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《Journal of Anhui Agricultural Sciences》 2007-18
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Research Progress in the Histone Acetylation/Deacetylation and Gene Expression and its Regulation

LI Bao-hua et al(College of Life Science,Henan Normal University,Xinxiang,Henan 453007)  
Nucleosome constitutes chromation is a basic unit in eucaryote.Histones are important components of nucleosome and their modifications of acetylation and deacetylation play an important role in gene expression and its regulation in eucaryote.Abnormally acetylated histones,including hyperacetylation and hypoacetylation,usually lead to the foul-up of gene expression,furthermore,they arouse diseases.The types of histone acetyltransferases and deacetylases,the relations of histone acetylation/deacetylation,gene expression and its regulation were summaried and described briefly.
【Fund】: 河南省动物学省级重点学科基金项目
【CateGory Index】: Q75
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