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《Carcinogenesis,Teratogenesis & Mutagenesis》 2008-04
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Protective Effects of Huangqi on Vascular Endothelial Cells Exposed to High Gluose

FAN Ke1,CHEN Pei-hong2,WU Qing3(1.Liyuan Hospital,Tongji Medical College of Huazhong University of Science and Technology,Wuhan 430000;2.Wuhan Hospital of Tradional Chinese Medicine,Wuhan 430014;3.Institute of Hematotogy Union Hospital,Tongji Medical Colllege of Huazhong University of Science and Technology,Wuhan 430022,China)  
BACKGROUND AND AIM: To evaluate the protective effects of Huangqi on the damage of high glucose on vascular endothelial cell(VEC-304)in vitro.MATERIALS AND METHODS: The model of human umbilical vein endothelial cells(VEC-304) damage was induced by 50% glucose for 4 h.The cells were pretreated with three concentrations of Huangqi solution for 24 h,before they were exposed to glucose.MTT and protein levels in cells were determined after 4 h.The expression of VEGF was investigated by RT-PCR and immunohistochemistry methods.RESULTS: MTT and protein levels in cells of the normal control group amd Huangqi-treated groups were higher than in glucose-damaged group without huangqi(P0.05).The expression of VEGF was inhibited by glucose.CONCLUSION: Huangqi could protect the damages of VEC-304 endothelial cells induced by high glucose.
【CateGory Index】: R285
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【Citations】
Chinese Journal Full-text Database 1 Hits
1 YANG Fu-guo,DONG Guo-xiong,ZHANG She-hua.Department of Cardiology,the Affiliated Hospital of Medical College ofQingdao University.Qingdao266003,China;Protective Effects of Astragalus Membranaceus Injection on the Endothelial Cells Injured by Hypoxia-Reoxygenation[J];Journal of Chinese Microcirculation;2004-03
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 DING Yin run, WANG Xiao yan, WANG Xu (Genetic laboratory, School of Life Sciences, Yunnan Normal University, Kunming 650092, China);ANEUPLOIDY INDUCTION BY THE WATER EXTRACT OF TRIPTERYGIUM HYPOGLAUCUM(LE-VEL) HUTCH IN MOUSE BONE MARROW CELLS DETECTED BY FISH[J];Carcinogenesis,Teratogenesis and Mutagenesis;2002-03
2 ZHOU Yi-feng et al (Institute of Botany,Jiangsu Province and Chinese Academy of Sciences,Nanjing,Jiangsu 210014);Distribution and Dynamic Variation of Paeonol in Cynanchun paniculatum[J];Journal of Anhui Agricultural Sciences;2006-22
3 LUO Xian-hua et al (Tongren Vocational Technology College, Tongren, Guizhou 554300);Comparison of Extraction Techniques of Total Flavonoids in Chrysanthemum Indicun[J];Journal of Anhui Agricultural Sciences;2007-26
4 ZHANG Wan-feng (Department of Chemistry of Ankang College,Ankang, Shaanxi 725000);Study on Chlorogenic Acid in Leaves of Eucommia ulmoides Olive in Different Month[J];Journal of Anhui Agricultural Sciences;2008-19
5 HUANG Zhao Gang,LI Shao Ping,ZHANG Ping,XIA Quan,ZHANG Yong Hua 1 (Dept of Pharmacy,The First Affiliated Hospital of Anhui Medical University,Hefei 230022; 1Sino America Huadong Pharmacy Co. Ltd,Hangzhou 210029);Study on liver-protection of mycelia of artifical fermentation cordyceps and its extraction[J];Anhui Medical and Pharmaceutical Journal;2003-02
6 Li Zhongnan,Chen Huaizhen,Han Mingxiang,Yang Liwen,Hu Shunjin (The First Affiliated Hospital of Anhui TCM College,Hefei 230031,China);30 CASES OF CHRONIC URETHRITIS TREATED BY NIAOLUQING[J];JOURNAL OF ANHUI TRADITIONAL CHINESE MEDICAL COLLEGE;2000-02
7 YANG Yu fu, L Xiong wen, MA Chuan geng (Dept. of pharmacy, Anhui Medical University, Anhui Hefei 230032, China);EFFECT OF HUOLIJING GRANULES ON ABILITIES OF LEARNING AND MEMORY IN NORMAL ADULT RATS[J];Journal of Anhui Traditional Chinese Medical College;2002-05
8 CHEN Hua dong, ZHANG Yu liang,WU Jun,XUE Song (The 421th Hospital, PLA, Guangdong Guangzhou 510310, China);Clinical Observation on the Treatment of Fatty Liver with Liver-soothing and Lipid-reducing Decoction[J];Journal of Anhui Traditional Chinese Medical College;2003-06
9 JIANG Feng rong, DAI Xiao ming, HUANG Yu fang, TANG De cai, CHEN Xue qing (The Basic Department of Nanjing University of Traditional Chinese Medicine, Jiangsu Nanjing 210029, China);Effect of Cough-easing Granule on Histological Morphology of the lungs and Bronchus in Mice with Chronic Bronchitis[J];Journal of Anhui Traditional Chinese Medical College;2004-02
10 SUN Jia-zhong,LIANG Jiu-ying,LI Jing,WANG Tao(The Hospital of Anhui Corps of People's Armed Police Affiliated to Anhui College of Traditional Chinese Medicine,Anhui Hefei 230041,China);Clinical Observation on Treatment of Bile Duct Syndrome after Laparoscopic Cholecystectomy with Therapy of Integrative Traditional Chinese and Western Medicine[J];Journal of Anhui Traditional Chinese Medical College;2010-02
China Proceedings of conference Full-text Database 7 Hits
1 ;Efflect of Astragalus mongholicus on proliferation and apoptosis in hormone sensitive(MCF-7)breast cancer cell lines with TAM[A];[C];2011
2 ;The Experimental research of LingQiJuanGan Liquor's Protection Effects Against the Acute Liver Injury and Anti Liver Fibrosis Effects on Rat[A];[C];2007
3 Jin Zhe-xiong,Qu Zhong-yuan(Pharmaceutical College,Harbin University of Commerce,Harbin 150076,China);Studies on the preparation technology and quality control standard of total eleutheroside tablet[A];[C];2008
4 Qv Zhong-yuan,Jin Zhe-xiong,Ling Xi(Pharmaceutical College,Harbin University of Commerce,Harbin 150076,China);Study on the Antifatigue Effect of Eleutherosides[A];[C];2008
5 ZHANG Jing-ze SHI Zuo-qing Department of Pharmacy, Medical College of Chinese People's Armed Police Forces, Tianjin 300162 The State Key Laboratory of Functional Polymeric Materials for Adsorption and Separation, Institute of Polymer Chemistry, Nankai University,Tianjin 300171;The study of purification of flavonoids from Hippohae rhamnoides L.on the coordination adsorption[A];[C];2006
6 CHEN Li-hua~1 FENG Yi~2 XU De-sheng~2 1.Key Lab for Modem preparation of TCM,Ministry of Education of China;Jiangxi university of Traditional Chinese Medicine,Nanchang 330006,China 2.Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;Survey in study on active components of Chinese materia medica to eczema[A];[C];2007
7 Yu wu-zhong,Gao guo-sheng,He xing-sheng,et al.Department of Nephrolog,the Central Hospital of EZhou,Xuzhou,Hubei,436000,China;A clinical study of the efect of astragale injection on serum lipids in nephrotic syndrome patients[A];[C];2009
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 TAO Da-yong (College of Animal Science and Technology,Tarim University,Alar,Xinjiang 843300);Immunomodulation Effect of Lycium barbarum Polysaccharide[J];Journal of Anhui Agricultural Sciences;2007-22
2 YE Ze-bing1, WANG Fan-jun2, ZHANG Gang-qing1, YANG Wang-min1, QIN Hai-sen1, LIU Xing-tao1 1Department of Emergency Medicine, Guangdong Second Provincial People's Hospital, Guangzhou 510317, China; 2Guangzhou Kingmed Clinical Laboratory Center, Guangzhou 510330, China;Effects of Astragalus Membranaceus Injection on TNF-α-induced release of inflammatory factors from HUVECs and the molecular mechanisms[J];Journal of Southern Medical University;2009-06
3 LIU Hong (Dept.of Pharmacology,Hubei Institute for Nationalities,Enshi 445000);Effects of Ligustrazini on Nitric Oxide,Endothelin and Lipidperoxidation in Experimental Atheroscierotic Rabbits[J];Journal of Hubei Institute For Nationalities Medical Edition;2000-04
4 YIN Wen qing 1, CHEN Qi 2, SHE Zhi gang 3 (1.Department of Chemistry and Chemical Engineering,Guangxi Normal University,Nanning,Guangxi 541004;2.School of Life Sciences, Zhongshan University;3.Guangdong College of Pharmacy);Effects of berberine chloride on LPS induced adhesion of human leucocyte with human umbilical vein endothelial cells[J];Academic Journal of Guangdong College of Pharmacy;2002-02
5 Ling Hoang, et al (Department of Pathophysiology, Hubei Medical College, Wuhan, China);The Effects of Trichosanthes and Propranolol on Aggregation and TAX_2 Generation of Platelet in Vitro[J];;1988-02
6 MA Lingjun,CHEN Qunli,YANG Wubiao,XI Shoumin,WAN Xuedong,TANG Xiaoming,YU Yanni,KANG Jian Department of Biochemistry and Molecular Biology,Medical College, Henan University of Science and Technology,Luoyang 471003;Effect of lycium barbarum polysaccharide against atherosclerosis in rabbits[J];Journal of Zhengzhou University(Science Medical);2005-02
7 JIANG Yi-deng1,CAO Jun1,DONG Quan-zhou1,WANG Shu-ren2(1.Department of Pathophysiology,Ningxia Medical College,Yinchuan 7500042,China;2.West China School of Basic Medical and Forensic,Sichuan University,Chengdu 610041,China);Anti-atherosclerosis potency by Lycium seed oil and its possible mechanism of PKC and MMPs[J];West China Journal of Pharmaceutical Sciences;2007-01
8 DUAN Hao,ZHANG Hongkao,LIU Jijun,et alThe Affiliated People's Hospital of Yunyang Medical College,Shiyan 442000,China;Effect of Berberine on IL-6 of Carotid Artery after Ballon Injury in Rabbits[J];Journal of Medical Forum;2006-10
9 Mei Jiajun,Cai Dayong,Zhao TingxiuHubei College of TCM,Wuhan 430061;Study of the Effective Mechanism Which Chinese Herb Ligusticum Chuanxiong Hort Prevents and Cures the Pathological Changes of Rabbit Atherosclerosis[J];Journal of Hubei College of Traditional Chinese Medicine;2004-02
10 DU Guan-hua (Institute of Materia Medica, CAMS & PUMC, Beijing 100005, China);Mechanism of endothelial cell injury and the drugs protection ofendothelial cell against injury[J];Basic Medical Sciences and Clinics;2004-03
【Secondary Citations】
Chinese Journal Full-text Database 3 Hits
1 HAO Yu,QIU Quanying,WU Jun (Department of Immunology,Beijing University of Chinese Medicine,Beijing 100029,China);Effect of astragalus polysaccharin(APS)on lymphocyte-endothelium adhesion and the molecular mechanism[J];IMMUNOLOGICAL JOURNAL;2000-03
2 DONG JIAN-WEN; SHI AN-YUN(Department of Pathophysiology, Beijing Medical University, Beijing 100083);PROTECTION OF SUPEROXIDE DISMUTASE ON HYPOXIA-REOXYGENATION INJURY TO ENDOTHELIAL CELL[J];ACTA PHYSIOLOGICA SINICA;1997-06
3 Wang Deqing Shen Wenmei Tian Yaping Sun Zhongyi Jiang Chaoguang Yuan Shimin(Department of Biochemistry,General Hospital of PLA,Beijing 100853);The Protective Effect of Active Components Extracted from Radix Astragali on Human Erythrocyte Membrane Damages Caused by Reactive Oxygen Species[J];China Journal of Chinese Materia Medica;1996-12
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