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《Journal of Anhui Agricultural Sciences》 2009-31
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Immunization Efficiency of Swine Fever Live Vaccine (Spleen and lymph tissue origin),Swine Foot and Mouth Disease (Type O) Inactivated Vaccine,Porcine Reproductive and Respiratory Syndrome (PRRS) Inactivated Vaccine

DOU Peng-xun et al(College of Animal Medicine,Northwest A&F University of Science and Technology,Yangling,Shaanxi 712100)  
[Objective] The aim was to seek a new effective pattern of immune procedure in order to effectively control epidemic situation of classical swine fever(CSF),swine foot-and-mouth disease(FMD) and porcine reproductive and respiratory syndrome(PRRS) in Yulin district.[Method] In Hengshan and Mizhi County of Shaanxi Province,140 pigs were divided into 7 groups randomly,20 pigs in each group.In immune experiment,we applied CSF live vaccine(spleen and lymph tissue origin),FMD inactivated vaccine(type 0-Ⅱ) and PRRS inactivated vaccine(strain NVDC-JXA1) in style of punctiform infection with combinations of one,two and three of these three kinds of vaccines respectively and then detected with ELISA.[Result] ①CSF,FMD and PRRS three kinds of vaccines all could stimulate pigs to produce specific antibody and antibody titer increased regularly on the 21st,28th and 35th day.②When CSF,FMD and PRRS three kinds of vaccines applied separately and simultaneously,FMD and PRRS vaccines could affect rise time of CSF antibody,but effect for immune effectiveness generated was not obvious.③When PRRS and FMD inactivated vaccines were injected simultaneously,the valence positive rate of antibody generated on the 21st,28th and 35th day was higher than the one of PRRS injected only at the same day respectively,that illustrated FMD inactivated vaccine had the positive synergistic effect for generating antibody after injecting PRRS vaccine and promoted generating of effective PRRS antibody.The antibody level of applying FMD inactivated vaccine and PRRS inactivated vaccine simultaneously was lower than the one injected PRRS alone,that illustrated when injected CSF and PRRS vaccine simultaneously,they could effected each other and make immune effect decline.④The antibody level of FMD inactivated vaccine was highest and with tendency of rise when injected FMD and PRRS simultaneously.That was higher than the antibody level of injecting FMD inactivated vaccine alone,indicated that injecting FMD and PRRS simultaneously could promote the generation of FMD antibody.
【CateGory Index】: S858.28
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