Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Anhui Agricultural Sciences》 2009-28
Add to Favorite Get Latest Update

Research on the Interaction of Resveratrol and DNA

LIU Wei et al(College of Chemistry and Chemical Engineering,Hainan Normal University,Key Laboratory of Tropical Medicinal Plant Chemistry of Hainan Province,Haikou,Hainan 571158)  
[Objective]The basis of the information for the further study on the pharmacological activity of resveratrol was provided.[Method] The interaction between Resveratrol and DNA moleculein in the Tris buffer solution system with the pH value of 6 was studied with the fluorescence spectroscopy,UV technology and the viscosity method.The binding constant and binding site between the resveratrol and DNA were calculated. [Results]At 25℃,the binding constant and binding site between the resveratrol and DNA were 3.96×10~3 L/mol and 1.005 3,respectively. The binding way was the resveratrol embedded into DNA,which could be an important factor that the resveratrol may have anti-cancer efficacy and the resveratrol embedded into DNA affected DNA transcription and replication,resulting in apoptosis of cancer cells.[Conclusion]It was proved that the resveratrol was embedded into DNA,which could be an important reason that the resveratrol had the anti-tumor activity.
【Fund】: 海南省重点科技项目(070207);; 海南师范大学博士启动基金资助项目(103307);; 海南省教育厅项目(Hjkj2009-39);; 海南省有机化学重点学科开放基金
【CateGory Index】: R285
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 4 Hits
1 FENG Xi-Zeng;JIN RuiXiang;QU Yun; HE Xi-Wen;(Department of Chemistry,Nankai University,Tianjin,300071);Studies on the Ions' Effect on the Binding Interaction Between HP and BSA[J];CHEMICAL RESEARCH IN CHINESE UNIVERSITIES;1996-06
2 JIANG Zhi liang 1, LIU Shao pu 1, ZHAO Bao gang 2,CHEN Sa 1,and LI Jian 2 1 Institute of Environmental Chemistry, Southwest China Normal University,Chongqiang 400715,China 2 Department of Physics,Southwest China Normal University,Chong;Studies on the Resonance Nonlinear Scattering of Aqueous CoFe_2O_4 Nanoparticle[J];Spectroscopy and Spectral Analysis;2002-04
3 YU Yan-ying1, LI Hua1, HU Xin1, CAO Shu-wen21. Department of Chemistry, Nanchang University, Nanchang 330031, China2. Key Laboratory of Food Science of Ministry of Education, Nanchang University, Nanchang 330047, China;Research on the Interaction of Cr(Ⅲ) Complex of Genistein with DNA[J];Spectroscopy and Spectral Analysis;2008-07
4 ZHAO Yuan-Di PANG Dai-Wen WANG Zong-Li CHENG Jie-Ke (Department of Chemistry, Wuhan University, Wuhan, 430072) LUO Zhi-Feng FENG Chang-Jian SHEN Hao-Yu ZHANG Xiang - Cai (Department of Chemistry, Central China Normal University, Wuhan, 430070);Electrochemical Studies of Antitumor DrugsⅠ. Fundamental Electrochemical Characteristics of an Iron(Ⅲ) Schiff Base Complex and Its Interaction with DNA[J];Acta Chimica Sinica;1998-02
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 LIU Wei et al(Hainan Key Lab.of Tropical Medicinal Herb and Chemistry,College of Chemistry and Chemical Engineering,Hainan Normal University,Haikou,Hainan 571158);Study on the Interaction between Aspirin and DNA by Spectrometric Method[J];Journal of Anhui Agricultural Sciences;2009-15
2 XIAO Hou-rong,WANG Zhong-feng,YANG Hong,WU Qian-qian,ZHANG Jie,CAI Jing-min (Department of Biological and Environmental Engineering,Hefei University,Hefei 230022,China);Studying on the Interaction Between Zn~(2+) and Polyphenol Oxidase from Apple[J];Journal of Anqing Teachers College(Natural Science Edition);2009-02
3 ZOU Cai xia\+1, JIANG Zhi liang\+2, YIN Wen qing\+2 (1. City Construction School of Guangxi, Guilin 54100, China; 2. Department of Resource and Environmental Science, Guangxi Normal University, Guilin 541004, China);Studies on the Hypochromic Effect of Composite Nanoparticle of Toluidine Blue-Sodium Tetrabenboron[J];Analysis and Testing Technology and Instruments;2002-02
4 Liao Zuhe, Luo Yanghe, Jiang Zhiliang, Xie Jiyun(Department of Resource and Environmental Science, Guangxi Normal University, Guilin541004, China);Resonance Scattering Spectroscopic Study of Colibacillus[J];Analysis and Testing Technology and Instruments;2003-02
5 YUAN Wei-en, JIANG Zhi-liang(Institute of Material Science and Engineering, Guangxi Normal University, Guilin 541004,China);Spectral Properties of Some Nanoparticles in Liquid Phase andtheir Analytical Applications[J];Analysis and Testing Technology and Instruments;2004-04
6 Zhou Danhong, Feng Zhuofu, Zhang Wenwei, Yang Mei (Department of Chemistry, Liaoning Normal University, Dalian ll6029 );Study on the Aggregation of Methylene Blue in Aqueous Solution of Surfactant by Absorption Spectroscopy[J];Chinese Journal of Analytieal Chemistry;1997-08
7 Jiang Zhiliang *1 , Zou Jieming 2, Wang Lisheng 2, Qin Aimiao 1 1(Department of Resource and Environmental Science, Guangxi Normal University, Guilin 541004) 2(Guilin Sanjin Pharmaceutical Company Limited, Guilin 541004);Resonance Scattering Study on the Interaction between Proteins and Trichloroacetic Acid and Its Analytical Application[J];Chinese Journal of Analytical Chemistry;2003-01
8 Jiang Zhiliang 1,2, Meng Mianwu 1, Liu Shaopu 2 1(Department of Resource and Environmental Science, Guangxi Normal University,Guilin 541004) 2(Institute of Environmental Chemistry, Southwest-China Normal University,Chongqiang 400715);Resonance Rayleigh Scattering Spectroscopy of Yellow CdS Naoparticle[J];Chinese Journal of Analytical Chemistry;2003-03
9 Zou Jieming 1, Pan Hongcheng 2, Jiang Zhiliang 2, Yuan Weien 2, Wang Lisheng 1 1(Guilin Sanjin Pharmaceutical Company Limited, Guilin 541004) 2(Department of Resource and Environmental Science, Guangxi Normal University, Guilin 541004);Resonance Scattering Spectra Study on the Association Particle System of Berberine Hydrocholoride-Sodium Dodecylbenzene Sulfonate and Its Analytical Application[J];Chinese Journal of Analytical Chemistry;2003-11
10 Liu Yongming *, Li Guizhi, Sun Xifen (College of Chemistry, Yantai University, Yantai 264005);Study on the Interaction between Colchicine and Bovine Serum Albumins by Fluorescence Method[J];Chinese Journal of Analytical Chemistry;2004-05
China Proceedings of conference Full-text Database 7 Hits
1 JIANG Zhi-liang,ZOU Cai-xia,LIU Shao-pu (1. Department of Resource and Environmental Science,Guangxi Normal University.Guilin 541004.China; 2.City Construction School of Guangxi,Guilin 541004,China; 3. Institute of Environmental Chemistry,Southwest-China Normal University,Chongqing 400715,China);STUDIES ON THE FLUORESCENCE QUENCHING AND RESONANCE SCATTERING MECHANISM OF PMo-RDG COMPOSITE NANOPARTICLE SYSTEM[A];[C];2002
2 JIANG Zhi-liang,LIU Shao-pu,ZOU Cai-xia (1. Department of Resource and Environmental Science ,Guangxi Normal University ,Guilin 541004 ,China; 2. Institute of Environmental Chemistry .Southwest-China Normal University,Chongqing 400715,China: 3. City Construction School of Guangxi,Guilin 541003,China);STUDIES ON THE POLAROGRAPHIC QUENCHING EFFECT OF PdI_4-2MG COMPOSITE NANOPARTICLE SYSTEM[A];[C];2002
3 LI Fang,JIANG Zhi-liang (Department of Resource and Environmental Science,Guangxi Normal University .Guilin 541004 .China);STUDIES ON THE FLUORESCENCE QUENCHING MECHANISM OF [AuCl_4]-RDG COMPOSITE NANOPARTICLE SYSTEM[A];[C];2002
4 ZOU Cai-xia,YANG Ming-mei,JIANG Zhi-liang (1.City Construct School of Guangxi,Guilin 541003,China; 2. Department of Resource and Environmental Science ,Guangxi Normal University .Guilin 541004 .China);RESONANCE SCATTERING SPECTROSCOPIC STUDY OF THE COMPOSITE NANOPARTICLE OF ETHYL VIOLET-PMA HETEROPOLY[A];[C];2002
5 ZOU Jie-ming,WANG Li-sheng,JIANG Zhi-liang,YIN Wen-qing,QIN Ai-miao (1. Guilin Sajin Pharmceutical Company Group,Guilin 541004; 2. Department of Resource and Environmental Science,Guangxi Normal University,Guilin 541004,China);SPECTRAL STUDIES ON THE COMPOSITE NANOP ARTICLE SYSTEM OF CPFX-PHLO[A];[C];2002
6 WANG Li-sheng,YIN Wen-qing,JIANG Zhi-liang,ZOU jie-ming (1.Guilin Sajin Pharmceutical Company Group .Guilin 541004.China; . Department of Resource and Environmental Science.Guangxi Normal University.Guilin 541004.China );STUDIES ON THE FLUORESCENCE QUENCHING AND RESONANCE SCATTERING MECHANISM OF DBS-BRDB COMPOSITE NANOPARTICLE SYSTEM[A];[C];2002
7 Li Guizhi Liu Yongming (College of Chemistry,Yantai University,Yantai 264005,China);Study on the Interaction between Human Serum Albumins and Methyl Pheophorbide-a-Gd[A];[C];2007
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 Feng Xizeng.He Xiwen (Department of Chemistry,Nankai University,Tianjin 300071);Interaction of Metal Ions-Hematoporphyrin Under Physiological Condition by Ultraviolet Spectrophotometry[J];Chinese Journal of Analytical Chemistry;1993-11
2 Li Yuanfang; Huang Chengzhi; Hu Xiaoli (Institute of Environmental Chemistry, Southwest Nounal University, Chongqing 400715);The Principles and the Applications of Resonance Light Scattering Technique in the Research of Biochemistry and Bioanalysis[J];Chinese Journal of Analytieal Chemistry;1998-12
3 Wang Peng , Yuan Yi, Zhang Milin, Zhu Guoyi (Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry,Chinese Academy of Sciences, Changchun 130022) (Deparment of Chemical Engineering, Harbin Engineering University, Harbin 150001);Analysis of 2D-Nuclear Magnetic Resonance for Ru(2,2'-bipyridine)_2(4,4'-dimethyl-2,2'-bipyridine) (PF_6)_2[J];Chinese Journal of Analytical Chemistry;1999-06
4 JIANG Zhi Liang , LI Fang, LI Ting Sheng, LIANG Hong(College of Chemistry and Life Science, Guangxi Normal University, Guilin 541004, China) [WT5HZ];The Relationship Between Resonance Scattering Intensity and the Size of Au Particles[J];Chemical Research In Chinese Universities;2000-10
5 WANG Ya Ting , ZHAO Feng Lin, LI Ke An , TONG Shen Yang [WT5”BX](Department of Chemistry, Peking University, Beijing 100871, China) [WT5HZ];Analytical Application of Light Scattering Probe of Organic Dyes[J];Chemical Research In Chinese Universities;2000-10
6 KANG Jing-Wan~*, WU Hai-Xia, LU Xiao-Quan, SU Bi-Quan, ZHOU Lin (Department of Chemistry, Northwest Normal University, Lanzhou 730070, China);Synthesis and Characterization of Water-soluble Zinc Porphyrin Complex and Its Interaction with CT DNA[J];Chemical Research In Chinese Universities;2005-06
7 ZHANG Bao-Lin; WANG Wen-Qing; BAI Feng-Lian(Coordination Chemistry Institute of Nanjing University,State Key Laboratory of Coordination Chemistry, Nanjing, 210008) (Technical Physics Department of Peking University) (Institute of Chemistry,Chinese Academy;Studies on the Binding of Anthraquinones and Flavonoids to Human Serum Albumin[J];CHEMICAL RESEARCH IN CHINESE UNIVERSITIES;1994-03
8 HE Xi-WEn; FENG Xi-Zeng; ZHANG Gui-Zhu; YANG Wan-Long;YU Gui-Ying; SHI Hui-Ming(Department of Chemistry, Nankai University, Tianjin, 300071);Studies on the State of Hematoporphyrin(HP) in Physiological Condition Solution[J];CHEMICAL RESEARCH IN CHINESE UNIVERSITIES;1994-04
9 ZHONG Fu?xin, JIANG Zhi?liang, LI Ting?sheng, LI Fang, LIANG Hong (College of Chemistry and Life Science, Guangxi Normal University, Guilin 541004, P. R. China);PHOTOCHEMICAL PREPARATION OF GREEN SILVER AND YELLOW SILVER COLLOID AND THEIR RESONANCE SCATTERING SPECTROSCOPIC STUDY[J];Photographic Science and Photochemistry;2001-01
10 LING Shao ming,JIANG Zhi liang,BI Xian shu,and YI Xiang hui Institute of Material Science and Engineering, Guangxi Normal University,Guilin 541004,China;The Preparation of Ag/AgCl Nanoparticle and Its Resonance Scattering Spectroscopic Study[J];Spectroscopy and Spectral Analysis;2001-06
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved