Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Anhui Agricultural Sciences》 2009-05
Add to Favorite Get Latest Update

Detection on the Residues of Lincomycin in Honey by LC-ESI-MS/MS

RUAN Xiang-chun et al (College of Animal Sciences,Anhui Agricultural University,Hefei,Anhui 230036)  
[Objective] The purpose was to set up the method of detecting the residues of lincomycin in honey by HPLC-ESI-MS/MS.[Method] The samples purified by solid-phase extraction and isolated by liquid-phase extraction were analyzed by MS.The signal collection of characteristic maternal ions and sub-ion pairs was conducted in MRM.The qualitative analysis was conducted on the basis of retaining time,maternal ions and the two characteristic sub-ions.The quantification was conducted on base-peak ion m/z126,whose ion peak was most intense.[Result] In the linear scope of 1.0-20.0 ng/ml,the peak-intensity had good linear correlation with added concn.(r20.999 6).Under the 3 addition levels of 2.5, 5.0 and 10.0 ng/g,the average recovery of lincomycin was(95.1±3.3)%,the RSD of determination results during one day was smaller than 5.3%,that between two days was smaller than 8.5%,with detection limit being 0.1 ng/g.[Conclusion] HPLCESI-MS/MS was a sensitive and precise method in detecting the residues of lincomycin in honey and met the requirements of residues analysis on lincomycin.
【CateGory Index】: S896.1
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 3 Hits
1 FAN Hui-min,WANG Zhong,WANG Li-qi,YE Yan-feng,HUANG Xian-hui,ZENG Zhen-ling(Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, College of Veterinary Medicine,South China Agricultural University,Guangzhou 510642,China);Pharmacokinetics of Lincomycin Hydrochloride and Spectinomycin Sulfate Suspension for Injection in Swine[J];Journal of South China Agricultural University;2012-02
2 HUANG Zhi-yong,XU Hong,HUANG Yan-ping(Institute of Atomic Energy Application,Jiangxi Academy of Agricultural Sciences,Nanchang 330200,China);Preliminary Study on Effect of Radiative Degradation on Quality Safety of Honey[J];Acta Agriculturae Jiangxi;2011-09
3 WANG Jian1,WANG Hong-bo2,HONG Li-ya1(1.Zhejiang Institute for Food and Drug Control,Hangzhou 310004,China;2.Zhejiang University of Technology,Hangzhou 3100014,China);HPLC-ESI-MS~n separation and identification of ten impurities in clindamycin palmitate hydrochloride drug substances[J];Chinese Journal of Pharmaceutical Analysis;2012-12
【Citations】
Chinese Journal Full-text Database 1 Hits
1 RONG Ying-Jun1 CHEN ShengLu1 CHEN Ji-Shuan2 SU Song-Kun1(1 Animal Science College of Zhejiang University,;Research Advances on American Foulbrood of Honeybee (Apis mellifera)[J];Apiculture of China;2006-08
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 PAN Xiao-cheng et al (Anhui Agricultural University,Hefei,Anhui 230036);Synthesis and Identification of Ofloxacin Artificial Antigen[J];Journal of Anhui Agricultural Sciences;2006-03
2 WANG Tian-you et al(College of Animal Science,Henan Institute of Science & Technology,Xinxiang,Henan 453003);Observation of Histological-Pathology in Weaned Pig with Iron Overload[J];Journal of Anhui Agricultural Sciences;2006-18
3 SUN Xue-feng et al (College of Animal Science and Technology,Northwest A & F University,Yangling,Shaanxi 712100);Susceptibility Testing of the Combination of Amikacin and Tilmicosin against Some Pathogenic Bacteria of Dairy Cow Mastitis[J];Journal of Anhui Agricultural Sciences;2006-23
4 LI Gui-lan (Zongzhai Veterinary Station of Huangzhong county in Qinghai Province, Huangzhong, Qinghai 811602);Study on the Composite Anaesthesia Effects of Ketamine and Propofol to Tibetan Dogs[J];Journal of Anhui Agricultural Sciences;2008-21
5 WU Su-xiao et al(Yingdong Bioengineering Institute,Shaoguan College,Shaoguan,Guangdong 512005);Post-antibiotic Effect of Ceftriaxone on Swine Escherichia Coli in vitro[J];Journal of Anhui Agricultural Sciences;2008-23
6 HU Ting-jun et al(College of Animal Science and Technology,Guangxi University,Nanning,Guangxi 530005);Effect of Podophyllum emodi Polysaccharide on Antioxidant Capacities in Immunosuppressed Mice[J];Journal of Anhui Agricultural Sciences;2009-07
7 ZHU Hui-nan et al(Qingdao Agricultural University,Qingdao,Shandong 266109);Efficacy of Ampicillin Suspension against Colibacillosis in Chicken[J];Journal of Anhui Agricultural Sciences;2009-33
8 GUO Jiao-jiao 1 YANG Hu 1 PAN Hong-yan 1 GONG Zhi-yong 1 LI Gu 2(1 College of Food Science and Engineering,Wuhan Polytechnic University,Wuhan Hubei 430023;2 Yangtze River Fisheries Research Institute,Chinese Academy of fishery Science);Study on Acute Toxicity of Enrofloxacin in Sturgeon[J];Modern Agricultural Sciences and Technology;2010-20
9 XIAO Han1,LI Pei-ying1,WANG Xing-sheng2,DU Jia-lin1,GE-kai1,XU Qian-ming1,WU Jin-jie1(1.College of Animal Science and Technology,Anhui Agricultural University,Hefei 230036,China;2.College of Medicine,Anhui Chinese Medicinal and Technical University,Hefei 230038,China);Study on Resistance Against Six Anti-coccidia Drug of the Mixed Coccidia Strains in Some Regions of Anhui[J];Journal of Anhui Science and Technology University;2008-01
10 ZHENG Ya rong,GUO Lei,YE Tao (Department of Internal Medicine,Shanghai Friendship Hospital,Shanghai 200052,China);Analysis of the clinical and cost efficacy of amoxycillin injection and capsule in treatment of lower respiratory tract infection[J];Journal of Bengbu Medicinae College;2002-06
China Proceedings of conference Full-text Database 10 Hits
1 HE Yan~1,LIU Zhi-chang~1,ZENG Dong-ping~1,SUN Yong-xue~(1*) (1 Laboratory of Veterinary Phamacology,South China Agric.Univ.,Guangzhou 510642);Serum Pharmacokinetics of Oxytetracycline in Cows with Endometritis[A];[C];2011
2 WANG Weihua ,WEI Xinjun ,NAN Haijuan ,ZHANG Yongsheng, YAN Zhenmin (Henan Institute of Science and Technology,Xinxiang 453003);Study of Different Methods on Synthesizing Sulfamerazine Immunizing Antigens[A];[C];2008
3 KONG Fan-lin, CHU Cong-jia, GUAN Xin-long, LUO Ci-jieYuxi city people's hospital, YuxiYunnan, 653100 China;The distribution and variation of antibiotic-resistance rate of 4544 strains Gram-negative bacilli isolated from clinical[A];[C];2005
4 XUE Hong-Yuan, LI Jing-Su, CAI Chang-Chun (Dep. of Pharmacology, Bethune International Peace Hospital, Shijiazhuang 050082, China 050082);Investigation and Analyses of the Usage of Antibacterials in 492 soldier’s Cases in Respiratory Department[A];[C];2010
5 (Xu Jingfeng ,XuLin, General Hospital of Beijing Military Command, Beijing 100700,China);The distribution of class Ⅰintegron in ESBLs and Study on resistant genotypes of ESBLs[A];[C];2009
6 JIANG Hai-yun(Jiangsu Xuyi County People’s Hospital, Xuyi 211700, China);Evaluation and Drug Use Analysis of 11000 Outpatient Prescriptions in our Hospital from January to November of 2008[A];[C];2009
7 LI Wei-qing ,LI Min,YAN Zu-you,HU Ying-jun,CHEN Xiang-feng, QI Guo-hua, Wang Fang, YING Qing-ru, HU Ya-ying, SHEN Yan-ya Department of Pharmacy,Surgery,Shanghai Second People's Hospital,Shanghai 200011,China;Comparison and Evaluation on The Results of Pre and Post Intervention of Prophylactic Antibiotics Drug Application During Perioperative Period of Clean Incision and Clean-Defiled Incision in 144 Cases[A];[C];2009
8 JIANG Hai-yun(Jiangsu Xuyi County People’s Hospital,Xuyi 211700,China);Evaluation and Drug Use Analysis of 11000 Outpatient Prescriptions in our Hospital from January to November of 2008[A];[C];2010
9 LI Wei -qing ,LI Min,YAN Zu-you,HU Ying-jun,CHEN Xiang-feng,QI Guo-hua,Wang Fang,YING Qing-ru,HU Ya-ying,SHEN Yan-ya Department of Pharmacy,Surgery,Shanghai Second People's Hospital,Shanghai 200011,China;Comparison and Evaluation on The Results of Pre and Post Intervention of Prophylactic Antibiotics Drug Application During Perioperative Period of Clean Incision and Clean-Defiled Incision in 144 Cases[A];[C];2010
10 Xu Jingfeng ,XuLin,(General Hospital of Beijing Military Command,Beijing 100700,China;The distribution of class Ⅰintegron in ESBLs and Study on resistant genotypes of ESBLs[A];[C];2010
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 Zhang Chuanhui et al (Department of Biologe of Anhui University);Study on External Factors'Influence on Amylase Activity in Honey[J];JOURNAL OF ANHUI AGRICULTURAL SCIENCES;1999-04
2 SUI Wu-Bin(Department of Chemistry,Zaozhuang College,Zaozhuang,Shandong 277101);Study on the Determination Method of the Residual Quantity of Multi-Organophosphorus Pesticides in Honey[J];Journal of Anhui Agricultural Sciences;2007-29
3 ZHANG Jia-qing et al (Business School, Jiangnan University, Wuxi, Jiangsu 214122);Analysis on Incomplete Information of Honey Industry in China[J];Journal of Anhui Agricultural Sciences;2008-08
4 ZHU Zhao-fu1,HAN Chang-shuan2(1.Suixi County Hospital;2.Anhui Predate Pharmaceutical Science & Technic Co.,Ltd.230022);Methodological study on the dissolution of roxithromycin tablets[J];Anhui Medical and Pharmaceutical Journal;2009-04
5 LUO Dong, WANG Zhang yang, XIA Pei yuan, DAI Qing, RAN Guang bing, PENG Bei (Department of Pharmacy, Southwest Hospital, Third Military Medical University, Chongqing 400038, China);Contents of the main ingredients in compound clindamycin phosphate solution detected by HPLC[J];Acta Academiae Medicinae Militaris Tertiae;2003-23
6 SHANG Ruo feng,HU Zheng ying,LUO Yong jiang,LIANG Ji lan, SHI Yan bin,ZHENG Ji fang,ZHANG Xin guo,LUO Chao ying (Lanzhou Institute of Animal Husbandry & Veterinary Pharmaceutics Science,Gansu,Lanzhou,730050,China);Study on Antibacterial Activity of Lincomycin Hydrochloride, Spectinomycin Sulfate and its Composition in Vitro[J];Progress In Veterinary Medicine;2004-01
7 WU Shi-rong~(1,2), LI Zhi-liang~(1,2), LI Gen-rong~1, YANG Sheng-xi~1 (1.College of Chemistry and Chemical Engineering, Chongqing University,Chongqing 400044,China; 2.College of Biological Engineering, Chongqing University, Chongqing 400044 ,China);Biological Mass Spectrometry for Macromolecules: Approaches and Applications[J];Journal of Chongqing University(Natural Science Edition);2004-01
8 ZHANG Hai-yan1,ZHANG Min2 (1.Analysis and Test Center of Jiangsu University,Zhenjiang 212013,China;2.School of Chemistry & Chemical Engineering of Jiangsu University,Zhenjiang 212013,China);Application of High Performance Liquid Chromatography-Mass Spectrometry Technology in Detection of Perfluorooctane Sulfonate and Related compounds[J];Analysis and Testing Technology and Instruments;2010-01
9 LIU Xiao-xia1,2,DING Li1,ZHANG Ying1,HUANG Zhi-qiang1 and CHEN Bo2(1.Hunan Academy of Inspection and Quarantine.Technology Center of Hunan Entry-Exit Inspection and Quarantine Bureau,Hunan Key Laboratory of Food Safety Science & Technology,Changsha 410004;2.Key laboratory of Chemical Biology & Traditional Chinese Medicine Research,Ministry of Education,Hunan Normal University,Changsha 410081);Determination of Spectinomycin residue in milk and dairy products by high performance liquid chromatography-tandem mass spectrometry[J];Chinese Journal of Analysis Laboratory;2010-08
10 GU Jing Kai 1 * , CHU Da Feng 1, ZHONG Da Fang 1,4 , LI Yan 2 ZHOU Hui 1, SHEN Jia Cong 3 (1. College of Life Science, 2. College of Chemistry, 3. Key Lab. for Supermolecular Structure and Spectroscopy, Jilin University, Changchun 130;Studies on the Electrospray Ion Trap Mass Spectra of SFZ-47 and Its Metabolites for a Novel Anti-inflammatory and Analgesic Agent[J];Chemical Research In Chinese Universities;2002-02
【Secondary References】
Chinese Journal Full-text Database 1 Hits
1 HUANG Xin;ZHANG Chao;ZHOU Cuilan;ZOU Wei;SU Weiwei;PENG Wei;School of Life Sciences,Sun Yat-sen University;Guangzhou Yipinhong Pharmaceutical Company Limited;;Analysis of Impurities in Clindamycin Palmitate Hydrochloride Dispersible Tablets Through UFLC-Q-TOF-MS/MS[J];Acta Scientiarum Naturalium Universitatis Sunyatseni;2014-04
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved