Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Anhui Medical and Pharmaceutical Journal》 2006-01
Add to Favorite Get Latest Update

Proliferation inhibition of TGP on SMMC-7721 Cell in vitro

WANG Shi-hong~(1,2),WEI Wei~(1),XU Du-juan~(1),XU Shu-ping~(1),CUI Ying~(2)(1.Institute of Clinical Pharmacology,Anhui Medical University;Anhui Key Laboratory of Antiinflammatory and Immunopharmacology;Anhui Provincial Key Laboratory of R&D of Chinese Medicine,Hefei 230032;2.He'nan College of TCM,Zhengzhou 450008)  
Aim To study the proliferation inhibition of different concentrations of total glucosides of paeony(TGP) on human hepatoma cell SMMC-7721. Methods The proliferation inhibitory effect of TGP on tumor cells was assayed by MTT method.The morphologic changes of the human hepatoma cell SMMC-7721 was observed by staining with acridine orange(AO)fluorescent dyes.Results TGP(0.5~2.5 g·L~(-1)) had inhibitory effect on the proliferation of SMMC-7721 with the concentration-dependence.AO dying showed TGP induced typical chromatin condensation in SMMC-7721 cells.Conclusion TGP can inhibit the proliferation of SMMC-7721 cells in vitro and induce its apoptosis.
【CateGory Index】: R735.7
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 1 Hits
1 LI Xiao-dong1,CHEN Xiao-wen2,LIU Hua-feng2,TANG De-shen2,LIANG Dong2 (1.Department of Nephrology,Tangshan Worker's Hospital,Tangshan 063000;2.Institute of Nephrology,Guangdong Medical College,Zhanjiang 524001);Effect of aldosterone and its receptor antagonist on proliferation of cultured rat mesangial cells[J];Anhui Medical and Pharmaceutical Journal;2007-02
【Citations】
Chinese Journal Full-text Database 4 Hits
1 Cai Yuwen,Li Yulan,Zhao Lei,et al(285);Eeffet of glucosidorum Paeoniae Alba on exzymatic actirity of lymphocytes in experimental liver cancer[J];LIAONING JOURNAL OF TRADITIONAL CHINESE MEDICINE;1999-06
2 Wei Wei, Liang Junshan Zhou Aaiwu et al (The clinical Pharmacology Institute, Anhui Medical University, Hefei );EFFECTS OF TOTAL GLUCOSIDES OF PAEONY ON INTER-LEUKI'N 2 PRODUCTION[J];Chinese Pharmacological Bulletin;1989-03
3 XU Du Juan, WEI Wei, XU Shu Yun ( Institute of Clinical Pharmacology, Anhui Medical University, Hefei 230032);The relationship of between the pineal gland and cell immunity and the influence of TGP[J];CHINESE PHARMACOLOGICAL BULLETIN;1997-04
4 YAN Xueshen, LI Hanmin, PENG Yaqin, et al. Hospital Affliated to Hubei College of TCM (Wuhan, 430061);Effects of Paeoniflorin on Proliferation of Human Hepatocarcinoma Cell Strain Bel-7402[J];Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases;2001-05
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 YANG Shi You, HUANG Shi Fu,SUN Bei,TIAN Jun (Anhui Institute of Pharmacy,Hefei 230022 );Effect of beishao jieyu granules in depression model mice[J];Anhui Medical and Pharmaceutical Journal;2004-02
2 ZHAO Bin,GE Jing-fang,LI Jun(School of Pharmacy,Anhui Medical University,Hefei 230032,China);Advances in studies on the anti-tumor mechanisms of camptothecin[J];Anhui Medical and Pharmaceutical Journal;2006-01
3 XU Bai ping*, HUANG Guo xian, HU Pi li, et al Departments of Traditional Chinese Medicine and Intervention, Cancer Center, Sun Yat sen University of Medical Sciences, Guangzhou 510060, P R China;Study of prevention and treatment of the syndrome after the liver cancer transcatheter arterial chemoembolization with the method of Qingre Rougan[J];CHINESE JOURNAL OF CANCER;2000-08
4 Wang Xiaozhen Li Ning Wang Lühua Li Yexiong Department of Radiotherapy,Cancer Hospital,CAMS & PUMC,Beijing 100021,China;Advances in clinical research of malignant pleural mesothelioma[J];Oncology Progress;2006-01
5 LI Jiang-hua~1,ZHAO Gui-bao~2,TANG Chang-fa~2(1.South China Normal University,Guangzhou 510631,Guangdong China;2.Physical Education Institute of Hunan Normal University,Changsha 410012,Hunan China);The Action of Adipocytokines in Regulating Organisms' Energy Metabolism and Fat Accumulation[J];Journal of Beijing Sport University;2006-10
6 WANG Xiao-ming~1,LI Fu-biao~2,LU Wen-wei~3,CHEN Xia~(3)(1.Department of Cardiology,First Hospital,Jilin University,Changchun 130021,China;2.Department of Urology,First Hospital,Jilin University,Changchun 130021,China;3.Department of Pharmacology,School of Basic Medical Sciences,Jilin University,Changchun 130021,China);Protective effects of total glycosides of Pacony on acute myocardial ischemia in dogs[J];Journal of Jilin University(Medicine Edition);2006-03
7 Li Yongjian et al ( Shanghai University of TCM );Clinical Epidemiological Investigation and Research of Syndrome Distribution Law in Chinese Medicine of 2060 Cases of Primary Liver Carcinoma[J];China Journal of Traditional Chinese Medicine and Pharmacy;2003-03
8 TANG Xin sheng, SUN Shi liang, LI Jian, et al. (Department of Radiation Oncology, Chongqing Tumor Hospital, Chongqing 400030,China);Analysis of the treatment effects of radiotherapy for the local advanced hepatocellular carcinoma[J];Chongqing Medical Journal;2002-05
9 CHEN Jing,ZHANG Su-hua,DU Juan,et al.(1.Department of Hypertension and Endocrinology,Third Military Medical University,Chongqing 400042,China;2.Department of Endocrinology,First Affiliated Hospital,Chongqing University of Medical Sciences,Chongqing 400016,China);Changes of blood glucose,serum lipids,leptin and the levels of hypothalamic leptin in diet-induced obese rats[J];Chongqing Medicine;2006-09
10 SHI Peng Department of Nephrology, PLA 451 Hospital, Xi'an 710054, China;Effects of total glucosides of paeony on active Heymann nephritis in rats[J];Journal of The Fourth Military Medical University;2005-18
【Secondary References】
Chinese Journal Full-text Database 3 Hits
1 REN Feng-lian,QU Bai-lu and TAN Xiao-yan(College of Chemistry and Chemical Engineering,Central South University,Changsha 410083);Determination of total glucoside content of paeony in Paeonia lactifloria Pall.by Alkaline hydrolysis-UV spectrophotometry[J];Chinese Journal of Analysis Laboratory;2008-10
2 SHOU Dan,ZHONG Honglang,GAO Jiajian,et al;TO DETERMINE THE CONTENT OF SALVIANOLIC ACID B IN TIAOGANHUAYU PARTICLES BY RP-HPLC[J];Modern Hospital;2008-11
3 LU Yutang1,XU Huazhong1,ZHOU Jinwen21(The Second Compulsory Detoxification Center of Zhuhai PublicSecurity Bureau,Zhuhai,519000,China)2(Tianda Pharmaceuticals(Zhuhai)LTD,Zhuhai,519070,China);EFFICACY OF YI'AN DECOCTION FOR PROTRACTED WITHDRAWAL SYMPTOMS IN HEROIN DEPENDENT PATIENTS[J];Chinese Journal of Drug Dependence;2009-06
【Secondary Citations】
Chinese Journal Full-text Database 8 Hits
1 Cai Yuwen,Li Yulan,Zhao Lei,et al(285);Eeffet of glucosidorum Paeoniae Alba on exzymatic actirity of lymphocytes in experimental liver cancer[J];LIAONING JOURNAL OF TRADITIONAL CHINESE MEDICINE;1999-06
2 Wang Li-qian et al (Pharmaclolgical and Toxicollgical Research Centre, Shanghai University of TCM, Shanghai 200032);STUDY ON ANTITUMOR ACTIVITY OF THE SOPHORA FLAVESCENS AIT AND AGRIMONIA PRLOSA LEDEB BY METHOD OF SERUM PHAMACLOLGY[J];Chinese Journal of Traditional Medical Science and Technology;1995-05
3 Wei Wenshu,Wang Youqi& Wang Yushan et al ( The Clinical Pharmacology Institute of Anhui Medical University, Hefei );IMMUNOREGULATORY EFFECTS OF TOTAL GLUCOSIDES OF PAEONY ROOT IN MICE[J];Chinese Pharmacological Bulletin;1987-03
4 GUO Hao,WEI Wei,CHEN Min-Zhu,XU Shu-Yun (Institute of Clinical Pharmacology,Anhui Medical University,Hefei 230032);Effects of total glucosides of paeony on T cell regulatory functions[J];Chinese Journal of Pharmacology and Toxicology;1993-03
5 Qi Xinguang, et al Dept. of Infecticus Diseases, The Third Affiliated Hospital;EFFECT OF DANSHEN AND CHISHAO ON PLASMA FIBRONECTIN IN PATS WITH EXPERIMENTAL LIVER DAMAGE[J];Journal of China Medical University;1990-03
6 Huang Kongwei et al Department of Pharmacology, Cancer Institute, Chinese Academy of medical Sciences, Beijing;Radix Paeoniae Rubra, Its Antitumor Activity on Experimental Tumors and the Effect of cAMP Content[J];Chinese Journal of Clinical Oncology;1985-03
7 Cai yuwen;et al(Dept. of Histology and Embryology, China Medical University);THE STUDY OF THE ENZYME ACTIVITIES IN LYMPHOCYTE ON THELYMPH NODE AROUND THE CANCER OF THE LIVER CANCER--The Electron Histochemical observation[J];CANCER RESEARCH ON PREVENTION AND TREATMENT;1994-01
8 Yu Yong-li Yang Gul-zhen (Bethune University of Medical Sciences,Chang Chun);The Effect of Ginsenoside(GS) on NKC-IFN-IL-2 Regulatory Network and It's Tumor Inhibiting Effect[J];Chinese Journal of Immunology;1987-01
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved