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《Anhui Medical and Pharmaceutical Journal》 2009-03
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Protective effects of TFE on experimental cerebral ischemia in rats

YANG Juan,XU Li,FANG Tai-hui(Nanjing University of TCM,Nanjing,Jiangsu 210029)  
Aim To explore the protective effects of total flavons of epimedium(TFE) in experimental cerebral ischemia mice.Methods Rat models of middle cerebral artery occlusion(MCAO) were applied to observe the effect of TFE.Results TFE decreased the neurological deficit scores and cerebral water content in rats,increased superoxide dismutase(SOD) and nitric oxide synthase(NOS) in ischemic brain,and decreased the content of malondiadehyde(MDA).Conclusion TFE obviously improves the symptoms of cerebral ischemia and neurological deficit and decrease the cerebral edema.
【Key Words】： TFE focal cerebral ischemia in rats SOD MDA NOS
【CateGory Index】： R285.5
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