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《Journal of Anhui Traditional Chinese Medical College》 1996-03
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Nitric Oxide Participates in Protec rive Effects of Acupuncture on Gastric Mucosal Damages in Rats

Xu Guansun  
The rnucosal lesion index, gastric mueosal blood flow(GMBF), gastric electric activity(GEA), con-tents of NO synthase in mueosal and NO in serum were studied on a rat model of restraint cold stress-inducded gastric mu-cosal damage. Meanwhile, the protective effect of etectroacupuncture (EA) on the gastric mucosal were observed, It was found that the relationship between decrease of GMBF, GEA, gastric mucosal level of NOS, serum level of NO and stress-induced gastric mucosal damage in rats were closely existed. EA (pre-stress or post-stre~s) could effcctly protect the gastric mucosal damage and increase of previous quota. The mechanism of protective effect of EA on gastric mucosal was discussed. We speculate that EA agitalcs that synthesis and release of NO in intestinal nerve system, NO mediates the in-tegrity of gastric mucosal, NO participates in protective effect of EA on gastric mucosal damage.
【Fund】: 国家攀登计划项目资助(JL-93012)
【CateGory Index】: R245
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