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《Journal of Anhui Agricultural Sciences》 2009-33
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Efficacy of Ampicillin Suspension against Colibacillosis in Chicken

ZHU Hui-nan et al(Qingdao Agricultural University,Qingdao,Shandong 266109)  
[Objective] The research aimed to evaluate the curative effect of Ampicillin suspension against the chicken infected by coliform,and provide basis for clinical rational drug use.[Methods]The curative effect of Ampicillin suspension was tested in preventing the colibacillosis in Kebao Chicken through in vitro and in vivo experiments,and was compared the result with Ampicillin soluble powder.[Results]Vitro test results showed that:the minimal inhibitory concentration of E.coli by Ampicillin suspension and Ampicillin soluble powder were 1 μg/ml and 4 μg/ml.Vivo antibacterial trials indicated that:the mortality of Ampicillin suspension groups were lower than positive control group obviously,the difference was significant(P0.05-0.01).Compared the groups used Ampicillin Suspension and Ampicillin Soluble Powder,the cure rate and effective power were significantly increased,the mortality was significantly decreased,but there were no significant difference.Compared the groups used Ampicillin Suspension with the positive control group,the results in weight gain was significant difference(P0.01);the treatment groups used Ampicillin Suspension with the negative control group were significant difference(P0.05);the Ampicillin suspension groups and the Ampicillin Soluble Powder groups were significant difference(P0.05).[Conclusions] The Ampicillin suspension could be used for prevention and treatment of colibacillosis in chickens,the best dose to prevention was 30 mg/L and the treatment dose was 90 mg/L.
【CateGory Index】: S858.31
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1 SU Fen-li,XIONG Fen,TANG Hong-mei (Department of Pharmacy,The First Affiliated Hospital,Guangzhou University of Traditional Chinese Medicin e,Guangzhou 510405);Practice and experience for prescription comment in rational drug use[A];[C];2012
2 ZHANG Chun-Xia(Department of Pharmacy of Wuhan Wuchang Hospital,Wuhan 430063,China);The experience of application of evidence-based pharmacy in the clinical drug intervention[A];[C];2011
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5 Objective:Hepatic Branch hospital in the course of treatment of hepatitis B antiviral medication status and trends of drug use.Methods:DDDs (DDDS) analysis of the liver section in our hospital in June 2010 in June 2011 for the use of antiviral drugs and statistical analysis.Results:The hospital antiviral eight kinds of nucleotides,and interferon drugs distribution;DDDs analysis of lamivudine in our hospital is ranked first on the main use of antiviral drugs,adefovir dipivoxil,and the amount of DDDs in the use of three top ranking,analysis with satisfactory results;Pegylated interferon than widely used in our hospital.Conclusion:Hepatitis B nucleotide antiviral drugs in clinical use in the still dominant position;Pegylated interferon can eliminate the economic factors such as hepatitis B will become the dominant clinical use of antiviral drugs.HBV antivirals in clinical use by larger economic factors.;Analysis of Antiviral Drug Use in the treatment of Chronic hepatitis B of Our Hospital[A];[C];2011
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