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《Journal of Anhui Agricultural Sciences》 2009-06
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Study on the Anti-bacterial Role of Paeonol-aminoethanol and 2,4-dinitrophenyl Hydrazone

XIAO Na et al(Institute of Chemistry and Environmental Science,Shaanxi College of Technology,Hanzhong,Shaanxi 723001)  
[Objective] The useful reference for the structure modification and use of paeonol was provided through the experiment.[Method] The orange osmanthus skin-traditional Chinese medicine being taken as raw material,the active ingredient-phenol was extracted with the method of steam distillation and then the derivative of paeonol-aminoethanol and 2,4-dinitrophenyl hydrazone was synthesized.The structural characterization of the derivatives carried out was identified and the test in the anti-bacterial role of three kinds of gram-negative and positive bacteria was done with the method of agar diffusion.[Results] The results showed that the compounds measured in the range of experimental concentration had the inhibitory effect on the tested material,especially for the stronger inhibitory effect on bacillus pumilus.[Conclusion] The qualitative test indicated that the compound had the antibacterial role and quantitative analysis and application were needed for further research.
【Fund】: 陕西理工学院教改项目(XJG0726)
【CateGory Index】: S482.2
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