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Observation on airway pathological histology and superminusular strueture in the rats with Pulmonary Qi Deficiency Syndrome

Dou Hongman, Wang Yuanxun, Cai Shengrong,et al Dept of Pathology, the First Affiliated Hospital of Anhui Traditional Chinese Medical College, Hefei 230031  
Objective To explore the guantitive indexes of airway changes of the rats with pulmonary qi deficiency syndrome and the basic gualities of the syndrome, we made the observtion of airway pathological histology in rats with pulmonary gi deficiency syndrome and the Superminuscular structure. Methods 50 Wistar rats were randomly divided into control group and model group. Model rats were made by using smoke and injecting LPS into trachea, 0.9% Nacl were injected into trachea in control rats. Airway pathological observation indexes and evaluation methods were used to analyze the differences between two groups.Results The symptoms of the rats in model group accorded with the gualities of pulmonary qi deficiency syndrome. Changes of airway pathological histology and superminuscalar structure demonstrated pathological changes of chronic bronchitis and pulmonary emphysema, The thickness of the trachea wall and trachea glandes of the rats in model group was obviously higher than that in control group, so did the pathology scores of airway pathological change. The above differences were significant. Conclusion A qantitive method of pathological shape measuement and pathological observation indexes can be used for airway pathological changes with pulmonary qi deficiency syndrome.
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