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《Journal of Anhui Agricultural Sciences》 2014-11
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Study on Relationship of Human Ago2 Protein and Tumors

LIN Ai-qin;ZHAO Yue-hua;Department of the Medical Biology,Wannan Medical College;  
Argonaute2( Ago2) protein,the core of RNA-induced silencing complex( RISC),complexed with the guide strand of a small interfering RNA( siRNA) or a microRNA( miRNA) and ubiquitously expressed and binded to siRNAs or miRNAs to guide post-trascriptional gene silencing either by destabilization of the mRNA or by translational repression. It has important functions in processes as diverse as embryonic development,cell differentiation and tumor biogenesis.
【CateGory Index】: R730
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