Effect of Foeniculum vulgare Mill on the Immunological Functions in Mice
DONG Hua-ze et al(Department of Chemistry and Chemical Engineering,Hefei Teachers College,Hefei,Anhui 230061)
[Objective] The research aimed to study the effects of Foeniculum vulgare Mill on the immunological functions of the immunosuppressive mice induced by cyclophosphamide(CTX).[Method] Cyclophosphamide was used to prepare the immunosuppressive mice model.Based on the pharmacology test in vitro,the phagocytosis rate of macrophage and the serum hemolysin antibody level in mice after stomach administration were determined.The proliferative response of T lymphocyte induced by phytohemagglutinin(PHA) was measured.The serum containing drug was used to culture peritoneal macrophage(Mф) in vitro.The activity of macrophage was studied by using MTT assay.The phagocytic percent and phagocytic index of chicken red blood cell by macrophage cultured in vitro were measured.[Result] F.vulgare improved the carbon particle clearance rate of the immunosuppressive mice,promoted the formation of serum hemolysin and promoted the proliferation of T lymphocyte.[Conclusion] F.vulgare could improve the immunological functions of mice.
【CateGory Index】： R285.5