Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
Add to Favorite Get Latest Update


Wang Zhijie,Huang Tieniu (Virus Research Institute,Hubei Medical University,Wuhan 430071,China)  
Objective:In order to obtain the most excellent dispensing proportion of Chinese medicinal herbs,we carry out this research.Method:we use ACV as positive control,observe antiherpes effects on HSV -2 333 strain of rhizoma polygoni cuspidati and astragalus membranaceus which are used lonely or in combination byplaque reduction assay,and make effect analysis of combination by median effect principle.Result:In HEp -2 cell system,the ED 50 s of the direct virucidal activity,the inhibition effects on the multiplication and infection of HSV -2 333 strain of ACV are 16.45,10.85 and 18.12μg/ml respectively.When combination ratio of rhizoma polygoni cuspidati/astragalus membranaceus equals 1(ED 50 ) of the former/1(ED 50 ) of the latter,the corresponding figures are 2.27,2.04 and 1.32μg/ml separately.Comparing with ACV,the effects is stronger than ACV,and the average combination index is the smallest,there is the most significant synergism.Conclusion:The treatment indices(TI) of the direct virucidal activity,the inhibition effects on the multiplication and infection of HSV -2 333 strain of this combination ratio are 726,525,1 400 times of ACV TIs respectively,it is the most excellent combination ratio.
【Fund】: 湖北省自然科学基金!(No .980J0 90 )
【CateGory Index】: R285.5
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 3 Hits
1 Wang Zhijie,Huang Tieniu,Liu Yanwen Medical College of Wuhan University,Wuhan(430071);Pharmadynamics Analysis to Emodin in Rhizoma Polygoin Cuspidati and Total Saponins in the Root of Astragalus Membranaceus Used on Anti Herpus Virus[J];Journal of Zhejiang College of Tcm;2003-01
2 Wang Zhijie,Huang Qishan Virus Institute of Medical College in Wuhan University (430071);Pharmacodynamic Analysis on Resisting Type Ⅱ Human Herpes Virus with Resveratrol and Total Astragalin[J];Journal of Zhejiang College of Tcm;2005-06
3 WANG Zhi jie 1,HUANG Tie niu 2,LIU Yan wen 3 (1.Virus Research Institute of Medical College of Wuhan University, Hubei Wuhan 430071, China; 2.Zhongnan University of Economics and Law,Hubei Wuhan 430064,China; 3.Departement of Chinese Materia Medi;The Effect Analysis of Antiherpes Simplex Virus Type-2 333 Strain with Combination of Emodin of Rhizoma Polygoni Cuspidati and Total Polysaccharides in The Root of Astragalus Membranacues[J];China Journal of Basic Medicine In Traditional Chinese Medicine;2002-05
Chinese Journal Full-text Database 10 Hits
1 SHAN Bao-en1, REN Feng-zhi2, LIANG Wen-jie1,3,ZHANG Jing1,Li Qiao-xia1, ZENG Ya-ping4(1.Research Center, the Fourth Hospital of Hebei Medical University, Shijiazhuang, 050011,China;2.North China Pharmacal Coperation China;3.Hebei Medical University Shijiazhuang 050011,China;4.Hebei Science and Technology Publishing House,Shijiazhuang,050073, China );Isolation and Purification of Antitumor Component in Rhizoma Menispermi and Analysis of Its Activity[J];Carcinogenesis,Teratogenesis & Mutagenesis;2006-03
2 ZHU Jing-tong,BAI Yu ,SI Wen-xiu ,LIU Hong-xi,REN Qu-hui (NCPC Drug R&D Co,Ltd,Shijiazhuang 050015,China);Study About Anti-tumor Effect of Pulsatilla Chinensis(Bunge)Regel Extracts in Vitro[J];Carcinogenesis,Teratogenesis & Mutagenesis;2007-01
3 Wu Jinlong, Wang Liyun, Lin BoayinJiangsu provincial Anti─Epidemic and Hygienic Station, Nanjing 210009;GENOTOXIC EFFECT OF CDOP ON GERM CELL OF MALEMOUSE[J];CARCINOGENESIS, TERATOGENESIS AND MUTAGENESIS;1994-03
4 Wu Jinling; Shi Genyong; Chcn Xinxia and Wang Liyun(Jiangsu Provincial Anti-Epidemic and Hygienic Station,Nanjing 210009);MUTAGENICANDANTIMUTAGENICDETECTIONOFSODIUMBISELENITEINVITRO[J];CARCINOGENESIS, TERATOGENESIS AND MUTAGENESIS;1996-02
5 WANG Zhi jie,HUANG Tie niu,LIU Yan wen,YANG Zhan qiu,XIAO Hong (Virology Institute, Medical College, Wuhan University, Hubei Wuhan 430071, China);ANTI-VIRAL EFFECTS OF TOTAL POLYSACCHARIDES OF ASTRAGALUS MEMBRANACEUS ON HERPES SIMPLEX VIRUS TYPE-2[J];Journal of Anhui Traditional Chinese Medical College;2002-02
6 LI Chun yi1,REN Wen long2,LI Chang ben3,et al.1.Department of Clinical Pharmjacology,Beijing Institute for Cancer Research, Beijing 100034,P.R.China2.Department of Pharmacology,Shanghai Institute of Pharmaceutical Industry,Shanghai 200437,P.R.China3.Th;The antitumor activity of recombinant human lymphotoxin[J];CHINESE JOURNAL OF CANCER;1999-04
7 PENG Xu yang, HE Zhi ding, WU Yang Hunan Province Tumor Hospital, Changsha 410006,P.R.China;Induction of apoptosis in human colorectal carcinoma cell line SW 260 by THP[J];CHINESE JOURNAL OF CANCER;1999-06
8 LI Ping*, ZHENG Jian, GUO Liang- jun, ZHUANG Cheng- hai Department of Oncology, the First Affiliated Hospital, Jinan University, Medical College, Guangzhou 510630, P.R.China;Concomitant Cisplatin and 5- Fluorouracil with Veinal or with Oral High- Dose Leucovorin in Treatment of Patients with Advanced Nasopharygeal Carcinoma[J];Chinese Journal of Cancer;2001-04
9 TANG Cheng wei*, TANG Li ping, WANG Chun huiDepartment of Gastroenterology,The First Hospital,Chongqing University of Medical Sciences, Chongqing 400016,P.R.China;Effects of Combination of Octreotide and Aspirin on Proliferation ofHuman Hepatocellular Carcinoma[J];Chinese Journal of Cancer;2002-04
10 YANG Jun-xia1*,TANG Wei-xue2 1.Department of Pharmacology,2.Department of Pathophysiology,Chongqing Medical University,Chongqing 400016,P.R.China;Establishment of a Cisplatin-Induced Human Hepatocellular Carcinoma Drug-Resistant Cell Line and Its Bio logical Characteristics[J];Chinese Journal of Cancer;2002-08
Chinese Journal Full-text Database 10 Hits
2 Wang Zhijie Huang Tieniu Liu Yanwen et al Medical College of Wuhan University(430071)△Zhongnan University of Economics and Law;The Experimental Research of Antiherpes Simplex Virus Type-2 Effects of Total Saponins in the Root of Astragalus Membranaceus[J];Journal of Zhejiang College of Tcm;2001-05
3 Zhu Zuojiang et al ( Department of Pathophysiology );The improvement of microcirculation in rat with irreversible hemorrhagic shock by crystal No 4 of polygonum cuspidatum[J];Journal of First Military Medical University;1987-02
4 Luo Sufang, Zhang Peiwen,Li Ruisong Department of Pharmacology, First Military Medical University;Dilating action of 3 , 4', 5 - trihydroxystibene - 3 -β -mono-D-glucoside on rabbit' s blood vessels[J];Journal of First Military Medical University;1992-01
5 ZENG Li 1,2, LIAN Chun -xia 2, XIA Zhi -ning 2 (1.Chongqing Medical Staff College, Chongqing 400050,China; 2.College of Chemistry and Chemical Engineering, Chongqing University, Chongqing 400044,China);Extracting Resveratrol from the Polygonum Cuspidatum Sieb under Ultrasonic Wave and Its Analysis by High Performance Liquid Chromatography[J];Journal of Chongqing University(Natural Science Edition);2002-07
6 Zhang Changsheng,Zeng Zhiliang,Li Li Wuhan NO.1 Hospital(430022);Experimental Report of Four-kind Pathogenic Fungi Inhibited by Compound Huzhang Solution[J];JOUNAL OF HUBEI COLLEGE OF TRDITIONAL CHINESE MEDICINE;2000-02
7 Qian Jihong, Ao Liming, Chen Guanyi, Wu Shengmei. Department of Pediatrics, Xinhua Children's Hospital affiliated to Shanghai Second Medical U-niversity, Shanghai 200092;Short-term follow-up of congenital asymptomatic HSV-Ⅱinfection in newborn infants[J];The Journal of clinical Pediatrics;2001-03
8 CHEN Lei1, YANG Fu _ quan2, ZHANG Tian _ you2, HAN Ya _ shan1, CHEN Shang _ wu1(1. China Agricultural University, Beijing 100094, China;2. Beijing Institute of New Technology Application, Beijing 100035, China);Separation and Analysis of Resveratrol and Piceid in Polygonum Cuspidatum Sieb. et Zicc.[J];JOURNAL OF INSTRUMENTAL ANALYSIS;2000-04
9 Tang Wangxian, Yu Dixia, Dan Zili et al Institute of Liver Diseases, Tongji Hospital, Tongji Medical Unviersity, Wuhan 430030 Department of Liver Diseases, Wuhan No. 7 Hospital, Wuhan 430071;Study on Protective Effect of Traditional Chinese Herbs (Ganyanping) on Acute Liver Injury Induced by D-GalN in Rats[J];Journal of Tongji Medical University;1998-01
10 Huang Qiaobing; Zhao Kesen;Huang Xuliang(First Military Medical University Chinese PLA,Guangzhou 510515);Effects of Crytal No4 of Polygonum Cuspidatum, Dopamine and 645-2 on Hemorrhagic Shock in Rats[J];CHINESE JOURNAL OF MICROCIRCULATION;1995-01
【Secondary References】
Chinese Journal Full-text Database 4 Hits
1 Ma Yongyong Department of Hemotology,The First Affliated Hospital of Wenzhou Medical College (325027),China;The Effects of Res on Expression and Secretion of IL-8 and VEGF of Lymphoma Raji Cells[J];Journal of Zhejiang University of Traditional Chinese Medicine;2008-06
2 Rui Wen, Cen Yyingzhou, Xing Yingying, Su Miaoxian(Jinan university, Guangzhou 510632,China);Research on the Antihepatitis Herbal Medicine of Yao Nationality[J];Guangdong Chemical Industry;2005-03
3 LI Sheng-hua,WU Xian-jin (Department Bioengineering of Huaihua College, Huaihua 418008,China);Study on extraction processing of resveratrol from Polygotnum cuspidatum by supersonic extraction[J];Science and Technology of Food Industry;2008-07
4 SONG Zhen-guo1,WEI Shi-chao1,FENG Yao1,LU Fu-er2(1.Department of Pharmacy;2.Institute of Combination of TCM with Western Medicine,Tongji Hospital Affiliated with the Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China);Studies on the Technique of the Alcoholic Extraction of Ganzhixiao Capsule[J];Herald of Medicine;2008-04
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved