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《Journal of Anhui Agricultural Sciences》 2007-35
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Study on the Antioxidation of Polysaccharide from Sweet Potato

TIAN Chun-yu et al (College of Environment and Life Science,Dalian University of Technology,Dalian,Liaoning 116024)  
Objective The aim of the research was to discuss the scavenging mechanism of polysaccharide from sweet potato(PSP)on active oxygen free radicals.Method With the isolated and purified PSP as test materials,the chemical model systems were used to produce and ·OH.resp.And the scavenging capability of PSP on free radicals,its inhibition effect on pyrogallol autoxidation and the effects of PSP on SOD activity and MDA content in tumor-bearing mice were studied.Result In vitro,PSP both had scavenging effects on O2-· and ·OH and it had a positive correlation with the PSP concentration.In vivo,the antioxidation of PSP had a close correlation with the antitumor effect.PSP could increase the activity of serum SOD and reduce MDA content in tumor-bearing mice significantly.Conclusion PSP had stronger antioxidant capacity.Its antioxidant mechanism was scavenging free radicals and reducing MDA content mainly through strengthening the activities of antioxidases such as SOD.
【CateGory Index】: S531
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