 ,WANG Feng-min 2 (1.National Institute for the Control of Pharmaceutical and Biological Products,Beijing100050,China;2.The Science System Corporation of Beijing Xingda,Beijing100081,China);The Comparison Study of Major Target Organ Hurt Induced by Dicycloplatin and Its Derivates in Rats[J];Carcinogenesis,Teratogenesis and Mutagenesis;2005-05
8 PAN Jing-yuan,QIU Yin-sheng,YAN Han-chi,LING Sa (Center of Pharmacology and Toxicology,Hubei Pharmaceutical Industry Research Institute,Wuhan430061,Hubei,China);Study on the Teratogenicity of Erythromycin Propionate-N-Acetylcysteinate in Rats[J];Carcinogenesis,Teratogenesis & Mutagenesis;2006-01
9 WEI Xian-fei,TANG Rong-lan,GAN Yun-sheng,LUO Feng-jiao (Liuzhou Medical College, Liuzhou, Guangxi 545006, China);The Toxicity Attenuation and Antimutagenic Effect of Health-preserving Cigarettes Made From Chinese Herbal Medicine[J];Carcinogenesis,Teratogenesis & Mutagenesis;2007-01
10 LU Jing-tao1,XU De-xiang2,SUN Mei-fang2,WEI Ling-zhen2,SHEN Tong1,WEI Wei1(1.Institute of Clinical Pharmacology;2.Department of Toxicology,Anhui Medical University,Hefei 230032,China);Study on Teratogenicity of Glycosides of Chaenomeles Speciossa[J];Carcinogenesis,Teratogenesis & Mutagenesis;2008-01
China Proceedings of conference Full-text Database 4 Hits
1 LIU Xiaoqiu, HAN Ying, SHEN Xiu, ZHAO Ajin, ZHOU Zewei ( Institute of Radiation Medicine, Chinese Academy of Medical Sciences , Peking Union Medical College, Tianjin 300192, China);Mutagenicity Research of NiKeAn[A];[C];2010
2 LIU Chun,ZHAO Yu-mei (Hainan Provincial Institute for Drug Control,Haikou 570216,China);Safety study on local application of Fukunqing pill[A];[C];2009
3 XU Di~1,CHEN Xiu-na~2,YE Ming-xia~1,XIONG Mei-yun~1,ZHOU Shun-chang~1,KONG Li-jia~1 1 Faculty of Laboratory Animal Science,Tongji Medical College.Huazhong University of Science and Technology,Wuhan,430030,China;2.Research Center of Pesticide Toxicology,Tongji Medical College.Huazhong University of Science and Technology,Wuhan,430030,China;);Study On the quality control of chronic toxicity and carcinogenicity test on rats[A];[C];2010
4 JIA Dan-bing,LI Shan,LI nai-min,TANG Li-ming,LI Chun-jie,Gong Yuan-xin (People's Liberation Army No.211 Hospital,Harbin,150080,China);Long-term toxicity study on Shenjiang Suoyang Yiqi Tables in male SD rats[A];[C];2012
Chinese Journal Full-text Database 10 Hits
1 ZHOU Yi-ping,CHEN Qi-you,CHEN Si-yan,YANG Jing-hua (Hubei Pharmaceutical Industry Research Institute, Wuhan430061,China);Teratogenicity of Arbidol Hydrochloride in Rats[J];Carcinogenesis,Teratogenesis & Mutagenesis;2006-01
2 PAN Jing-yuan,QIU Yin-sheng,YAN Han-chi,LING Sa (Center of Pharmacology and Toxicology,Hubei Pharmaceutical Industry Research Institute,Wuhan430061,Hubei,China);Study on the Teratogenicity of Erythromycin Propionate-N-Acetylcysteinate in Rats[J];Carcinogenesis,Teratogenesis & Mutagenesis;2006-01
3 Lu Yifang, Wang Qiujing, Yang Shijie (Department of Pharmacology);Effect of mentha oil on termination of preegnancy in mice[J];;1989-05
4 LIU Sheng 2, CHEN Wan Sheng 1, QIAO Chuan Zhuo 1, ZHENG Shui Qing 1, ZENG Ming 1,ZHANG Han Ming 1, SONG Zhao Jun 1 (1. Department of Pharmacognosy, College of Pharmacy, Second Military Medical University, Shanghai 200433, China; 2. Department;Antiviral action of Radix Isatidis and Folium Isatidis from different germplasm against influenza A virus[J];ACADEMIC JOURNAL OF SECOND MILITARY MEDICAL UNIVERSITY;2000-03
5 Chen Qun,Wang Shengchun (Department of Microbiology,Guangdong Medical College,Zhanjiang 524023);Experimental study of eliminating action of Baicalin and Rhizoma Coptidis on R plasmid of E.coli[J];JOURNAL OF GUANGDONG MEDICAL COLLEGE;1998-Z1
6 ZHANG Xiao-Lin, LI Jia-Tai(Institute of Clinical Pharmacology, The First Teaching Hospital, Beijing Medical University, Beijing, 100083);THE DISTRIBUTION AND EXPRESSION OF ACTIVE EFFLUX PUMP acrAB IN CLINICAL ISOLATES OF ESCHERICHIA COLI[J];THE CHINESE JOURNAL OF CLINICAL PHARMACOLOGY;1999-03
7 ZHOU Yu-jie,LU Shan,WANG Zhi-ying(Nanjing University Traditional Chinese Medicine,Jiangsu,Nanjing 210029,China);Effect of Puerarin in Inflammatory,Oxidative Stress,Remodeling of Airway on Chronic Obstructive Pulmonary Disease in Rats[J];Journal of Clinical Research;2007-08
8 DUAN Li-ping(the hospital of inner mongolia medicine and Chinese medicine in baotou,baotou 014010,china);Analysis Of Efficacy Of Medicine In Licorice Root[J];Journal of Diseases Monitor & Control;2009-02
9 LEI Lian-cheng, HAN Wen-yu, QIAO Hong-wei ( Faculty of Animal Science and Technology, Quartermaster University of PLA , Changchun , Jilin 130062, China ; College of Animal Science and Technology, Xinjiang Agricultural University, Urumqi, Xinjiang 843300, China);Preparation of Drug Resistance Inhibitors of Escherichia coli[J];Journal of Jilin Agricultural University;2003-04
10 SONG Zhan-yun1,FENG Xin1,HAN Wen-yu1,DING Zhuang1,CHEN Ao-di2, LEI Lian-cheng1(1.College of Animal Science and Veterinary Medicine,Jilin University,Changchun 130062,China;2.Editorial Board on Chinese Journal of Veterinary Science,Changchun 130062,China);Selection of Chinese Herbal Medicine Staphylococcus aureus norA Efflux Pump Inhibitor[J];Journal of Jilin Agricultural University;2007-03
【Secondary References】
Chinese Journal Full-text Database 4 Hits
1 NI Jia-ning,L Ying-jun,BAO En-dong(College of Veterinary Medicine,Nanjing Agricultural University,Nanjing 210095,China);Common toxicity and mutagenic action of poly I∶C in mice[J];Journal of Nanjing Agricultural University;2008-04
2 HE Li-li 1,YANG Li-kai 2,DENG Li 2,GONG Tao 2,SUN Xun 2,ZHANG Zhi-rong 2(1.School of Chemistry and Environment Protection Engineering,Southwest University for Nationalities,Chengdu 610041,P.R.C.;2.Key Laboratory of Drug Targeting and Novel Drug Delivery Systems,West China School of Pharmacy,Sichuan University,Chengdu 610041,P.R.C.);Preparing metabolic activation system and measuring protein contents[J];Journal of Southwest University for Nationalities(Natural Science Edition);2010-02
3 DONG Xiao-qing,QU Gui-juan,CHENG Pei-ying(College of Animal Science and Technology,Jilin Agricultural University,Changchun 130118;China);The Effect of Immune Organs and Blood Indices of Glucoside Peptide Injection for Pig[J];Chinese Journal of Veterinary Drug;2010-01
4 DONG Xiao-qing,QU Gui-juan,MA Hong-xia(College of Animal Science and Technology,Jilin Agricultural University,Changchun 130118,China);Effect of teratogenesis of glucoside peptide injection for pregnant mice[J];Chinese Journal of Veterinary Medicine;2012-04
【Secondary Citations】
Chinese Journal Full-text Database 4 Hits
1 Chen Jiaying,Qian Hongmei,Sun Fenzhi,Wu Songyun (Jiangsu Institute of Meteria Media,Nanjing,210009);Anti-nasal Decongestant Effect of Kalefei in Rabbits[J];JOURNAL OF NANJING RAILWAY MEDICAL COLLEGE;1998-01
2 Zhao Qiuxian, Yuan Bingxiang, Zhao Zhenghang, et al(Department of Pharmaceutics, First Affiliated Hospital);THE RELIEVING OF COUGH BY COMPOUND PSEUDOEPHEDRINE AND ITS ACUTE TOXICITY[J];Journal of Xi'an Medical University(Chinese);1997-01
3 XIN Jian_Bao, ZHOU Xiao_Qin, XIONG Xian_Zhi, LI Yuan_Gui(Department of Respiratry Disease, Xiehe Hospital, Tongji Medical University, Wuhan HUBEI 430022) LIU Jin, ZHANG Zhen_Xiang(Department of Respiratory Disease, Tongji Hospital, Tongji Medica;Clinical testification of compound dextromethorphan granule vs Meiyuweima Jiaonang[J];CHINESE JOURNAL OF NEW DRUGS AND CLINICAL REMEDIES;1999-01
4 CAO Fang LIU Shu-Qing FENG Wei-YiKANG Ai-Qun YANG Bing-Xing(Department of Pharmacology, Xian Medical University 710061);Effect of pseudoephedrine hydrochloride mixture onthe histamine-induced contraction of isolated bronchialsmooth muscle in guinea pig & the prescription analysis for the mixture[J];Chinese Journal of Clinical Pharmacology and Therapeutics;1999-02
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved