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《Journal of Anhui University(Natural Sciences)》 2005-02
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Effect of polysaccharide from the Gastrodia elata Blume on metabolism of free radicals in subacute aging model mice

KONG Xiao-wei~(1,2),LIU Ting-yi,GUAN Jian (1.School of Life Science,Anhui University,Hefei 230039,China; 2.Anhui Key Laboratory of Eco-engineering and Bio-technique,Hefei 230039,China)  
To study the effect of polysaccharide from the Gastrodia elata Blume (GEP) on metabolism of free radicals in subacute aging model mice.The activities of SOD,CAT and the contents of MDA in serum and tissues were measured,and the activity of GSH- Px in serum was measured.The results showed that the dosage of 300mg/kg GEP significantly increased the activities of SOD and CAT in serum and tissues (P0.01), and remarkably inhibited the formation of MDA in serum and tissues.In the meantime,GEP significantly increased the activity of GSH- Px in serum.These results demonstrate that the polysaccharide from the Gastrodia elata Blume possess the reliable function of eliminating free radicals and inhibiting the formation of MDA and delaying cell aging.
【Fund】: 安徽省教育厅自然科学研究基金资助项目(2004kj021)
【CateGory Index】: R285.5
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