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《Journal of Anhui Agricultural Sciences》 2009-03
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Study on Inhibitory Effect of Compound Polysaccharides from Spirulina Platensis on Human Mammary Cancer 231 Cell

YU Lei-yan et al (College of Life Science,Qiaodao Agricultural University,Qiaodao,Shandong 266109)  
[Objective] The study aimed to study the inhibitory effect of compound polysaccharides from Spirulina Platensis on human mammary cancer 231 cell.[Method] The polysaccharides from Spirulina Platensis(PSP) was compounded with the effective ingredients of Ginkgo Biloba(EGB) at some ratio to observe the inhibitory effect of compound preparation on human mammary cancer 231 cell.[Result] Compared with the blank control group,the compound preparation groups of PSP and GBE at the ratio of 1∶1,1∶2 and 2∶1 had the inhibitory rate on human mammary cancer 231 cell at high dosage was increased by 93.32%,57.83% and 44.95%,that at middle dosage was increased by 67.52%,59.93% and 41.72% and that at low dosage was increased by 54.22%,48.56% and 40.26%.It was found that the single ingredient of PSP had the better inhibitory effect on human mammary cancer 231 cells,but its inhibitory effect was decreased gradually with the reduction of the dosage.[Conclusion] The compound PSP had higher inhibitory effect on human mammary cancer 231 cell and its best inhibitory effect was in high dosage group of compound preparation at the ratio of 1∶1,showing that the cooperation and synergism of compound PSP reached maximum at this dosage matching.
【Fund】: 青岛农业大学高层次人才启动基金(630432);; 青岛市科技局项目(06-2-2-12-jch)
【CateGory Index】: R285;R737.9
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