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《Carcinogenesis,Teratogenesis & Mutagenesis》 2006-03
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The Expression of Vascular Endothelial Growth Factor in Breast Cancer Cell Lines

KANG Zhen-qiao1, JI Yan-xia2 , YANG Zhi-yong1,SU Guang1,CUI Yan-zhi3 (1. Handan the Second Hospital,056001, Hebei, China; 2. Handan Central Hospital, Handan 056001, Hebei, China;3. Shijiazhuang the First Hospital, Shijiazhuang 050011, Hebei, China)  
BACKGROUND AIM: To study the expression of VEGF in human breast cancer cells (MCF-7、MDA-MB-231). MATERIAL AND METHODS: The protein expression of VEGF in human breast cancer cell lines was studied by immunohistochemistry staining. Expression of VEGF mRNA in human breast cancer cell lines was determined by reverse transcriptase-polymerase chain reaction (RT-PCR) method. RESULTS: The high expression of VEGF mRNA in breast cell lines was confirmed by RT-PCR analysis and imunohistochemistry.VEGF165 and VEGF121 were identified as the predominant species produced in breast cancer cell lines (MCF-7、MDA-MB-231). The expression level of VEGF165 in MDA-MB-231 cells was higher than that in MCF-7 cells. CONCLUSION: Breast cancer cell lines(MCF-7、MDA-MB-231) showed higher expression of VEGF, and the level of VEGF165 expression conclated to do with the biological characteristics of the breast cancer cells.
【CateGory Index】: R737.9
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Chinese Journal Full-text Database 6 Hits
1 WANG Xiao-bing, YANG Qing-xu, PEI Xiao-juan Department of Pathology, Huizhou Central Hospital, Huizhou 516001, China;Expression of angiogenesis-related factors in invasive breast cancer and its clinical significance[J];Journal of Southern Medical University;2006-06
2 Zeng Jian, Lu Yunfei,Lin Jinling,et al(Department of Surgery, the First Affiliated Hospital of Guangxi Medical University, Nanning 530021,China);THE RELATIONSHIP BETWEEN VASCULAR ENDOTHELIAL GROWTH FACTOR,LYMPH NODE METASTASIS AND PROGNOSIS OF BREAST CARCINOMA[J];Journal of Guangxi Medical University;2001-05
3 HUANG Xuan-dong, ZHOU Xue-rui, SHEN Yang, PING Hong.Department of Surgical Oncology,Huai'an Hospital,Affiliated to Huai'an Medical College,Huai'an 223002,China;Expression of vascular endothelial growth factor in mammary carcinoma and its relationship with cancer biological characteristics[J];Chinese Clinical Oncology;2005-06
4 Xu Li,Li Yan,Zhou Xiong,et al;Detection and clinical significance of vascular endophelial growth factor in the sera of breast cancer patients[J];Shandong Medical Journal;2002-02
5 WANG Ren-qi,KONG Fan-ming.Department of General Surgery,People's Hospital of Puyang City,Puyang,457000;Expression of BAG-1 and VEGF and its Significance in Breast Carcinoma[J];The Practical Journal of Cancer;2005-04
6 ZONG Jian-chun,WU Cheng-yi,WU Kai-nan.Department of General Surgery,The First Affiliated Hospital,Chongqing University of Medical Science,Chongqing 400016,China;Effect of arsenic trioxide on the VEGF expression in human breast carcinoma cells line[J];Chinese Journal of Experimental Surgery;2005-05
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