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《Anhui Medical and Pharmaceutical Journal》 2006-12
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Determination of chlorphenamine maleate and diclofenac sodium in compound diclofenac sodium chlorphenamine maleate tablets by HPLC

ZHONG Huai-bin,SUN Ling-yun,YING Ying(Anhui Provincial Institute for Drug Control,Hefei 230051,China)  
Aim To establish the method for determination of chlorphenamine maleate and diclofenac sodium in compound diclofenac sodium chlorphenamine maleate tablets by HPLC.Methods ODS-C_1_8 column(250 nm×4.6 mm)was used,the detection wavelength at 262 nm,1-Heptanesulfonic acid Sodium solution-methanol-acetonitrile(25∶30∶18)as the mobile phase.Results The calibration curvers were linear in the range of 100.8~ 504.0 mg·L~(-1) for chlorphenamine maleate(r=0.9999) and 16.63~83.15 mg·L~(-1)for diclofenac Sodium(r=0.9997).The average recovery was 100.7% and 98.8% respectively.Conclusions The method is simple,accurate,and well reproducible.It can be used for content determination of chlorphenamine maleate and diclofenac sodium in compound diclofenac sodium chlorphenamine maleate tablets.
【Key Words】: HPLC chlorphenamine maleate diclofenac sodium
【CateGory Index】: R927
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【Citations】
Chinese Journal Full-text Database 1 Hits
1 Ji Yu(Jiangsu Institute for Drug Control,Nanjing,210008);Peak Identification of Chlorphenamine Maleate in HPLC Chromatogram[J];Drug Stanoaros of China;2004-01
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 LV Hai-hua,CHEN Jun(Ningbo Institude for Drug Control,Ningbo Zhejiang,315040);Simultaneous determination of moroxydine hydrochloride,paracetamol,chlorphenamine maleate in ganmaoqing capsule by HPLC[J];Anhui Medical and Pharmaceutical Journal;2007-08
2 Chen Naijiang,Wang Tongkang,Zhang Hong Lianyungang Institute for Drug Control,Jiangsu Rrovince (222006),China;Quantitative Determination of Chlorphenamine Maleate in Biyankang Tablets by HPLC[J];Journal of Zhejiang University of Traditional Chinese Medicine;2010-04
3 ZHANG Li-e1,ZHUGE Zhong-Xi2(1.The Second Hospital Attached to Wenzhou Medical College,Zhejiang Wenzhou 325000,China;2.ZheJiang Conler Pharmaceutical Co.LTD.,Zhejiang Wenzhou 325000,China);Content assaying and the uniformity determination of chlorphenamine maleate in child paracetamol,artificial cow-bezoar and chlorphenamine maleate granules[J];Journal of Pediatric Pharmacy;2007-06
4 LI Guo-cheng,LIU Chun-xia,YU Xiao-xia,LIN Xiao-shan.Depart-ment of Pharmacy,the second affiliated hospital,SUN YAT-SET university,Guangzhou,510120China;Determination of Naphazoline Hydrochloride and Chlorphenamine Maleateide in rhinitis nasal drops by HPLC[J];International Medicine & Health Guidance News;2010-02
5 MA Kun-fang~1,DU Shu-hu~1,WANG De-wang~2,JI Hong-jian~1(1.Pharmaceutical College of Nanjing Medical University,Nanjing 210029,China;2.Department of Pharmacy,The First Pepole's Hospital of Jiangsu Province,Nanjing 210029,China);Determination of Content and Uniformity of Chlorphenamine Maleate in Ganteling Capsules by HPLC[J];Research and Practice of Chinese Medicines;2005-05
6 LI Guo-cheng,LIU Chun-xia,YU Xiao-xia (Department of Pharmacy,Sun Yat-set Memorial Hospital of Sun Yat-set University,Guangzhou,Guangdong 510120,China);Study on Quality Standards of Compound Naphazoline Eye Drops[J];Pharmacy Today;2011-03
7 Tian Hong-gen,Wang Hong-ming(Binzhou Institute for Drug Control, Shandong Binzhou, 256618);Determination of Content and Content Uniformity of Dosage Units of Chlorphenamine Maleate in Compound Paracetamol and Amantadine Hydrochloride Tablets by HPLC[J];Drug Standards of China;2008-03
8 Jin Xiaoqiu,Chen Li(1.School of Pharmacy,Jiangsu University Zhenjiang,China 212001;2.Zhenjiang Institute for Drug Control,Zhenjiang,Jiangsu,China 212003);Determination of Content and Uniformity of Chlorphenamine Maleate in Anchuan Capsules by HPLC[J];China Pharmaceuticals;2008-12
9 Zheng Ali,Gai Ke1 and Qi Huili1(Qingyang City Institute for Drug Control,Gansu Province,Qingyang 745000; 1Gansu Provincial Longdong Institute of Chemistry and Chemical Engineering Institute);Improvement of Method of Identifying Artificial Bezoar in the Compound Preparation[J];Chinese Pharmaceutical Affairs;2008-07
10 Zhan Jianfeng1,2,4,Zhang Yan3 and Huang Haiwei2(1Yueyang Institute for Drug Control,Hunan Province,Yueyang 414000; 2Chinese Pharmaceutical University;3Xiangtan Institute for Drug Control;4 National Institute for the Control of Pharmaceutical and Biological Products);Determination of Bergenin and Chlorphenamine Maleate in Tabellae Bergenin Compositae by Ion Pair Chromatography[J];Chinese Pharmaceutical Affairs;2009-08
【Secondary Citations】
Chinese Journal Full-text Database 9 Hits
1 Wang Yong(Fujian Institute for Drug Control, Fuzhou, 350001);Simultaneous Determination of 5-Component Contents in Kuaian Anticold Solution by High Performance Liquid Chromatography[J];Chinese Journal of Chromatography;1999-03
2 CHEN Zhu ling, ZHANG Lan, WANG Min, HUANG Ying (Department of Chemistry,Fuzhou University, Fuzhou 350002, China);Simultaneous Determination of Chlorpheniramine, Paracetamol and Pseudo-ephedrine Hydrochloride in Composite Tablets by High Performance Liquid Chromatography[J];Chinese Journal of Chromatography;2001-03
3 Wang Yong and Feng Guokang(Fujian Institute for Drug Control, Fuzhou, 350001)Tang Genyuan and Wu Hongjing(Fujian Institute of Research on Structure of Matter, the Chinese Academy of Sciences, Fuzhou, 350002);Determination of Chlorpheniramine Maleate, Acetaminophen,DL-Methylephedrine HCl and Caffeine in Relecold Capsules by High Performance Liquid Chromatography (HPLC)[J];CHINESE JOURNAL OF CHROMATOGRAPHY;1996-04
4 Wei Wanfeng,Wang Wei,Li Guangyao Hainan Sanye Medicine Research Institute,Haikou 570226;HPLC Determination of the Content of Paracetamol,Pseudoephedrine Hydrochloride and Chlorphenamine Maleate in Pseudoephedrine Hydrochloride Compound Tablets[J];JOURNAL OF SHENYANG PHARMACEUTICAL UNIVERSITY;1999-03
5 Jiang Hong(Jiang H),Peng Jun(Peng J),Gao Yingjie(Gao YJ)(General Hospital of Tianjin Medical University,Tianjing 300052);Assay acetaminophen compound caplets tablets by HPLC[J];CHINESE JOURNAL OF MODERN APPLIED PHARMACY;1999-03
6 Ji Yu(Jiangsu Institute for Drug Control,Nanjing,210008);Peak Identification of Chlorphenamine Maleate in HPLC Chromatogram[J];Drug Stanoaros of China;2004-01
7 Hu Yuzhu; Han Nanyin; Lai Yuhong and Ni Kunyi(China Pharmaceutical University, Nanjing. 210009);Application of New Searching Approach for Selectivity Optimization of Mobile Phase System in RP-HPLC for Composite Ganmaoling Tablets[J];CHINESE JOURNAL OF PHARMACEUTICAL ANALYSIS;1995-01
8 Zhai Huimin (Zhai HM), Zhang Xiuzhi (Zhang XZ), Liu Haijing (Liu HJ) (Shanxi Institute for Drug Control, Xi'an 710061);HPLC determination of 3 components in compound of paracetamol, pseudoephedrine hydorochloride and chlorphenamine maleate tablets for children and uniformity of content[J];CHINESE PHARMACEUTICAL JOURNAL;1997-12
9 LI Hui,DING Shui-Ping,FENG Guang (Tongji Hospital a ffliated to Tongji Medical College of Huazhong University of Science and Technology,Hubei W uhan 430030);Determination of three components in Shuangpuweima capsule by HPLC[J];Chinese Journal of Hospital Pharmacy;2001-06
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