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《Journal of Anhui Agricultural Sciences》 2011-29
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Optimization of the Extraction Technology of Total Alkanoids from Radix Sophorae Tonkinensis with Ultrasonic Extraction Technology

YANG Fan et al(The Department of Chemistry,Changchun Normal University,Changchun,Jilin 130032)  
[Objective] The aim was to study the optimum extraction technology of total alkanoids from Radix Sophorae Tonkinensis.[Method] The total alkanoids from Radix Sophorae Tonkinensis were extracted with ultrasonic technology.The effects of ethanol concentration,material-liquid ratio,extraction time and extraction times were studied through single factor test.And the extraction technology of total alkaloids from Radix Sophorae Tonkinensis was optimized by using L9(34) orthogonal test.[Result] According to the results of single factor test,the optimum results of four examine factors were that the ethanol concentration was 40%,the ratio of material to liquid was 1∶25,the time of extraction was 2 h and the times of extraction was twice,the content of total alkaloids was the highest.According to the results of orthogonal test,the sequence of influential significance was as follows: ethanol concentration(A)extraction time(C)material-liquid ratio(B)extraction times(D),the optimum technology of ultrasonic extraction was that the ethanol concentration was 40%,the ratio of material to liquid was 1∶15,the time of extraction was 1.5 h and the times of extraction was twice;the total alkaloids content of the extraction from Radix Sophorae Tonkinensis was 16.713 7 mg/g.[Conclusion] This method optimized extraction technology of total alkaloids from Radix Sophorae Tonkinensis with ultrasonic extraction technology,and could be as the foundation for further research to total alkaloids from Radix Sophorae Tonkinensis.
【Fund】: 吉林省科技厅项目(20102203);; 吉林省教育厅项目(吉教科合字2010379);; 长春师范学院资助项目
【CateGory Index】: S567.19
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