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《Journal of Anhui Health Vocational & Technical College》 2008-04
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Recent observation of clinical efficacy of domestic docetaxel combined with cisplatin in treatment with advanced non-small-cell lung cancer

Department of Oncology,Traditional Chinese Medicine Hosptial of Lu’an,Lu’an 237006,Anhui SUN Qing-ming,ZHANG Ai-ling,XU-bin  
Objective:To evaluate the short-term efficacy and toxicity of domestic docetaxel combined with cisplatin(DDP) in treatment with advanced non-small-cell lung cancer(NSCLC) patients.Methods:31 patients with advanced NSCLG were treated by DDP.All patients were received with at least two cycles of chemotherapy.Results:The total effective rate was 35.5%,the effective rate of Ⅲb stage patients was 50.0%,and Ⅳ stage was 26.3%.Whereas the significant difference existed between the native patients and the retreated patients(42.9% VS 20.0%,p0.05).The main toxicities included myelosuppression,、nausea and vomiting.The severities of these side effects were gradeⅠ\Ⅱand well tolerable.The rate of the most severiity of toxicities was 20.5%.Conclusion:The DDP was worth putting into use in the advanced non-small-cell lung cancer.
【CateGory Index】: R734.2
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