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《Journal of Anhui Agricultural Sciences》 2008-10
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Study on the Effects of Sophora alopecuroides L.on the Immune Function of Mice

LI Li et al (College of Life Science,Henan Normal University,Xinxiang,Henan 453007)  
[Objective] The research aimed to explore the effect of Sophora alopecuroides L.on mice's immune function and provide certain reference basis for the development of herd immunosuppressant.[Method] Eight-week-old Kunming mice divided into 3 groups(high-concn.group,middle-concn.group and low-concn.group) were continuously given medicine through intragastric infusion with the daily dose of 5,10,15 g/kg for 7 day.Mice infused 0.5 ml/d drinking water were taken as control group.In the lymphocyte transformation test and the conventional HE staining test,the effects of Sophora alopecuraides L.decoction on the proliferation rate of lymphocytes and tissue structure of spleen in mice were studied.[Result] Compared with control group,the proliferation rates of T and B lymphocytes in mice after being treating with S.alopecuraides decoction at 3 concn.were both extremely significantly decreased(P0.01).The density of B lymphocytes in red pulpses of spleen in mice after being treating with S.alopecuraides decoction at middle and low concn.was obviously decreased,among which that with S.alopecuraides decoction at middle concn.was smallest.[Conclusion] S.alopecuraides decoction could decrease the proliferation of lymphocytes the density of B lymphocytes in red pulpses of mice spleen.So it had effects on the immune clearance function of spleen.S.alopecuraides had certain inhibitory effects on the immune function of mice.
【Fund】: 河南省科技攻关项目(0524420040);; 河南省动物学省级重点学科基金资助
【CateGory Index】: R285
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【References】
Chinese Journal Full-text Database 1 Hits
1 Ma Xiuxia1,Xu Liran2 Henan College of Chinese Medicine,Zhengzhou,Henan,China 450008 The First Affiliated Hospital of Henan University of TCM,Zhengzhou,Henan,China 450000;Konwledge of the Immune Function Light of TCM with Pulmonary Infection[J];China Journal of Chinese Medicine;2010-06
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 Wang Baokui;Yang Junji;Liu xijun;et al (Fuzhou General Hospital,Nanjing Military Command of PLA,Fuzhou)Ruan Jingchuo,Feng Ya (Fujian lnstitute of Traditional Chinese Medicine,Fuzhou);Blood Rheology Indexes of Rabbits Affected by Yiguan Capsule[J];STRAIT PHARMACEUTICAL JOURNAL;1999-01
2 Chen Jianji,Wu Zhiqiang, (Fujian Medical University,Laboratory of Snake Venom Research 350004) Hu En,Lin Zhiwei et al (Fujian Colloege of Traditional Chinese Medicine 350003);Studies on the Pharmacological Effects of the Polysaccharides of Ganoderma Lucidum Ⅰ.Anticancer,Antithrombosis and anticoagulation of blood[J];STRAIT PHARMACEUTICAL JOURNAL;2000-01
3 Hong Huawei,Qiu Songping,Wang Biping,Lin Jingyu(Institute of Traditional Chinese Medicine of Fujian,Fuzhou,350003);A Study of Pharmacological Effects of DouShiJiang In Pi deficiency Mice[J];STRAIT PHARMACEUTICAL JOURNAL;2000-02
4 WANG Shao ming,RUAN Jun shan,ZHUANG Jie,JIANG Qing ju(The Pharmacy Department of Fujian Provincial Hospital,Fuzhou 350001);The Effect of Xiaofu Oral Liquid on Antiinflammation,Sedation and Acute Toxicity Test[J];STRAIT PHARMACEUTICAL JOURNAL;2000-03
5 LI Sheng gang,YANG Xiao feng,YU De zhi ZHU Ai min(Qingdao institute for drug control P.R.China,Qingdao 266071);Effects of Piyundan on Gastrointestinal and Immunologic Function in Normal and Deficiency of Spleen’s mice[J];STRAIT PHARMACEUTICAL JOURNAL;2000-03
6 TANG Zu qing,CHEN Bang shu(Guangxi Institue for Drug Control,Nanning 530021);The Preliminary Study of Medicine Effect of Pearl Bright Eyedrop[J];STRAIT PHARMACEUTICAL JOURNAL;2000-03
7 WU Qiao-jin (Nanping Chinese Medicine Hospital,Nanping 353000)HUANG Mei-xing, LIN Dan-hong,XIE zhen-jia (New Drug pharmacological Research Centre, Fujian Health School, Fuzhou 350001);Experiments on Pharmacological Effects of the Pianzihuang Runhou Pian[J];Strait Pharmaceutical Journal;2001-01
8 LIU Zhi fang 1 WANG Xiu min 2 WANG Qing chuan 2(1.Fuzhou Hospital for Infectious Diseases 350025;2.Fujian Institute of Snake Toxin 350001);The Effect of Fulong Shezhi Liquid on White Blood Cells[J];Strait Pharmaceutical Journal;2001-03
9 WANG Li ying(The Ist people hospital of Changzhou, Jiangsu, Changzhou 213003);Study on Hepatic Protection and Decrease of Enzyme of Erzhi Pill[J];Strait Pharmaceutical Journal;2002-01
10 LI Ming 1,LIN Jian 2,ZHANG Rong biao 2,LIU Shao juan 2(1 Fujian lnstitute for Drug Control,Fuzhou,350001;2 Fujian Anti epidemic Centre,Fuzhou,350001);Effect of Runtong Capsule on Moistening the lntestines and Freeing the Stool in Mouse[J];Strait Pharmaceutical Journal;2002-03
China Proceedings of conference Full-text Database 10 Hits
1 ;Study on the Functional Effect of Chufa Functional Component[A];[C];2004
2 TANG Hong-mei1, QIU Zhen-wen1 ,LI De-tang2, KUANG Zhong-sheng2,YAN Xue2 (1 The First Affiliated Hospital of Guangzhou University of TCM ,Guangzhou 510405,china; 2 Guangzhou University of TCM ,Guangzhou ,510405,china);Mechanism Research of Changjian Fang Intervention on SP and CGRP in Model Rats of Diarrhea-Irritable Bowel Syndrome[A];[C];2010
3 Li Jing1,Zhu Yi2,Chen Guo-biao1,Huang Ling1 (1.Dept.of Pharmacology,Chongqing University of Medical Sciences,Chongqing 400016,China;2.Dept.of Pharmacology,the Institute for Drug Control of Hainan Province,Haikou 570216 China);Study on Antidiarrheal Effects of Total Flavonoids from the roots of Pongamia pinnata[A];[C];2007
4 CHU Mei-na~1,ZHU Yi~2,Yang Jia~1 (1.Chongqing Univercity of Medical Sciences,Chongqing 400016,China.2.Hainan Provincial Institute for Drug Control,Haikou 570216,China);Analgesic and Anti-inflammatory Effects of Total Alkaloids from Stephania hainanensis H.S.Lo et Y.Tsoong and it's Acute Toxicity Study[A];[C];2010
5 Siriguleng Zhang - Shuyu Temuer (Inner Mongplia Medical College, Hohhot 010059 China);Study of the sudorific effect of the daoguleebusi - 7 capsule[A];[C];2006
6 Feng Jian-hua,Mu Yan-ling,Xu Shu-lan,Zhu Yan,Cui Shu-xiang (Shandong Academy of Medical Scienses, Jinan, 250062);Protective effects of naomaixin granule on experimental cerebral ischemia in rats[A];[C];2005
7 LI Bao-qiu , WANG Ge, ZHAO Hua, ZHAO Yan-biao, (Toxicology Research Department of SDU, Jianan 250014, China; Shandong Yuanlong Biotechnology Co., Ltd, Jinan 250010, China; Shandong Hongli Laboratory Animal Experiments Co., Ltd, Jinan 250101, China);Rapid dissolution affects of recombined reteplase on blood clots induced in vivo[A];[C];2005
8 ;小儿解热栓的药理筛选[A];[C];2006
9 LI Wen-xia1, YAN Yan2, CHEN Zhong-guang2, CONG Ren-huai2, YE Xiao-chuan2*(1 Department of Chemistry, 2 College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074,China);Study on Anti-inflammatory effects and mechanism of activity sections of Smilax china L.[A];[C];2006
10 ZHANG Ling ZHANG Dao-ying DUN Zhu LIU Ya li [Key Laboratory of Modern Preparation of TCM,Ministry of Education(Jiangxi University of TraditionaL Chinese Medicine)Jiangxi Nanchang 330004 Tibetan Traditional Medicine college,Xizang Lasa 850000];The Anti-inflammatory and Analgesic Effects of Tibetan Drug Pyrethri tatsienensis[A];[C];2007
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 Fang Shumei,Zhang Hongwei,Qin Xuegong(College of Life Science and Technology,Heilongjiang Bayi Agricultural University,Daqing 163319);The Inhibition on Matrine to Human Lung Carcinoma LTEP-a-2 Cells Line was Determined by MTT Colorimetric Assay[J];Journal of Heilongjiang Bayi Agricultural University;2009-05
2 LI Li,LI Qian,ZHANG Shun-li(College of Life Sciences,Henan Normal University,Xinxiang 453007,China);Immunoregulation Effect of Sophora alopecuraides L.in Mice[J];Journal of Henan Normal University(Natural Science);2008-03
3 Cheng Shufeng No.1 Affiliated Hospital to Henan College of Chinese Medicine,Zhengzhou,Henan,China 450000;Dicussion of Treating Children Chronic Cough from Lung Spleen and Kidney[J];Journal of Chinese Medicine;2009-06
4 Liang Qijun(Postgraduate in Grade 2007,Hubei College of Traditional Chinese Medicine,Wuhan,Hubei,430065);Macroimmune Principle of Human Body and Zhang Zhongjing's Clinical Diagnostic Objective[J];Henan Traditional Chinese Medicine;2008-07
5 CHEN Wen-juan,YANG Min-li~*(Key Laboratory of Energy Sources Chemical Engineering,Ningxia University,Yinchuan 750021,China);Study of the volatile oil from different parts of Sophora alopecuroides L.in Ningxia by GC-MS[J];West China Journal of Pharmaceutical Sciences;2006-04
6 WAN Chuan-xing,LIU Ming-yue,SUN Hong-zhuan,LIU Wen-jie,ZHANG Li-li ( Key Laboratory of Protection & Utilization of Biological Resources in Tarim Basin of Xinjiang Production and Construction Groups, Tarim University,Alar,Xinjiang,843300 P. R. China);Qualitative and quantitative analyses of 13 constituents of alkaloids from Sophora alopecuroides by GC-MS[J];West China Journal of Pharmaceutical Sciences;2009-06
7 LUO Xing-Ping ①②③,NIE Ling-Yun④,ZHAI Zong-De ①②,XU Pei-Yuan③,CHEN Li-Ren,LI Yong-Min (①Lanzhou Institute of Chemical Physics,The Chinese Academy of Sciences,Lanzhou 730000,Gansu China) (②The Graduate School of Chinese Academy of Sciences,Beijing 100039 China) (③Gansu Province Institute for Drug Control,Lanzhou 730000,Gansu China) (④Institutute for Drug and Instrument Control of PLA,Beijing 100071 China);Simultaneous Determination of Three Alkaloids in Compound Kudouzhi Injection by Capillary Electrophoresis[J];Pharmaceutical Journal of Chinese People's Liberation Army;2005-06
8 Jin Ying; Liu Xiaojuan; Zhao Yanjie; Liu Wanzhu(Jinzhou Medical College)Wang Xiaodong; Wang Yanhua(The First Affiliated Hospital, Jinzhou Medical College);PROTECTIVE EFFECTS OF SOPHORAMINE ON ACUTE INJURY OF MYOCARDIAL ISCHEMIA IN ANESTHETIZED RATS[J];JOURNAL OF JINZHOU MEDICAL COLLEGE;1994-01
9 Li Shenghu1,He Shenghu2(1.Ningxia Professional Technical College,Yinchuan 750002,China;2.School of Agriculture,Ningxia University,Yinchuan 750021,China);Research of toxicity of alkaloids from Sophora alopecuroides[J];Journal of Agricultural Sciences;2009-01
10 WENGLing) (LIUYan) LIUXue ying) ,ZHANGYing) , ZHAOLin ai) (LEUKaren);Effect of Astragalus polysaccharide on cytokine secretion of murine sple nocytes and NK activity of S-180-bearing mice[J];Immunological Journal;2003-03
China Proceedings of conference Full-text Database 1 Hits
1 ZHOU Yi1, WANG He2, Liang Lei1,DENG Hongzhu1(1.the School of TCM; 2.Department of Hematology ,Nanfang Hospital, Southern Medical University ,Guangzhou 510515);Effects of total base of Sophora alopecuroides on expression of Foxp3 Tregs in rats with experimental colitis[A];[C];2006
【Secondary References】
Chinese Journal Full-text Database 4 Hits
1 Yang Zhende1 Zhao Boguang2 (1.College of Forestry, Guangxi University Nanning 530004; 2.College of Forestry Resources and Environment, Nanjing Forestry University Nanjing 210037);Effects of Alkaloids from Sophora alopecuroides on Oviposition Behavior of Plagiodera versicolora[J];Scientia Silvae Sinicae;2013-01
2 ZHANG Cheng-mei1,ZHANG Cheng-e2,XIN Qing3,WU Chuan-tao1,YIN Zhi-sheng1,YU Xue-hui1,LIU Zhao-ping1(1.Laboratory Animal Center of Shandong University,Jinan 250012,China; 2.Department of Supravital,Jinan Central Hospital Affiliated to Shandong University,Jinan 250013,China;3.School Hospital of Shandong University,Jinan 250012,China);Effects of Shenqi Fuzheng Injection Powder on immune function of mice[J];Journal of Shandong University(Health Sciences);2010-08
3 XIANG Yan-hong1,WANG Hao-yun2,YANG Ming-jun1,WANG Yong-gang1,LIU Xiao-feng1,(1.School of Life Science and Engineering,Lanzhou University of Technology,Lanzhou 730050,China;2.Lanzhou No.1 Middle School,Lanzhou 730000,China);Study on optimization of ultrasonic-assisted extraction of alkaloids from Sophora alopecuroides by response surface analysis[J];Science and Technology of Food Industry;2012-07
4 ZHU Gui-hua,YANG Jin(School of Chemistry and Chemical Engineering,Beifang University of Nationalities,Yinchuan 750021);Separation of alkaloids from sophora alopecuroides L.by high speed counter-current chromatography[J];Food Science and Technology;2011-12
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