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《Journal of Anhui Normal University(Natural Science)》 2005-02
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SYNTHESIS AND CHARACTERIZATION OF POLYMERIC DRUG CONTAINING NAPROXEN AND ITS NANO-MICROSPHER

SUN Li-lin,SUN Yu,SHEN Liang-jun (College of Chemistry and Materials Science,Anhui Normal University,Wuhu 241000, China)  
Abstrcat Naproxen,a nonsteroidal anti-inflammatory drug,was linked with 2-hydroxyethyl methacrylate (HEMA)through covalent linkage,the drug-linked HEMA(monomer)was homopolymerized and copolymerized to obtain polymeric drug.The polymeric nano-microspheres were prepared by emulsion polymerization.The influence factors on the polymerization were investigated. Synthetic products were characterized with~1H-NMR,GPC and TEM.
【Fund】: 安徽省教育厅自然科学基金项目(2002KJ119).
【CateGory Index】: TQ463.53
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