Studies on the adsorption of bilirubin in solution by chitosan
WU Gang,SHEN Yu-Hua,XIE An-Jian,LIN Hong-Yun(College of Chemistry and Chemical Engineering, Anhui University, Heifei230039,China)
Chitosan can be used as the blood adsorbent because of its good biologic compatibility. The influence of temperature, pH value, human serum albumin (HSA) and ionic intensity on chitosan's adsorbability for bilirubin was studied in this paper. The result showed that HSA and NaCl could prevent from the adsorption of chitosan for bilirubin. In the given temperature range, raising temperature could fasten adsorptivity velocity and enhance adsorbability of chitosan. Being close to pH value of blood in human body, the chitosan has the good adsorbability for the uncombined bilirubin.