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《Anhui Medical Journal》 2009-06
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The observation of the curative effect of Nimodipine to vascular cognitive impairment post stroke

Wang Qingyin,Wang Qingzhu, Zheng Jinshu, et al Department of Neurology, the Second People's Hospital,Chuzhou 239001  
Objective To investigate the curative effect of Nimodipine to vascular cognitive impairment (VCI) post stroke. Methods One hundred thirty three (132) stroke patients were enrolled. All the enrolled patients were randomly chosen and divided into a prevention group and a control group, with 63 cases in the prevention group and 69 cases in the control group. In each group the incidence of the original were routinely treated with guidelines of neurology. The course of treatment ran for 2-4 weeks. The prevention group took Nimodipine tablet orally 30mg ever eight hours. And the duration of administration was 6 months. MMSE used to estimate the therapeutic effect. Resealts Compared with the control group, the prevention group increased the MMSE scores significantly (P0.05). Conclusion Early intervention treatment by taking Nimodipine tablet orally is effective for VCI post stroke.
【CateGory Index】: R749.1
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