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《Journal of Anhui Agricultural Sciences》 2009-15
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Study on the Interaction between Aspirin and DNA by Spectrometric Method

LIU Wei et al(Hainan Key Lab.of Tropical Medicinal Herb and Chemistry,College of Chemistry and Chemical Engineering,Hainan Normal University,Haikou,Hainan 571158)  
[Objective]The research aimed to study the interaction mechanism between aspirin and DNA.[Method]The interaction of aspirin and DNA was studied using UV spectrometry and fluorescence spectrometry.The quenching mechanism of fluorescence of aspirin by DNA was discussed through Stern-Volmer equation.[Result]The results showed that there were strong interaction between aspirin and DNA.The binding constant was 2.17×106 L/mol at 25 ℃.The number of binding sites was 1.773 5.And aspirin binded with DNA in a mode of intercalative binding with the result of UV-VIS spectrum.[Conclusion]This study could provide important information for further study about the pharmacological activity of aspirin.
【Fund】: 海南省重点科技项目(070207);; 海南师范大学博士启动基金资助项目(103307);; 海南省教育厅项目(Hjkj2009-39);; 海南省有机化学重点学科开放基金
【CateGory Index】: R96
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【References】
Chinese Journal Full-text Database 4 Hits
1 KANG Qian-qian,ZHOU Guang-ming (Key Laboratory on Luminescence and Real-Time Analysis(Southwest University),Ministry of Education,School of Chemistry and Chemical Engineering,Southwest University,Chongqing 400715,China);Study on Amoxicillin and the Interaction with DNA by Spectrometric Methods[J];The Journal of Light Scattering;2011-04
2 KANG Qian-qian,ZHOU Guang-ming Key Laboratory of Luminescence and Real-Time Analysis(Southwest University),Ministry of Education,and School of Chemistry and Chemical Engineering,Southwest University,Chongqing 400715,China;Study of Aspirin and Its Interaction with DNA by Raman and UV Spectroscopies[J];Spectroscopy and Spectral Analysis;2012-03
3 LI Boran,WANG Yanwei,YANG Guangcan College of Physics and Electronic Engineering,Wenzhou University,Wenzhou,Zhejiang 325035,China;Single Molecular Analysis of the Interaction between Aspirin and DNA[J];Acta Biophysica Sinica;2013-04
4 LIU Hong;JIANG Wei;LIU Wei;YANG Huan-xing;WEI Ji-cong;QI Guan-jun;LEI Ai-na;ZHONG Qing;LIU Nan-nan;DENG Su-meng;WANG Kai-yue;Hainan Normal University,Haikou Key Laboratory of Topical & Special Medicine and Edible Plant in Research and Development;;Spectrometry on Interaction between Angelica keiskei Roots Flavone and DNA[J];Food Research and Development;2014-15
【Citations】
Chinese Journal Full-text Database 2 Hits
1 FENG Xi-Zeng;JIN RuiXiang;QU Yun; HE Xi-Wen;(Department of Chemistry,Nankai University,Tianjin,300071);Studies on the Ions' Effect on the Binding Interaction Between HP and BSA[J];CHEMICAL RESEARCH IN CHINESE UNIVERSITIES;1996-06
2 JIANG Zhi liang 1, LIU Shao pu 1, ZHAO Bao gang 2,CHEN Sa 1,and LI Jian 2 1 Institute of Environmental Chemistry, Southwest China Normal University,Chongqiang 400715,China 2 Department of Physics,Southwest China Normal University,Chong;Studies on the Resonance Nonlinear Scattering of Aqueous CoFe_2O_4 Nanoparticle[J];Spectroscopy and Spectral Analysis;2002-04
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 HU Nai-liang,CHEN Yan,YANG Jia-xiang,SONG Ji-mei,XU Ji-zhao(College of Chemistry and Chemical Engineering,Anhui University,Hefei 230039,China);Synthesis of the schiff base compound and analytical application for determination of trace mercury[J];Journal of Anhui University(Natural Sciences);2008-06
2 GAO Gui-zhen,LIU Xiao-yang(Biochemistry Analysis Laboratory,Suzhou College,Suzhou 234000,China);Study on the interaction between alizarin red S and chitosan by fluorescence method[J];Journal of Anhui University(Natural Sciences Edition);2010-04
3 ZHANG Jian-gang et al(College of Art and Science,Shanxi Agricultural University,Taigu,Shanxi 030801);Study on a New Detection method of Trace Starch Content[J];Journal of Anhui Agricultural Sciences;2009-26
4 LIU Wei et al(College of Chemistry and Chemical Engineering,Hainan Normal University,Key Laboratory of Tropical Medicinal Plant Chemistry of Hainan Province,Haikou,Hainan 571158);Research on the Interaction of Resveratrol and DNA[J];Journal of Anhui Agricultural Sciences;2009-28
5 ZHAO Xia et al(Laboratory of Clinical Veterinary,Shanxi Agricultural University,Taigu,Shanxi 030801);Research on the Influences of Lead Ions on the Conformation of Calf-thymus DNA by Fluorescence Probe Method[J];Journal of Anhui Agricultural Sciences;2009-34
6 Yang Zhonsheng Centre of Anlysis and Test;The Enhanced Eftect of Surfactant on Al~(3+)-Ferron Fluorescent System and It's Application[J];Journal of Anhui Normal University(Natural Science);1991-03
7 THNG Wei LIU Qi Central laboratory, Shandong Acadeny of Agricultural Sciences. Jinan 250100;Determination of tyrosine in grain proteins by fluorescence spectrophotometry[J];;1993-02
8 JIANG Yul,2, YAO Wu2,3,ZHANG Li2,GAO Feng2,WANG Lun*2 (1 Huaining Middle School of Anhui Province,Huaining,246100) (2 College of Chemistry and Material Science,Anhui Nonmal Univesity Wuhu,241000) (3Department of Chemistry of Huangshan College,Huangshan,245021);Study on Acridine Orange-phenosafranine Energy Transfer Systems and Its Application in the Determination of Nucleic Acid[J];Journal of Anqing Teachers College(Natural Science Edition);2003-02
9 WU He-zhen~1,JIANG Yu~2 (1.Anqing Vocational Technology College,Anqing 246003; 2.Huaining Middle School of Anhui Province,Huaining 246100,China);The Application of Fluorescein-phenosafranine Energy Transter System to the Determination of DNA[J];Journal of Anqing Teachers College(Natural Science Edition);2005-03
10 XIAO Hou-rong,WANG Zhong-feng,YANG Hong,WU Qian-qian,ZHANG Jie,CAI Jing-min (Department of Biological and Environmental Engineering,Hefei University,Hefei 230022,China);Studying on the Interaction Between Zn~(2+) and Polyphenol Oxidase from Apple[J];Journal of Anqing Teachers College(Natural Science Edition);2009-02
China Proceedings of conference Full-text Database 10 Hits
1 ZHAO Dongxin~a,YAO Yongfeng~a,LU Kui~(a,b*) (a Henan University of Technology,Zhengzhou 450001; b Henan Institute of Engineering,Zhengzhou 451191);Study on the Interactions Between NA or NA-Tyr-Tyr and ct-DNA by Spectrometry[A];[C];2011
2 LI Wei-hua, LIU Wen-qing, LIU Jian-guo, ZHANG Yu-jun, YANG Li-shu, ZHAO Nan-jing, DING Zhi-qun (Anhui Institute of Optics and Fine Mechanics, Chinese Academy of Science, Hefei 230031, China);Detection of dissolved organic matter in river by laser induced fluorescence[A];[C];2005
3 LV Ai-xing, LU Chun-hua, QIU Bin and CHEN Guo-nan (Department of Chemistry, Fuzhou University, Fuzhou 350002);Determination of nevirapine by fluorescence quenching[A];[C];2005
4 Kui Lu1, 2, Ming-Xiu Lv1, Dong-Xin Zhao1, Liang-Ru Yang1 1 School of Chemistry and Chemical Engineering, Henan University of Technology, Zhengzhou 450052 2 Henan Institute of Engineering, Zhengzhou 451191;Studies on the Interaction of L-Phenylalanine Dipeptide with ct-DNA[A];[C];2008
5 LV Ming-xiu~1 ZHAO Dong-xin~1 LU Kui~(1,2*) 1 School of Chemistry and Chemical Engineering, Henan University of Technology, Zhengzhou (450001) 2 Henan Institute of Engineering, Zhengzhou (451191);Spectroscopic Studies on the Interaction of Phenylalanine Dipeptide with Calf Thymus DNA[A];[C];2008
6 ZHANG Ling-Fei~1 ZHENG Xiang-Yong~1 ZENG Xi~1 MU Lan~(*1) Yamato Takehiko~2 (1 Key Laboratory of Macrocyclic and Supramolecular Chemistry of Guizhou Province;School of Chemistry and Chemical engineering,Guizhou University,Guiyang 550025,P.R.China 2 Department of Applied Chemistry,Faculty of Science and Engineering,Saga University,Honjo-machi 1,Saga-shi,Saga 840-8502,Japan.);The Properties of A Nitrogen Heterocyclic Type Rhodamine-Based Thiacalix[4]crown Chemosensor[A];[C];2010
7 LU Kui~(*1,2) NIU Le-Peng~1 MA Li~1 ZHAO Dong-Xin~1 YAO Cheng-Cheng~1 (1 School of Chemistry and Chemical Engineering,Henan University of Technology,Zhengzhou 450001;2 Henan Institute of Engineering,Zhengzhou 451191);Studies on the Interaction of YKYY with DNA by Fluorescence Spectroscopy[A];[C];2010
8 Zhang Fang~1,Shi Yongsheng~2,Shi Xiaofan~1 (1 China Criminal Police University,Shenyang 110854;2 Technology Section of Inner Mongolia Province Wuyuan County Public Security Bureau,Inner Wuyuan Mongolia 015100);The Analysis of The Bark Extracts by the Synchronous Fluorescence Spectroscopy Method[A];[C];2011
9 Wu Jinxiu~1,Li Mei~1,Song Yumin~2,Liu haogang~1,Hu Yanhong~1 (1 College of Rare earth,Inner Mongolia University of Science and Technology,Baotou 014010,) (2College of Chemistry and Chemical Engineering,Northwest Normal University,Lanzhou 730070);Studies on the Interaction between Eu(Ⅲ) Complexes of Rutin with Human Serum Albumin[A];[C];2009
10 AODENG Gao-wa,WANG Xiao-xia~* College of Chemistry and Chemical Engineering,Inner Mongolia University,Huhhot 010021,China;Studies on the Interaction between Phenylbutazone,Copper(Ⅱ) and Protein by Fluorometry[A];[C];2010
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 LI Shu-feng(School of Physics & Information Engineering,Liaocheng University,Liaocheng 252059,China);Analysis of Theoretical Mechanism Model on Surface Enhanced Raman Spectrum[J];Journal of Anqing Teachers College(Natural Science Edition);2008-01
2 CAO Li-li,ZHU Dan,TIAN Tian,WANG Hai-tao,HUANG Ning-ping,XIAO Zhong-dang(State Key Laboratory of Bioelectronics,School of Biological Science andMedical Engineering,Southeast University,Nanjing Jiangsu 210096,China);AFM study on the interaction between DNA chain and small molecule drugs[J];Journal of Chinese Electron Microscopy Society;2011-02
3 Bai Li-tao,Zhang Li-ping,Zhao Guo-wen(Department of Materials and Chemical Engineering,Sichuan Institute of Science and Technology, Zigong,Sichuan643000,China);Development and Application of Raman Technology[J];Fujian Analysis & Testing;2011-02
4 LI Jian-qing1,WEI Yan-li2,DONG Chuan2(1.Jingzhong College,Jingzhong 030600;2.Environmental-science andEngineering-study Center,Shanxi University,Taiyuan 030600);Study on the Interaction between Berberin and DNA by Spectroscopy Methods[J];Journal of Analytical Science;2010-01
5 WANG Shu\|Ling, YU Jun\|Sheng\+* (Department of Chemistry, Nanjing University, Nanjing 210093, China);SERS Studies on the Interaction of Berberine With ct DNA[J];Chemical Research In Chinese Universities;2002-09
6 FENG Xi-Zeng;JIN RuiXiang;QU Yun; HE Xi-Wen;(Department of Chemistry,Nankai University,Tianjin,300071);Studies on the Ions' Effect on the Binding Interaction Between HP and BSA[J];CHEMICAL RESEARCH IN CHINESE UNIVERSITIES;1996-06
7 DONG Li-Hong WU Xiaa(Huaian Higher Vocational School of Biological Engineering,Huaian,Jiangsu 223200,P.R.China)a(School of Chemistry and Chemical Engineering,Shandong University,Jinan 250100,P.R.China);Interaction of 1-Naphthlcetic Acid with DNA by Spectroscopy[J];Chinese Journal of Spectroscopy Laboratory;2011-02
8 PU Xiao-Hua ZHANG Xin-Li ZOU Li-Wei GAO Hu-Jun(Department of Chemistry and Chemical Engineering,Baoji University of Arts and Sciences,Baoji,Shaanxi 721013,P.R.China);Interaction of Two Novel Schiff Base with DNA by Spectroscopy[J];Chinese Journal of Spectroscopy Laboratory;2011-02
9 MA Feng-ru,LIU Kun,ZHANG Yi,PAN Shi*(Institute of Near-field Optics and Nanotechnology,Department of Physics,Dalian University of Technology,China,116023);A Novel Silver Colloid as Substrate for Detection of Single-molecular Level of R6G[J];The Journal of Light Scattering;2007-01
10 QIAN Xiao-fan 1,SHI Ying 1,ZHAO Jin-tao 2,and SHI Wei 3 1.Department of Electrical Technology and Applied Physics,Kunming University of Science and Technology,Kunming 650051,China 2.Engineering School of Material and Metallurgy,Kunming University o;Studies of Penicillins by Micro Raman Spectroscopy[J];Spectroscopy and Spectral Analysis;2002-01
【Secondary References】
Chinese Journal Full-text Database 2 Hits
1 MA Li1,ZHANG Ya-zheng1,LU Kui1,2(1.School of Chemistry and Chemical Engineering,Henan University of Technology,Zhengzhou 450001,China; 2.School of Material and Chemical Engineering,Henan Institute of Engineering,Zhengzhou 450007,China);The structure of BRC peptide and research methods of interactions of biological macromolecule with BRC peptide[J];Journal of Henan Institute of Engineering(Natural Science Edition);2013-01
2 LI Boran,WANG Yanwei,YANG Guangcan College of Physics and Electronic Engineering,Wenzhou University,Wenzhou,Zhejiang 325035,China;Single Molecular Analysis of the Interaction between Aspirin and DNA[J];Acta Biophysica Sinica;2013-04
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 Feng Xizeng.He Xiwen (Department of Chemistry,Nankai University,Tianjin 300071);Interaction of Metal Ions-Hematoporphyrin Under Physiological Condition by Ultraviolet Spectrophotometry[J];Chinese Journal of Analytical Chemistry;1993-11
2 Li Yuanfang; Huang Chengzhi; Hu Xiaoli (Institute of Environmental Chemistry, Southwest Nounal University, Chongqing 400715);The Principles and the Applications of Resonance Light Scattering Technique in the Research of Biochemistry and Bioanalysis[J];Chinese Journal of Analytieal Chemistry;1998-12
3 JIANG Zhi Liang , LI Fang, LI Ting Sheng, LIANG Hong(College of Chemistry and Life Science, Guangxi Normal University, Guilin 541004, China) [WT5HZ];The Relationship Between Resonance Scattering Intensity and the Size of Au Particles[J];Chemical Research In Chinese Universities;2000-10
4 WANG Ya Ting , ZHAO Feng Lin, LI Ke An , TONG Shen Yang [WT5”BX](Department of Chemistry, Peking University, Beijing 100871, China) [WT5HZ];Analytical Application of Light Scattering Probe of Organic Dyes[J];Chemical Research In Chinese Universities;2000-10
5 ZHANG Bao-Lin; WANG Wen-Qing; BAI Feng-Lian(Coordination Chemistry Institute of Nanjing University,State Key Laboratory of Coordination Chemistry, Nanjing, 210008) (Technical Physics Department of Peking University) (Institute of Chemistry,Chinese Academy;Studies on the Binding of Anthraquinones and Flavonoids to Human Serum Albumin[J];CHEMICAL RESEARCH IN CHINESE UNIVERSITIES;1994-03
6 HE Xi-WEn; FENG Xi-Zeng; ZHANG Gui-Zhu; YANG Wan-Long;YU Gui-Ying; SHI Hui-Ming(Department of Chemistry, Nankai University, Tianjin, 300071);Studies on the State of Hematoporphyrin(HP) in Physiological Condition Solution[J];CHEMICAL RESEARCH IN CHINESE UNIVERSITIES;1994-04
7 ZHONG Fu?xin, JIANG Zhi?liang, LI Ting?sheng, LI Fang, LIANG Hong (College of Chemistry and Life Science, Guangxi Normal University, Guilin 541004, P. R. China);PHOTOCHEMICAL PREPARATION OF GREEN SILVER AND YELLOW SILVER COLLOID AND THEIR RESONANCE SCATTERING SPECTROSCOPIC STUDY[J];Photographic Science and Photochemistry;2001-01
8 LING Shao ming,JIANG Zhi liang,BI Xian shu,and YI Xiang hui Institute of Material Science and Engineering, Guangxi Normal University,Guilin 541004,China;The Preparation of Ag/AgCl Nanoparticle and Its Resonance Scattering Spectroscopic Study[J];Spectroscopy and Spectral Analysis;2001-06
9 Jiang Zhiliang Institute of New Technology and Material,Guangxi Normal University,Guilin 541004;THE FRACTION FREQUENCY SCATTERING SPECTRA FOR AU CLUSTERS IN LIQUID[J];Acta Photonica Sinica;2001-04
10 Xie Ji- Yun Jiang Zhi- Liang (College of Chemistry and Life Science, Guangxi Normal University,Guilin 541004);Resonance Scattering Spectra of Orange Ulcer Germs[J];Acta Physico-chimica Sinica;2001-05
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