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《Carcinogenesis,Teratogenesis & Mutagenesis》 2009-04
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Acute Toxicity and Genotoxicity of Bioactive Peptide Powders

ZHOU Wen,LI Hui,CHEN Min (Disease Prevention and Control Center of Shandong,Ji,nan 250014,China)  
BACKGROUND AND AIM: To study the safety of bioactive peptide powders.MATERIALS AND METHODS: Acute toxicity test of mice,Ames test,micronucleus test of bone marrow PCE cell in mice,sperm shape abnormality test of mice were used.RESULTS: Bioactive peptides revealed a LD5010 g/kg in mice.The results of genetic toxicity test were all negative,including Ames test,micronucleus test and sperm shape abnormality test.CONCLUSION: The bioactive peptide powders was a substance with no toxicity and no genotoxicity under our experimental conditions.
【CateGory Index】: R114
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