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《Journal of Anhui Agricultural Sciences》 2010-25
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Primary Exploration on Antibacterial Active Part of Extract from Orostachys spinosa (L.) C.A. Mey

WANG Xiang-fei et al (Key Laboratory of Xinjiang Endemic Phytomedicine Resources,Ministry of Education/Pharmacy College,Shihezi University,Shihezi,Xinjiang 832002)  
[Objective]The research aimed to compare the in vitro antibacterial action of different extract fractions from Orostachys spinosa (L.) C.A.Mey.[Method]With O.spinosa as tested material,the in vitro antibacterial action of its different extract fractions were compared by using filter paper diffusion and double dilution methods.[Result]The sensitivities of different tested strains to extract from O.spinosa were different,among which Escherichia coli was most sensitive and Staphylococcus aureus was insensitive.The antibacterial effects of 95% ethanol extract and petroleum ether extract from O.spinosa on E.coli were obvious,their diameters of inhibition zones exceeded 15 mm and the antibacterial effect of petroleum ether extract was superior to that of 95% ethanol extract.The antibacterial effects of 95% ethanol extract and petroleum ether extract from O.spinosa on S.aureus were not obvious.The minimal inhibitory concn.of petroleum ether extract from O.spinosa on E.coli and S.aureus were 7.9 and 31.3 g/L resp.[Conclusion]This research provided experimental basis for extraction and separation of antibacterial active part from O.spinosa.
【Fund】: 石河子大学高层次人才启动项目(RCZX200666)
【CateGory Index】: S567.239
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