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《Anhui Medical Journal》 2001-02
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Significance of determination of urine microprotein for diagnosing early renal disease in patients with diabetes mellitus

Wang Danging ,Lin Bin,Li Hua Department of laboralory,Anhui Provincial Hospital,Hefei 230001  
Objective To discover early renal disease of diabetes mellitus (DM) by determining three microproteins in random urine.Methods Urine microproteins were detected by the method of immunoturbidimetry.Urinary creatinine was measured using colorimetry.Results The levels of urinary MA/Cr,TRF/Cr and α 1-MG/Cr in urinary albumin negative group were (3 500±2 780)mg/mmol,(0 337±0 289)mg/mmol,(3 185±2 980)mg/mmol respectively.The levels in the controls were (0 608±0 178)mg/mmol,(0 152±0 091)mg/mmol,and (0 872±0 443)mg/mmol respectively.There was marked difference between two groups (P0 01).Conclusions The urinary MA,TRF and α 1-MG can be used as sensitive and reliable indexes for early renal disease of DM.
【CateGory Index】: R446.121
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