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《Journal of Anhui Agricultural Sciences》 2009-17
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Pharmacological Chemistry Test Study on Analgesic and Anti-inflammatory Effects of Compound Wild Ginseng Oral Liquid

CAO Jie-wei (Shangqiu Center of Animal Disease Control,Shanqiu,Henan 476000)  
[Objective] The aim was to provide the reference for clinical application of compound wild ginseng oral liquid.[Method] With Kunming white mice as the tested animal and treatment with normal saline as CK,the effects of intragastric administration with 25 ml/kg indomethacin and 2.5,5.0,10,20 g/kg compound wild ginseng oral liquid on writhing response and auricle swelling of mice were studied,the relationships of dose-effect and time-effect of compound wild ginseng oral liquid were investigated.[Result] The inhibition rates of 25 ml/kg indomethacin and 2.5,5.0,10,20 g/kg compound wild ginseng oral liquid on writhing times of white mice were 81.73%,33.65%,38.46%,50.48% and 76.73% resp and those on auricle swelling of white mice were 15.14%,6.23%,5.20%,18.20% and 27.22% resp.After 0,1,2,3,6.5 h of intragastric administration with 5.0 g/kg compound wild ginseng oral liquid,the incidence of writhing mice were 50%,50%,10%,10%,0 resp.[Conclusion] The analgesic effect of compound wild ginseng oral liquid was worse than that of indomethacin,but its inhibition on auricle swelling of white mice was better than that of indomethacin.
【CateGory Index】: R285
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