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《Journal of Anhui Health Vocational & Technical College》 2010-03
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Therapeutic effect of Edaravone on the 84 patients with acute Cerebral Infarction

Anhui Provincical Friendship Hospital,Hefei 230011,Anhui PENG Xiao-jiang  
Objective:To evaluate the clinical efficacy of Edaravone on the treatment of acute cerebral infarction.Methods:84 patients with acute cerebral infarction (ACI)were randomlydivided intotwogroups:the treatment group and the control group,42 cases in each group.Edaravone(30mg)was executed in treatment group besides the basic scheme to treat infarction for 14 days,and the latter was just executed in control group exclusively for 14 days.Before and 1d,7d,14d and 2ld after the therapy,neural function defect evaluation (NIHSS)and the Bathals: index (BI)were assessed;and than clinical curative effect were measured at prior treatment and post treatment in both groups.The liver and renal function,blood and urinaryroutine,lipid,glucose and electrocardiogram (ECG)were detected.Result There was a significant improvement of the outcome of NIHSS and BI in the two1groups.The treatment group had obvious amelioration at the 3rd daythan the control group byNIHSSand BI (P0.05),and exceedingsignificant difference at the 7th dayand the 14th day (P0.001).Clinical outcome of the two groups on the clinical curative efficacy was greatly improved.The treatment group was better than the control group (P0.05).Conclusions: Clinical efficacyin treatingACI with edaravone is significant and safety,which can significantlyreduce the mortalityand improve the neurological deficit.
【CateGory Index】: R743.3
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