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EFFECTS OF QIONGYUGAO ON THE EXPRESSION OF NM23 AND PCNA OF EXPERIMENTAL LUNG CANCER MICE TREATED BY CHEMOTHERAPY

Chen Xiaoyin,Shen Zhuoqun (Departmant of TCM,Medical College of Jin'an University,Guangzhou 510632,China)  
Objective:To elucidate the effects of Qiongyugao on the expression of PCNA and nm23 of experimental lung cancer mice treated by chemotherapy.Method:cells culture,making model by transplanting cancer cells,immunohistochemistry.Result:We find chemotherapy can suppress the protein expression of PCNA,and Qiongyugao may enhance this effect,chemotherapy can promote the protein expression of nm23,and Qiongyugao may enhance the effect.Conclusion:Qiongyugao may improve the effects of chemotherapy by inhibiting tumor metastasis and cells'division.
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