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《Anhui Medical and Pharmaceutical Journal》 2015-10
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Effect of sevoflurane on lungs oxygenation function in patients undergoing one-lung ventilation

MA Jun;HUANG Xiang;KANG Fang;Department of Anesthesiology,Anhui Provincial Hospital Affiliated to Anhui Medical University;  
Objective To investigate the effect of sevoflurane on lung oxygenation functions in patients undergoing one-lung ventilation( OLV). Methods Sixty patients undergoing esophagus surgery with OLV were randomly assigned to Group S and Group P. Propofol,sufentanyl and rocuronium were administered for induction in both groups. Left- or right-sided double-lumen endobronchial tubes were inserted for OLV. Maintenance anesthesia was performed with sevofluarane in Group S,and propofol in Group P. Remifentanil and vencuronium were used in both groups. In addition,ventilation machine was set at the same way in both groups. Heart rate( HR),oxygen saturation( SPO_2),mean arterial pressure( MAP),tidal volumes( VT),airway peak pressure( Ppeak) were recorded before anesthesia( T_1); 15 min after double-lung-ventilation( T_2); 15 min( T_3),30 min( T_4),60 min( T_5) after OLV and 15 min( T6) after reventilation of the deflated lung. Lung dynamic compliance( Cdyn) and oxygen index( OI) were calculated. Arterial blood gas analysis was performed at T_2,T_5,T_6. The clinical outcome was investigated. Results There were no differences in HR,SPO2,MAP,Ppeak,Cdynbetween groups.Compared with group P,Pa O_2 and OI in group S had increased at T_5; the postoperative dyspnea in group S was better than that in group P. Conclusion Sevoflurane improves lung oxygenation during OLV and postoperative dyspnea,possibly due to refraining in the level of NF-κB.
【Fund】: 安徽医科大学校科研基金项目(No 2012XKJ045)
【CateGory Index】: R614
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【References】
Chinese Journal Full-text Database 1 Hits
1 HU Jingchun;QIAN Lijun;LEI Lipei;WU Wei;ZHENG Wangfu;WANG Wu;Department of Anesthesiology,Lishui Central Hospital in Zhejiang Province;Department of Pediatrics,Lishui Central Hospital in Zhejiang Province;;Clinical effect observation on application of sevoflurane general anesthesia in the treatment of sepsis patients[J];中国现代医生;2018-02
【Citations】
Chinese Journal Full-text Database 5 Hits
1 WANG Dong-xin;HOU Wen-jie;DIAO Shi-qi;KAN Hong-li;Department of Anesthesiology,Jilin Province Tumor Hospital;;Effect of sevoflurane preconditioning on inflammatory cytokines and oxygen radicals during one lung ventilation in patients with lung cancer[J];临床麻醉学杂志;2013-09
2 WEI Lei~*,WANG Hui,ZHAO Jian-hua, FANG Zhi-yuan.*Laboratory of Anesthesiology & Institute of Anesthesiology of Jiangsu Province,Xuzhou Medical College,Xuzhou 221002,China;Effects of preconditioning with different concentrations of sevoflurane on the expression of Toll-like receptor 4 in rats with acute lung injury induced by lipopolysaccharide[J];中华麻醉学杂志;2012-08
3 Wu Qianzhi,Ni Chenchen,Zhang Zhihong(Dept of Pulmonary,The Geriatric Institute,The First Affiliated Hospital of Anhui Medical University,Hefei 230022);The study of ventilator induced lung injury in mice[J];安徽医科大学学报;2012-07
4 Jin Jingxing,Li Yuanhai,Chen Ke,et al(Dept of Anesthesiology,The First Affiliated Hospital of Anhui Medical University,Hefei 230022);The protective effect of sevoflurane on lung injury induced by one-lung ventilation and its mechanism[J];安徽医科大学学报;2012-04
5 ZHAO Shuangping,WU Jiao,GUO Qulian,ZHANG Zhong,YE Zhi(Intensive Care Unit,Xiangya Hospital,Central South University,Changsha 410008,China);Effect of different concentrations of sevoflurane pretreatment on acute lung injury induced by endotoxin in rats[J];中南大学学报(医学版);2010-09
【Co-citations】
Chinese Journal Full-text Database 8 Hits
1 LIANG Haofeng;QIN Shaojian;SHI Yan;Anesthesiology Department of the Fourth People's Hospital of Nanning;;Effect of propofol and sevoflurane on pulmonary shunt and oxygenation in patients with pulmonary tuberculosis[J];中国医药科学;2018-08
2 LIU Xiaoguo;XIA Xingui;YANG Shizhong;CHEN Yanqin;Department of Anesthesiology, Zhejiang PAP Corps Jiaxing Hospital;;Effect of sevoflurane combined with sufentanil on the perioperative inflammatory factors in the patients undergoing lumbar spine internal fixation[J];中国现代医生;2018-03
3 Jia Zhongshen;Jiang Zhi;Li Anjie;Wu Yueting;Wei Fang;Department of Cardiology,the Affiliated People′s Hospital of Guizhou Medical University;;Preparation of myocardial ischemia/reperfusion injury model by overlapping line in mice[J];重庆医学;2017-32
4 Shun-fu Chen;Lei Chen;Gang Ye;Department of Anesthesiology, the People's Hospital;;Effect of Dexmedetomidine on inflammatory mediators in thoracoscopic radical resection of lung cancer[J];中国内镜杂志;2017-10
5 Tang Xing-song;He Ming-xue;Dazhou Hospital of integrated Traditional and Western Medicine;;The prevention effect of different one-lung ventilation time on acute respiratory failure after esophageal cancer operation[J];湖南师范大学学报(医学版);2017-04
6 ZHAO Li-qin;ZHANG Hai-long;Department of Anesthesiology,Beijing Ditan Hospital,Capital Medical University;Department of Anesthesiology,Beijing Luhe Hospital,Capital Medical University;;Effect of sevoflurane preconditioning on kidney injury in patients undergoing resection for liver cancer[J];中国医刊;2017-08
7 Ke Min;Lin Wei;Zeng Shenbao;Xie Dechen;Department of Anesthesiology,Fuzhou Pulmonary Hospital;;Effects of inhalation of sevoflurane at different time on pulmonary function and oxidative stress in patients with one lung ventilation[J];中国基层医药;2017-14
8 Lyu Jieping;Tian Shouyuan;Nie Lixia;Hao Qian;Zhou Li;Department of Anesthesiology,the First Hospital of Shanxi Medical University;;The effects of sevoflurane on pulmonary inflammatory response in patients undergoing cardiac surgery with extracorporeal circulation[J];中国医师进修杂志;2017-06
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 Ke Min;Lin Wei;Zeng Shenbao;Xie Dechen;Department of Anesthesiology,Fuzhou Pulmonary Hospital;;Effects of inhalation of sevoflurane at different time on pulmonary function and oxidative stress in patients with one lung ventilation[J];中国基层医药;2017-14
2 WANG Chang-yuan;CAO Tao;SUN Chang-yi;QIN Jian;Department of Emergency,Xuanwu Hospital of Capital Medical University;;Value of procalcitonin to assessing the prognosis of elderly patients with septic shock[J];中华实用诊断与治疗杂志;2016-01
3 MA Jun;HUANG Xiang;KANG Fang;Department of Anesthesiology,Anhui Provincial Hospital Affiliated to Anhui Medical University;;Effect of sevoflurane on lungs oxygenation function in patients undergoing one-lung ventilation[J];安徽医药;2015-10
4 Mai Zhenhua;Tong Lin;Zhong Xiuming;Affiliated Hospital of Guangdong Medical College;;Relationship between the Severity of Kidney Damage and the Levels of Ang-1 and Ang-2 in Patient with Sepsis[J];四川医学;2014-07
5 HUANG Ping;ZHOU Ying;ZHANG Jie;WANG Shanjuan;HANG Yannan;Department of Anesthesiology,Renji Hospital,Shanghai Jiaotong University School of Medicine;;Comparison of the effects of propofol target-controlled infusion and sevoflurane inhalation on hemodynamics during anesthesia induction in elderly patients[J];上海医学;2014-06
6 LI Hongbao;HE Jianguo;Department of Anesthesiology,the Affiliated Hospital of Medical College of Ningbo University;Department of Anesthesiology,Ningbo First Hospital;;Comparison of hepatic and renal function between inhalation anesthesia with sevoflurane and total intravenous anesthesia with propofol for geriatric patients[J];中国现代医生;2014-15
7 CHEN Qiu-ping;FENG Yong-min;ZHANG Yuan-li;YAO Hua-guo;DENG Lie-hua;HE Hui-juan;Affiliated Hospital of Guangdong Medical College;;Analysis of plasma angiopoietin-2,(1,3)-β-D glucan levels and their correlation in septic patients[J];山东医药;2014-08
8 WANG Le~*,ZHAO Jian-hua,LUAN Heng-fei,FANG Zhi-yuan,ZENG Yin-ming.~*The Key Anesthesiology Laboratory of Jiangsu Province,Jiangsu Institute of Anesthesiology,Xuzhou,Jiangsu 221002,China;The mechanism of sevoflurane on the apoptosis of pulmonary cells in rats with acute lung injury induced by lipopolysaccharide[J];国际麻醉学与复苏杂志;2011-02
9 YANG Fen,FANG Zhi-yuan(Jiangsu Province Key Laboratory of Anesthesiology,Xuzhou Medical College,Xuzhou Jiangsu 221002,China);Effects of sevoflurane postconditioning on lungs of rats with lipopolysaccharide-induced acute lung injury[J];江苏大学学报(医学版);2010-03
10 JIN Yan-wu,ZHAO Xin,FENG Hao, WANG Zhi-gang,WANG Duan-yu.Department of Anesthesiology,Second Hospital of Shandong University,Ji'nan 250033,China;Effects of sevoflurane versus propofol anesthesia on inflammatory response and pulmonary function during perioperative period in patients undergoing lung cancer resection[J];中华麻醉学杂志;2010-04
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 JIN Wen-jie, HUA Fu-zhou, WANG Can-qin, GUO Rui, PAN Yin-bing.Department of Anesthesiology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China;Effects of sevoflurane preconditioning on hepatic ischemic reperfusion injury and PI3K/Akt signaling pathway in rats[J];临床麻醉学杂志;2012-08
2 Jin Jingxing,Li Yuanhai,Chen Ke,et al(Dept of Anesthesiology,The First Affiliated Hospital of Anhui Medical University,Hefei 230022);The protective effect of sevoflurane on lung injury induced by one-lung ventilation and its mechanism[J];安徽医科大学学报;2012-04
3 XIAO Yan-ying,CHANG Ye-tian,RAN Ke,et al.Department of Anesthesiology,Xiangya Second Hospital,Center South University,Changsha 410011,China;Role of mitochondrial ATP sensitive potassium channel in delayed preconditioning with sevoflurane reducing myocardial ischemia-reperfusion injury in rats[J];临床麻醉学杂志;2011-03
4 CHAI Jun,LONG Bo,CHEN Wei-min,SHEN Jie(Department of Anesthesiology,Shengjing Hospital of China Medical University,Shenyang,Liaoning 110004,P.R.China);Effect of sevoflurane on tissue permeability of ischemia-reperfusion lungs[J];中国现代医学杂志;2010-17
5 ZHAO Shuangping,WU Jiao,GUO Qulian,ZHANG Zhong,YE Zhi(Intensive Care Unit,Xiangya Hospital,Central South University,Changsha 410008,China);Effect of different concentrations of sevoflurane pretreatment on acute lung injury induced by endotoxin in rats[J];中南大学学报(医学版);2010-09
6 GUO Zhengming1,CHEN Yi2,LIU Huijun2,XIAO Yuequn1,SONG Haipeng1,WANG Zhaozhao1,QU Xiaolin1,LUO Ziqiang2(1.Department of Basic Science,Hunan Traditional Chinese Medicine College,Zhuzhou Hunan 412012;2.Department of Physiology,Xiangya School of Medicine,Central South University,Changsha 410078,China);Ginkgo biloba extract (Ginaton) attenuates acute lung injury induced by lipopolysaccharide in mice[J];国际病理科学与临床杂志;2009-04
7 LIN Wen-qian,LU Xiao-yun, CAO Long-hui, et al.Department of Anesthesiology, Cancer Center of Sun Yat-sen University and State Key Laboratory of Oncology of South China,Guangzhou 510060, China;Effects of lung protective ventilatory strategy on inflammatory responses in patients with abnormal lung function undergoing esophagectomy[J];临床麻醉学杂志;2008-08
8 CHANG Jia-song,WEI Kai-feng,XU De-guo(Nanjing University of Chinese Medicine,Nanjing 210029,Jiangsu,China);Effect of Shengjiang Powder on Expression of ICAM-1 of Lung Tissue Cells in Acute Lung Injury Rats[J];辽宁中医药大学学报;2008-01
9 YOU Zhi-jian, YAO Shang-long,LIANG Hua-gen. Department of Anesthesiology, Xiehe Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022,China;Comparison of lung injury degrees after one-lung ventilation for different time[J];中国急救医学;2007-02
10 SUN Yan-hong (?) Yong WANG Jun-ke Department of Anes(?)siology,Frist Affi(?) (?) of (?) Medical University,Shenyang 110001,China;Effects of sevoflurane on endotoxin-induced oxidative stress response of the lungs in rats[J];中华麻醉学杂志;2006-08
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