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《Carcinogenesis,Teratogenesis & Mutagenesis》 2007-01
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Study About Anti-tumor Effect of Pulsatilla Chinensis(Bunge)Regel Extracts in Vitro

ZHU Jing-tong,BAI Yu ,SI Wen-xiu ,LIU Hong-xi,REN Qu-hui (NCPC Drug R&D Co,Ltd,Shijiazhuang 050015,China)  
BACKGROUND AIM: To study the anti-tumor effect of [pulsatilla chinensis(Bunge)regel,PCR] extracts. MATERAIALS AND METHODS: The effect of PCR extracts on the proliferation of tumor cell lines were assayed in vitro using 3-[4,5-di methylthiazol-2-yl]-2,5 diphenyltetrazoliumbromide colorimetry method.The anti-tumor active component of PCR extracts was separated and purified using three steps methods. RESULTS: PCR extracts markedly inhibited the proliferation of tumor cell lines and in a dose-dependent manner. The anti-tumor active component was indentified. CONCLUSION: PCR awaits further development as an anti-tumor drug.
【CateGory Index】: R285
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【References】
Chinese Journal Full-text Database 8 Hits
1 SHI Xin-qiang,SHEN Ye-shou,WEI Zi,MA Jin-bao(Institute of Biochmistry and Microbiology,School of Life Science,Anhui Universitya;The Key Lab of Chinese Traditional Medicine Research and Development of Anhui Province,Hefei 230039,China);Inhibitory Effects of Phellinus Linteus Intracellular Polysaccharide on the Proliferation of Leukemic Cells K562[J];Carcinogenesis,Teratogenesis & Mutagenesis;2007-06
2 RUI Meng1, LIU Chang-ting2,DUAN Yun-you1,YU Xiao-dan3, HOU Chun-mei3.(1. VIP ward 1,Naval General Hospital, Beijing 100037;2.Respiratory Department of Nanlou,General Hospital of PLA,Beijing 100853;3.Institute of Basic Medical Sciences,Academy of Military Medical Science, Beijing 100850,China);Growth-inhibiting Effects of Paclitaxel on p53-deficient Strain of Human Lung Cancer H1299 Cells[J];Carcinogenesis,Teratogenesis & Mutagenesis;2008-03
3 WANG Yao (Key Laboratory of Forest Tree Genetic Improvement and Biotechnology,Ministry of Education,College of Life Sciences of Northeast Forestry University, Harbin,Heilongjiang 150040);Advance of Research on the Exploitation and Utilization of Poisonous Plants Resources in Heilongjiang Province[J];Journal of Anhui Agricultural Sciences;2009-09
4 WANG Gui-qin1,ABDUSALERK N2,SHI Wei-jing1(1.Biological Department of Anhui Science and Technology College,Fengyang 233100,Anhui,China;2.Resource and Environment College,Xinjiang University,Urumqi 830046,Xinjiang,China);Anatomical Structure Comparison and Barbloin Histochemical Localization of Different Growing Ages Pulsatilla chinensis[J];Acta Laser Biology Sinica;2008-03
5 HUA Yun-Fen1,WU Jiang-Lin2,QIAN Jun-Qing1(1.College of Pharmaceutical Sciences,Zhejiang University of Technology,Hangzhou 310014,China;2.Center of Inspection and Testing for Quality of Agriculture Products,Zhejiang Province,Hangzhou 310020,China);Inhibitory effect of fatty acids from specifically-cultivated Chrysomya megacephala (Fabricius) (Diptera:Calliphoridae) larvae on tumor cells and HIV-1 integrase in vitro and their ingredient analysis[J];Acta Entomologica Sinica;2008-02
6 JIANG Fengyu,SUN Shu,LI Xifeng,SUN Dongzhi Medical College of Yanbian University,Yanji 133002,China;Mechanism of Isomycin Derivant Induced Apoptosis of Human Breast Carcinoma Cell Line[J];Tianjin Medical Journal;2012-09
7 JIANG Feng-yu,CHEN Ding-fa,SUN Shu.(Department of Pathology,Medical College of Yanbian University,Yanji 133000,China);Experiment Research and Clinical Application of Pulsatilla[J];Medical Recapitulate;2009-24
8 LIU Lei-lei2,CHEN Juan1,SHI Yan-ping1,2 1.Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province,Lanzhou Institute of Chemical Physics,Chinese Academy of Sciences,Lanzhou 730000,China 2.State Key Laboratory of Applied Organic Chemistry,Lanzhou University,Lanzhou 730000,China;Advances in studies on antitumor of Chinese materia medica with heat-clearing and toxin-resolving functions[J];Chinese Traditional and Herbal Drugs;2012-06
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 JIANG Dong xia\+1, YANG Sheng li\+2, HE Lin\+1 (1. Department of Molecular Biology, Henan Tumour Institute, Zhengzhou\ 450003, China; 2. Department of Esophageal Cancer Research, Zhengzhou University, Zhengzhou 450052, China);STUDY ON THE INHERENT AND THE ACQUIRED EXPRESSION OF mdr-1 IN DRUG RESISTANCE IN THE PERIPHERAL LYMPHOCYTE OF PATIENTS WITH MALIGNANT TUMOUR[J];Carcinogenesis,Teratogenesis and Mutagenesis;2002-04
2 HE Lin\+1, ZHANG Qiao\+2, HU Jie ying\+1 (1. Department of Molecular Biology, Henan Tumour Institute, Zhengzhou\ 450003, China; 2. School of Public Health, Zhengzhou University, Zhengzhou 450052, China);STUDY ON THE RELATIVITY OF mdr-1 EXPRESSION INDUCED BY DRUG BETWEEN FRESH TUMOUR CELLS AND THE PERIPHERAL LYMPHOCYTES IN VITRO[J];Carcinogenesis,Teratogenesis and Mutagenesis;2002-04
3 HE Xiao-qiong, CHEN Yan-hong, XIONG Xiang-ling (Nutrition and Food Science Institute, Kunming Medical College, Kunming 650031, China);Inhibitory Effect of AMH Extracted from Fungi Plant Tricholoma Matsutake on the Mutagenicity of Cigarette Smoke Condensate in vitro[J];Carcinogenesis,Teratogenesis and Mutagenesis;2004-01
4 HE Zhi-ying 1 ,JIANG Qian-li 2 ,YAO Yu-cheng 1 ,et al (1.Department of Cell Biology,Second Medical University,Shanghai200433,China;2.Department of hematology,Changhai Hospital,Shanghai200433,China);Expression and Cytotoxicity of RFP-labeled Yeast Cytosine Deaminase in HeLa Cells[J];Carcinogenesis,Teratogenesis and Mutagenesis;2004-05
5 SHAN Bao-en 1 ,LIANG Wen-jie 1 ,REN Feng-zhi 2 ,et al (Research Center,The Fourth Hospital of Hebei Medical University,Shijiazhuang050011,China;2.NCPC New Drug R&D co.Ltd,Shijiazhuang050015,China);Study about Anti-tumor Effect of Rhizoma Menispermi Extracts in Vitro[J];Carcinogenesis,Teratogenesis and Mutagenesis;2004-05
6 SHAN Bao-en,LI Jun-xin,ZHANG Jing,LIANG Wen-jie,LI Hong-fen(Science and Research Center,The Fourth Hospital of Hebei Medical University,Hebei Shijiazhuang050011,China);The Anti-tumor in Vitro Effect of Cortex Periplocae and Its Analogues Extracted[J];Carcinogenesis,Teratogenesis and Mutagenesis;2005-05
7 SHAN Bao-en1, REN Feng-zhi2, LIANG Wen-jie1,3,ZHANG Jing1,Li Qiao-xia1, ZENG Ya-ping4(1.Research Center, the Fourth Hospital of Hebei Medical University, Shijiazhuang, 050011,China;2.North China Pharmacal Coperation China;3.Hebei Medical University Shijiazhuang 050011,China;4.Hebei Science and Technology Publishing House,Shijiazhuang,050073, China );Isolation and Purification of Antitumor Component in Rhizoma Menispermi and Analysis of Its Activity[J];Carcinogenesis,Teratogenesis & Mutagenesis;2006-03
8 ZHENG Li-jun,SHEN Ye-shou ,JI Jun-qiu,LI Yi-ming(Laboratory of Glycoconjugate and Glycotechnology,School of Life Science,Anhui University,Hefei,Anhui,230039,China);The Antimutation and Antioxidation Effects of Phellinus Igniarius Intracellular Polysaccharide[J];Carcinogenesis,Teratogenesis & Mutagenesis;2006-06
9 ZHANG Geng-yue,ZHOU Xiao-jun, SONG Lian-sheng(Jilin Provincal Tumor Research Institute, Changchun 130012,China);Mutagenicity Study on Liranaftate[J];Carcinogenesis,Teratogenesis & Mutagenesis;2007-02
10 SHAN Bao-en1, LI Jun-xin2, JING Xiang-yu2, ZHANG Chao1(1.Science and Research Center, The Fourth Hospital of Hebei Medical University, Shijiazhuang 050011,Hebei;2. Women and Children's Medical Center,Qingdao 266000,Shandong,China);The Anti-tumor Effect of Cortex Periplocae Extract in Vitro and in Vivo[J];Carcinogenesis,Teratogenesis & Mutagenesis;2007-04
China Proceedings of conference Full-text Database 9 Hits
1 (School of Life Science and Biopharmaceutics,Shenyang Pharmaceutical University,Shenyang 110016,China) HAO Dong-hai,CAO Ke,LIU Jian,ZHANG Yu-yang;Application of cell injury models in screening for anti-ischemia activity of compounds[A];[C];2011
2 Wang Wei Wang Dawen Zuo Hongyan Yao Hua Chang Gongmin Wang Ruijuan Gao Yabing Wang Shuiming Dong Bo Zhang Zhiyi Pang Ruiyun (1.Institute of Radiation Medicine,Academy of Military Medical Science,NO.27,Tai Ping Road,Beijing 100850,China;2.Department of Pathology,the 401~(st) hospital of PLA.QingDao 266071,China);The injury effects induced by different bands of electromagnetic radiation on lymphocyte[A];[C];2008
3 Xu Fangming Guoyi~1 Chen Shuangbai~1 (Biomedical engineering department of Chongqi university if medical science,Chongqi,400016; Tianjin college of traditional Chinise medicine,Tianjin,300193);Effects of dadun with acupuncture on metabolizability of energy in Acute Hypoxia Mice[A];[C];2005
4 ;Experimental Study on anti-anxiety effects and mechanism in mmice of Shu Dihuang[A];[C];2006
5 Lai Xiao-ping, Chen Jian-nan, Ye Mu-rong, Hou Shao-zhen, Li Geng- (Guangzhou University of Traditional Chinese Medicine, Guangzhou, 510405 );The therapeutic Effect of Isodon lophanthoides var.gerardianus (Benth.) H.Hara on liver-injured animal models[A];[C];2006
6 WANG-Gang~1 LIU-Bin~1 QI-Bin~2 CHEN-Huaqiong~1 DU Biao~3 (1.Children's Hospital,Chongqing University of Medical Sciences,Chongqing 400014,China, 2.Shiyan Maternal and Child health Hospital,Shiyan 442001; 3 Dept.of pharmacy,Hospital Chong qing sanxia chong qing 404000);Experiment study on antihepatic fibrosis effect of chai-hu and ge-gen in wistar mice[A];[C];2007
7 LI Ying MA Yong-jiang XU Li-na ZHANG Yuan LI Yu-gu (College of Veterinary Medicine,South China Agriculture University,Guang zhou,Guangdong,510642,China);The Effects of different culture systems on proliferation activities of mouse thymic epithelial cells[A];[C];2008
8 WANG Jin-guo,TU Jian,ZHAO De-ming~* (China agricultural university,National animal TSE laboratory,Beijing 100193,China);The effect of acidation for removing Pseudorabies Virus[A];[C];2010
9 Hua Haiying Fan Yuhui (Henan Institute of Medical Sciences,Zhengzhou 450052);Effects of Tetramethylpyrazine on Expression of α-SMA Muscle Actin and Nuclear Factor-κB in Human Hepatic Stellate Cells[A];[C];2007
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 ZHU Wei-yun, PANG Zhu-lin, LIANG Min-yi, et al(Department of Medical Genetics and Cell Biology, Guangzhou Medical College, Guangzhou 510182,China);THE EFFECT OF TARAXACUM MONGO TO INHIBIT THE MUTATION IN THE BONE MARROW LYMPHOCYTE OF MICE INDUCED BY CYCLOPHOSPHAMIDE[J];Carcinogenesis,Teratogenesis and Mutagenesis;2003-03
2 SHAN Bao-en 1 ,LIANG Wen-jie 1 ,REN Feng-zhi 2 ,et al (Research Center,The Fourth Hospital of Hebei Medical University,Shijiazhuang050011,China;2.NCPC New Drug R&D co.Ltd,Shijiazhuang050015,China);Study about Anti-tumor Effect of Rhizoma Menispermi Extracts in Vitro[J];Carcinogenesis,Teratogenesis and Mutagenesis;2004-05
3 ZHANG Jing 1 ,SHAN Bao-en 1, ,LIU Gang-san 2 , ZHAO Xue-tao 1 ,CHEN Shu-hong 2 (1.Research Center,the Fourth Hospital of Hebei Medical University,Shijiazhuang050011,Hebei,China;2.New Drug Research and Development Co.,Ltd.of North China Pharmaceutical Corporation,Shijiazhuang050015,Hebei,China);Anti-tumor Activity of Extract from Periploca Sepium Bge[J];Carcinogenesis,Teratogenesis & Mutagenesis;2006-02
4 SHAN Bao-en1, REN Feng-zhi2, LIANG Wen-jie1,3,ZHANG Jing1,Li Qiao-xia1, ZENG Ya-ping4(1.Research Center, the Fourth Hospital of Hebei Medical University, Shijiazhuang, 050011,China;2.North China Pharmacal Coperation China;3.Hebei Medical University Shijiazhuang 050011,China;4.Hebei Science and Technology Publishing House,Shijiazhuang,050073, China );Isolation and Purification of Antitumor Component in Rhizoma Menispermi and Analysis of Its Activity[J];Carcinogenesis,Teratogenesis & Mutagenesis;2006-03
5 YIN Feng-ling1, LU Jing1, LI Ai-ping2, GU Deng-an2, HAN Su-ping1,*, ZHOU Jian-wei2(1. Department of Gynecology, Jiangsu Provincial Hospital, Nanjing 210029,Jiangsu,China; 2. Department of Molecular Cell Biology and Toxicology,School of Public Health, Nanjing Medical University, Nanjing , 210029,Jiangsu,China);Combined Effects of 4-HPR and DDP on the Proliferation and Apoptosis of HeLa Cells[J];Carcinogenesis,Teratogenesis & Mutagenesis;2006-03
6 ZHENG Li-jun,SHEN Ye-shou ,JI Jun-qiu,LI Yi-ming(Laboratory of Glycoconjugate and Glycotechnology,School of Life Science,Anhui University,Hefei,Anhui,230039,China);The Antimutation and Antioxidation Effects of Phellinus Igniarius Intracellular Polysaccharide[J];Carcinogenesis,Teratogenesis & Mutagenesis;2006-06
7 ZHANG Nan1, ZI Xiao-yuan1, XIONG Jun1, YAO Yu-cheng1,LI Wen-lin1, BA Yue2, ZHU Hai-ying1, LI Jian-xiu1, WANG Xin-min1, HU Yi-ping1, (1. Department of Cell Biology, Second Military Medical University,Shanghai 200433, China; 2. Department of Environmental Health, College of Public Health, Zhengzhou University, Zhengzhou 450052, Henan, China);Apoptosis Induced by Hepatitis B Virus X Protein in HeLa Cells and Transgenic Mice Hepatocytes[J];Carcinogenesis,Teratogenesis & Mutagenesis;2007-02
8 WANG Xiao-hua,WANG Chao-qun(Anhui Academy of Medical and Science,Hefei 230061,China);Rearch on Quantitative Determination of Total Flavonoids from Herba Euphorbiae Humifusae[J];Anhui Chemical Industry;2010-02
9 JIANG Jin-qing et al (College of Animal Science,Henan Institute of Science and Technology,Xinxiang,Henan 453003);Study on Enhancing the Cell Immunity of Broiler with Chinese Herbal Medicine[J];Journal of Anhui Agricultural Sciences;2006-18
10 LI Hong-fang et al (State Key Laboratory of Phytochemistry and Plant Resources in West China,Kunming Institute of Botany of Chinese Academy of Sciences,Kunming,Yunnan 650204);Research Progress on the Chemical Components and Pharmacological Action of Polygonum perfoliatum L.[J];Journal of Anhui Agricultural Sciences;2008-27
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 RUI Meng~1,CONG Mei~1,DUAN Yun-you~1,HOU Chun-mei~2 (1.Respiratory Department of Cadre Wards,Naval General Hospital, Beijing 10004;2.Institute of Basic Medical Science,Academy of Military Science,Beijing 100850,China);Study of paclitaxel effects on human lung cancer cell lines with different p53 genotype[J];Carcinogenesis,Teratogenesis & Mutagenesis;2012-01
2 CHENG Hai-tao1,LIU De-jiang1,LUO Zhi-wen1,LIU Juan2(1.Life Science College of Jiamusi University,Jiamusi,Heilongjiang 154007;2.Pharmacy College of Jiamusi University,Jiamusi,Heilongjiang 154007);Resources Investigation of Wild Toxic Plants in Daliangzihe National Forest Park[J];Heilongjiang Agricultural Sciences;2012-04
3 HOU Wei-zhuo,ZHEN Zhan-xuan*,LI Yun-xiang,YANG Gui-ming,LI Ji-sheng,LI Na Sericultural Institute of Chengde Medical College,Chengde 067000,China;Toxicity Effects of Water Extract of Euphorbia fischeriana Steud.against Silkworm(Bombyx mori)[J];植物病虫害研究(英文版);2011-01
4 SUN Xiao-ya,LIU Hong-xia,ZHANG Guo-gang(School of Traditional Chinese Materia Medica,Shenyang Pharmaceutical University,Shenyang 110016,China);Progress on Chrysomyia megacephala Larvae breeded by toad and Chrysomyia megacephala Larvae[J];Journal of Shenyang Pharmaceutical University;2011-07
5 SUN Xiao-ya,LIU Hong-xia,YUE Liang,SHEN Wen-juan,ZHANG Guo-gang(School of Traditional Chinese Materia Medica,Shenyang Pharmaceutical University,Shenyang 110016,China);Quantitative determination of cinobufagin in maggot bred by toad[J];Journal of Shenyang Pharmaceutical University;2012-05
6 LI Hui-min,YIN Chang-chang,WU Jia-zhong,ZHANG Lei(Basic Medical College,Jiujiang College,Jiangxi Jiujiang 332000,China);Inhibitory Effect of Different Extract Parts from Arachniodes exilis on HIV-1 IN Activities[J];Lishizhen Medicine and Materia Medica Research;2010-11
7 LI Hui-min, YIN Chang-chang, WU Jia-zhong, ZHANG Lei (Medical School,Jiujiang College,Jiangxi,Jiujiang 332000,China);Anti-HIV-1 RT Effect of Different Extracts from Arachniodes exilis Ching[J];Lishizhen Medicine and Materia Medica Research;2011-09
8 LI Cong,QIU Li-li,ZHANG Yong-qing(Shandong University of Traditional Chinese Medicine,Jinan 250355,Shandong,China);Advances in Study on Pharmacological Effects of Fungi in the Genus Phellinus[J];Chinese Archives of Traditional Chinese Medicine;2009-07
9 TANG Boya1,YANG Yifang1*,HUANG Chunyue1,LUO Zeyuan2,LI Cunyong2(1.State Key Lab.of New Drug and Pharmaceutical Process,Shanghai Institute of Pharmaceutical Industry,China State Institute of Pharmaceutical Industry,Shanghai 200040;2.Dihon Pharmaceutical Group Co.,Ltd.,Kunming 650106);HPLC Fingerprint Spectra for Discrimination of Spurious Breed of Radix Pulsatillae[J];Chinese Journal of Pharmaceuticals;2013-03
10 YANG Yan-jing,YAN Xiao-jing,ZHANG Li*,DING An-wei(Key Laboratory for High Technology Research of Traditional Chinese Medicine Formulae of Jiangsu Province, Nanjing University of Chinese Medicine,Nanjing 210046,China);Study on reducing mechanism of hepatotoxicity induced by ethyl acetate fractions of Kansui Radix stir-baked with vinegar in mice[J];China Journal of Chinese Materia Medica;2013-12
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