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《Anhui Journal of Preventive Medicine》 2013-05
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Study on the surveillance of Adverse Event Following Immunization with vaccine in Wuhu,2010~2012

WANG Si-yin;YU Xiu-nian;Wuhu Center for Disease Control and Prevention;  
Objective To study the occurrence features of Adverse Event Following Immunization(AEFI) in Wuhu,evaluate the implementation of AEFI surveillance system,the safety of vaccines and the quality of immunization services,and explore AEFI prevention measures.Methods The AEFI data in 2010-2012 were collected through China Information System for AEFI,the descriptive methodology was used in this study.Results 308 AEFI cases occurring in 2010-2012 were reported including 257 cases with common vaccine reaction(83.44%),49 cases with rare vaccine reaction(15.91%),2 cases with coincidental event(0.65%).The AEFI report coverage rate in counties was 100.00%,the AEFI report coverage rate in vaccination clinics was 93.55%; the reported rate within 48 h were 97.40%,the investigated rate within 48 h were 100.00%.81.82% of cases occurred within 1 d after vaccination.Children aged 0-2 years old and 6 years old accounted for 89.94%.The fever,redness,swelling,induration and anaphlaxis dominated the clinical diagnosis of AEFI cases.The AEFI incidence rate were 12.10/100 000,of which the common vaccine reaction incidence rate were 10.10/100 000,the rare vaccine reaction incidence rate were 1.93/100 000.85.06% of cases occurred among the national immunization program(NIP) vaccine,69.81% of cases occurred among the first dose of vaccination; the vaccines reported more vaccine reaction following immunization were DTaP(39.29%),DT(15.26%),A+C MCV(7.79%),PPV23(5.19%),MR(4.87%); the common vaccine reaction incidence rate and rare vaccine reaction incidence rate of NIP vaccine were not significantly different than second type of vaccine.Conclusion At present,the operation status of AEFI surveillance system of Wuhu city was good,AEFI surveillance were more sensitive.
【CateGory Index】: R186
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