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《Journal of Anhui Agricultural Sciences》 2009-07
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Mechanism and Application of RNA Interference

YU Ling et al(College of Horticulture and Landscape,Southwest University,Chongqing 400716)  
RNA interference(RNAi)is a kind of post-transcriptional gene silencing(PTGS) phenomenon.It degrades its homologous mRNA specifically in cell through extracorporeal synthetic or intracorporal double-stranded RNA(dsRNA) to make the corresponding gene silencing and obtain the aim of stopping the gene expression.Because of its advantages such as being efficient,specific and simple and so on,RNAi provided new thoughts and methods for intracellular gene expression research.So RNAi will be used widely in the future.The mechanism and the application researches of RNAi were summarized.
【Fund】: 国家自然科学基金“矮牵牛AGL15亚家族基因PMADS9的功能研究”(30671481)
【CateGory Index】: Q789
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【References】
Chinese Journal Full-text Database 3 Hits
1 CHEN Ruo-fei(Shenyang Institute of Chemical Tecnology,Shenyang 110142,China);RNA Interference Technique and Its Application[J];Animal Husbandry and Feed Science;2009-05
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【Citations】
Chinese Journal Full-text Database 1 Hits
1 SONG Xue-Mei1,YAN Fei2,DU Li-Xin1(1.National Center for Molecular Genetics and Breeding of Animal,Institute of Animal Sciences,CAAS,Beijing 100094,China;2.State Key Laboratory for Biology of Plant Diseases and Insect Pests,CAAS,Beijing 100094,China);Components and Assembly of RNA-induced Silencing Complex[J];Hereditas;2006-06
【Co-citations】
Chinese Journal Full-text Database 3 Hits
1 BAI Wei-bo,JING Hua-lan.Department of Forensic Pathology,Zhongshan Medical School,Sun Yat-sen University,Guangzhou 510080,China;The advances of RNA interference technology in viral myocarditis[J];International Journal of Internal Medicine;2008-05
2 Li-Tang Zhang1,Yi-Gang Wang1,Xin-Yuan Liu1,2(1Xin Yuan Institute of Medicine and Biotechnology,College of Life Science,Zhejiang Science and Technology University,Hangzhou 310018,China;2Institute of Biochemistry and Cell Biology,Shanghai Institutes for Biological Science,Chinese Academy of Science,Shanghai 200031,China);RNAa:A New Contra-standard Model for ncRNA Regulating Gene Expression[J];Chinese Journal of Cell Biology;2008-03
3 PENG Jie-Jun 1,2 ,YAN Fei 2 ,CHEN Hai-Ru 1 ,CHEN Jian-Ping 2 1.Plant Protection College,Yunnan Agricultural University,Kunming 650201,China; 2.Institute of Virology and Biotechnology,Zhejiang Academy of Agricultural Science,Hangzhou 310021,China;Progress of studies on Dicer structure and function[J];Hereditas;2008-12
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【Secondary Citations】
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