Study on Combined Hypoglycemic Effect of Wild Taraxacum mongolicum and Rhodiola sachalinensis on Diabetic Mice
YANG Yong-jie et al (Agricultural College,Yanbian University,Yanji,Jilin 133002)
[Objective] The aim was to study the combined hypoglycemic effect of wild Taraxacum mongolicum and Rhodiola sachalinensis in Changbai Mountain on diabetic mice.[Method] Thirty kunming mice were selected,among which 24 became diabetes model by man-made methods.Thirty mice were divided into five groups,including blank control group,alloxan group,Rhodiola sachalinensis group,wild Taraxacum mongolicum group and combined dose group.The mice in Rhodiola sachalinensis group,wild Taraxacum mongolicum group and combined dose group received intragastric administration of self-made water decoction for five days continuously,one time per day,and then their blood glucose were detected.[Result] The blood glucose of diabetic mice in each group all lowered five days after the intragastric administration,which had an extremely significant difference from the alloxan group(P0.01).[Conclusion] Rhodiola sachalinensis,wild Taraxacum mongolicum as well as the combined treatment of Rhodiola sachalinensis and wild Taraxacum mongolicum all had significant hypoglycemic effect on diabetic mice.