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《Journal of Anhui Traditional Chinese Medical College》 2001-04
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MAGNIFYING EFFECT OF MICRO-INJECTION OF VASOACTIVE INTESTINAL PEPTIDE INTO DORSAL MOTOR NUCLEUS OF VAGUS COMPLEX ON GASTRIC MUCOSA BLOOD FLOW AND MODULATIONEFFECT OF ELECTRIC ACUPUNCTURE IN RATS

YANG Yong-xing,XU Guan-sun,SHEN De-kai,ZHU Qing-feng,LIU Yong,ZHANG Dao-qin (Institute of Acupuncture and Meridians,Anhui College of TCM,Anhui Hefei 230038,China)  
Objective:To investigate the changes of gastric mucosal blood flow(GMBF)and regulative effect of electro-acupuncture on GMBF in rats with micro-injection of vasoactive intestinal peptide(VIP) into dorsal motor nucleus of vagus complex(DVC).Method:The neurocentre of rat was located and injected by the stereotaxic apparatus of the rat brain,electro-acupuncture (EA)of Zusanli(ST-36) points was applied.GMBF was measured by the method of hydric gas clearance;The contents of VIP in the serum was assayed by radioimmunoassay.Result:The contents of VIP in the serum,transmucosal potential difference(PD) and GMBF were all increased(P0.01) after micro-injection of VIP into DVC.These effects were enhanced by EA at Zusanli(ST-36) points.Conclusion:The magnifying effect on GMBF is induced by micro-injection of VIP into DVC,VIP is a strong neuropeptide in nerve endocrine immunity system(NEIS),DVC is a special part of neurocentre influenced by VIP,EA has the synergistic effects on micro-injection of VIP into DVC.
【Fund】: 安徽省自然科学基金资助项目 (974140 0 7)
【CateGory Index】: R245.97
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