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《Journal of Anhui Health Vocational & Technical College》 2006-06
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Clinical significance of peripheral reticulocyte percentage in monitoring bone marrow suppression after solid tumor chemotherapy

Anhui Provincial Hospital,Hefei 230001,AnhuiWANG Gang1,WANG Ye-man2,JI Chu-shu1,HU Bing1  
Objective To investigate the significance of peripheral reticulocyte percentage(Ret%) in monitoring bone marrow suppression after solid tumor chemotherapy. Methods The neutrophils count and peripheral reticulocyte percentage were detected by SYSMEX XE-2100 Automated Hematology Analyzer in different days before and after chemotherapy.The data were analyzed by test and chi square test. Results The percentages of peripheral reticulocyte percentage(Ret%) in the solid tumor patients during chemotherapy decreased earlier than the amount of neutrophils.The ratio of grade IV bone marrow suppression was 71.4% in those Ret%≤0.3%,while that was 8.3% in those Ret%0.3%(the seventh day after chemotherapy),which showed statistical difference(P0.01). Conclusion The percentage of peripheral reticulocyte percentage is an effective index to predict the suppression of bone morrow hematopoiesis during solid tumor chemotherapy.
【CateGory Index】: R730.5
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