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《Anhui Journal of Preventive Medicine》 2003-06
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Application of Antibody Detection to Diagnosis of Meningoencephalitis Caused by Mumps Virus

ZHAO Yue-ping 1, ZHOU Shu-jie 1, TANG Ji-hai 1, LUO Guang-tao 2,PAN Fu-long 2, XIA Zhi-cai 3, QIN De-qin 3 (1.Anhui Center for Disease Control and Prevention, Hefei, Anhui, 230061, China;2.Ningguo Sanitaion and Anti-epidemic Station,Ningguo,Anhui,242300,China; 3.Xuancheng Center for Disease Control and Prevention,Xuancheng,Anhui,242000,China)  
Objective To analyze value of IgM antibody detection to diagnosis of meningoencephalitis caused by mumps virus. Methds 356 cases of mumps occurred in the period from April to August, 2003 in Ningguo county were investigated. Of them, 83 cases were diagnosed as meningoencephalitis. Serum and CSF samples of 23 meningoencephalitis cases were detected for IgM antibody of mumps virus with ELISA. Results 273 mumps cases had typical symptoms and signs of mumps. Vaccination history of most meningoencephalitis cases was not clear. Only 15 meningoencephalitis cases were accompanied by typical mumps symptoms and signs. Half of serum samples (6/12) and 2 of 13 CSF samples were positive for IgM antibody of mumps virus. Conclusions The results indicated that IgM antibody detection was of reference value for diagnosis of meningoencephalitis caused by mumps virus.
【CateGory Index】: R446.6
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