Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Anhui Traditional Chinese Medical College》 2002-02
Add to Favorite Get Latest Update


LIU Jian,HAN Ming xiang,ZHANG Wan dong,CHEN Guang liang,LEI Li (The First Hospital Affiliated to Anhui College of Traditional Chinese Medicine,Anhui Hefei 230031,China)  
Objective:To observe the effects of Xinfeng capsule(XFC) on the levels of interleukin 1(IL 1),tumor necrosis factor α (TNFα), interleukin 4 (IL 4), interleukin 10 (IL 10) of adjuvant arthritis rats. Method: 50 rats were averagely divided into normal control group, model control group, XFC treated group, tripterygium wilfordii polycoride tablet (TPT) treated group, methotrexate (MTX) treated group. Except for the rats of normal control group, the others were intracutaneously injected with 0.05 ml of Freung′s complete adjuvant in the right hindlimb. The serum cytokine levels of each rat were assayed. Result:The arthritis index (AI) of XFC, TPT,MTX treated group was markedly decreased after treatment (P0.05 or P0.01). The increment of rat body weight (BW) in XFC treated group wasn′t significantly different from that of normal control group (P0.05). The increment of rat BW of TPT, MTX treated group was significantly lower than that of XFC treated group, normal control group (P0.01). The IL 1 level of XFC treated group was ob viously decreased in comparison with that of model control group, and IL 4,IL 10 level significantly increased (P0.01). There was no significant difference between the IL 1, TNFα, IL 4,and IL 10 levels of XFC treated group and the other two treatment group (P0.05). Conclusion: The effect of XFC on the decrement of AI is the same as that of TPT, MTX in adjuvant arthritis rats, while effect of XFC on the increment of BW is superior to that of TPT, MTX. XFC decreases AI, eliminates swelling by down regulating the levels of IL 1, TNFα, up regulating the levels of IL 4, IL 10, restraining the inflammatory reaction.
【Fund】: 卫生部优秀青年科研基金项目 (992 6 )
【CateGory Index】: R259.9
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 8 Hits
1 Song Cai-xia(Qing Dao Haicer Yi Liao Ji Tuan,Qingdao 266033 China) Zhou Cui-ying,Fan Bing,Xu Hua(Affiliated Hospital of Shandong Uniyersity of TCM,Jinan 250011,China);Influence of Xinsimiao Decoction Upon Serum Cytokine Levels in Rats with Adjuvant Arthritis[J];Guangming Journal of Chinese Medicine;2007-05
2 LIU Jian (The First Affiliated Hospital, Anhui College of Traditional Chinese Medicine, Anhui Hefei 230031, China);Research on the Treatment of Rheumatoid Arthritis Based on Spleen[J];Journal of Anhui Traditional Chinese Medical College;2004-01
3 LIU Jian,FAN Haixia,YANG Meiyun(The First Hospital Affiliated to Anhui College of Tradittional Chinese Medicine,Hefei 230031,China);Changes of pulmonary function,pulmonary HRCT images and cytokines in adjuvant arthritis rats[J];Chinese Journal of Clinical Healthcare;2006-06
4 ZHU Huai-min,LIU Jian,PAN Yu-zhen,CHEN Rui-lian,HUANG Chuan-bing(Department of Rheumatology,Traditional Chinese Medical Hospital of Anhui Province,Hefei 230031,China);The research on the change and the correlation of red cell parameter,cytokines in Adjuvant Arthritis Rats[J];Chinese Journal of Clinical Healthcare;2009-02
5 LIU Jian,ZONG Rui-Kai,YU Xue-Fang,WANG Yuan.Department of Rheumatology,Traditional Chinese medical hospital of Anhui Province,Hefei 230031,China;The effects of Xinfeng capsule on platelet parameters and serum cytokines in adjuvant arthritis rats[J];Chinese Journal of Immunology;2008-07
6 LIU Jian, FAN Hai-Xia, YANG Mei-Yun. The First Hospital Affiliated to Anhui College of Tradittional Chinese Medicine, Hefei 230031, China;The influence of Xinfeng capsule on pulmanory HRCT images and cytokines in blood serum of adjuvant arthritis rats[J];Chinese Journal of Immunology;2007-03
7 LIU Jian,YANG Mei-yun,and FAN Hai-xia Department of Rheumatology,The First Affiliated Hospital of Anhui College of TCM,Hefei(230031);Changes of Behavior and Brain Amino Acids of Rats with Adjuvant Arthritis and Effects of Xinfeng Capsule on Them[J];Chinese Journal of Integrated Traditional and Western Medicine;2007-05
8 PAN Yu-zhen,LIU Jian,ZHU Huai-min,CHEN Rui-lian(Department of Rheumatology,The First Affiliated Hospital of Anhui College of TCM,Hefei 230031,Anhui,China);The Changes and Effects of Xinfeng Capsule on Apolipoprotein A1,High-density Llipoprotein and BVE Ultramicro-structure in Adjuvant Arthritis Rats[J];Chinese Archives of Traditional Chinese Medicine;2009-04
China Proceedings of conference Full-text Database 3 Hits
1 Liu Jian Zong Ruikai Yu Xuefang (Department of Rheumatology,Traditional Chinese medical hospital of Anhui province,Hefei 230031);The Changes and Effects of Xinfeng Capsule on platelet parameters and cytokines in Adjuvant Arthritis Rats[A];[C];2008
2 Liu Jian YangMeiYun FanHaiXia (Department of Rheumatology,The First Affiliated Hospital of Anhui College of TCM,Hefei,230031);Effects of Xinfeng Capsule on Behaviors and Serum Cortisol and Brain Amino Acids in Adjuvant Arthritis Rats[A];[C];2007
3 LILT Jian FAN Haixia Yang Meiyun (The First Hospital Affiliated to Anhui College of Tradittional Chinese Medicine,Anhui Hefei 230031,China);THE INFLUENCE OF XINFENG CAPSULE ON THE PUMANORY FUNCTION,PULMANORY HRCT IMAGES AND CYTOKINES IN ADJUVANT ARTHRITIS RATS[A];[C];2007
Chinese Journal Full-text Database 2 Hits
2 LIU Jian,HAN Mingxiang,FANG Zhaohui,et al.The First Affiliated Hospital of Anhui TCM College,Hefei Anhui 230031;Study on clinical curative effects of Xinfeng capsule(新风胶囊) on the patients with rheumatoid arthritis[J];Integrated Traditional Chinese and Western Medicine In Practice of Critical Care Medicine;2001-04
Chinese Journal Full-text Database 10 Hits
2 Fang Jianqiao,Kan Fangju Zhejiang College of TCM,Hangzhou(310053);Influences of Electroacupuncture on Pain Threshold and Antiˉcollagen Antibody,ILˉ1βin CIA Rats[J];Journal of Zhejiang College of Tcm;2003-01
3 Fang Jianqiao(方剑乔)Liu Jinhong(刘金洪) Zhao Tianzheng(赵天征)et al Acupuncture-Moxibustion and Massage Department, Zhejiang College of TCM,Hangzhou(310009);Initial Observation about Acupoint Application with Cantharis to Treat Murine Collagen-induced Arthritis[J];JOURNAL OF ZHEJIANG COLLEGE OF TCM;2000-01
4 BAO Yi-Xiao1, ZHANG Lu-Ding1, LI Li2, HAN Lian-Shu1, KONG Xian-Tao2 (1. Department of Pediatrics,Changzheng Hospital,Second Military Medical University,Shanghai 200003, China; 2. Department of Clinical Laboratory,Changzheng Hospital);Effect of tripterine on expression of bcl-2 family, c-myc and ICE gene in HMC-1 cells[J];Academic Journal of Second Military Medical University;2001-09
5 ZHOU You xin*, HUANG Yu lun,XU Qi nian,YE Ming, SUN Cheng fa, ZHOU DaiDepartment of Neurosurgery,The First Affiliated Hospital of Suzhou University,Suzhou,215006,P.R.China;Several Monomes from Tripterygium Wilfordii Inhibit Proliferation of Glioma Cells In Vitro[J];Chinese Journal of Cancer;2002-10
6 LIU Jian, LIU Xiao hui, HAN Ming xiang (The First Hospital Affiliated to Anhui College of Traditional Chinese Medicine, Anhui Hefei 230031, China);Treatment of 20 Cases of Rheumatoid Arthritis in Active Stage with Xinfeng Capsule[J];Journal of Anhui Traditional Chinese Medical College;2003-03
7 Pang XuefengThe Second Affiliated Hospital, Guangxi TCM University 530001 Nanning;Observation of Curative Effect of Modified Decoction of Qinjiao on Rheumatoid Arthritis[J];Guangxi Journal of Traditional Chinese Medicine;2002-01
8 ZHOU Jialing,ZHU Qi.Department of Rheumatology,Shanghai Guanghua Hospital of Integrated Traditional Chinese and Western Medicine,Shanghai 200052, China;Effects of acupuncture on the rheumatoid arthritis[J];CHINESE JOURNAL OF RHEUMATOLOGY;2000-03
9 MA Li,GUO Wan shou,TAO Xue lian,WU Dong hai.Department of Rheumatology,China Japan Friendship Hospital,Beijing 100029,China;Comparition of inhibitory effects between three kinds of drugs on NO production and iNOS activity in human chondrocytes of rheumatoid arthritis patient[J];Chinese Journal of Rheumatology;2003-04
10 TANG Shi jing,YUE Yang sheng,ZHAO Wei hong (The 421th Hospital,PLA,Guangdong Guangzhou 510318,China);53 CASES OF RHEUMATOID ARTHRITIS TREATED WITH QUARTET THERAPY[J];Journal of Anhui Traditional Chinese Medical College;2002-04
【Secondary References】
Chinese Journal Full-text Database 6 Hits
1 TU Sheng-hao,SHENG Dong-yun, XIONG Ri-bo,HU Yong-hong(The Department of Integrated Traditional Chinese and Western Medicine,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Hubei Wuhan 430030,China);The Inhibitory Effect of Triptolide on Interleukin-1β Production by PBMC from RA Patients with the Gene Polymorphisms of Interleukin-1β[J];Journal of Anhui Traditional Chinese Medical College;2006-03
2 TU Sheng-hao, SHENG Dong-yun, CHEN Hong- bo, HU Yong-hong. Department of Integrated Traditional Chinese and Western Medicine, Tongji Hospital,Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China Corresponding author: TU Sheng- hao;The correlation of the inhibitory effect of triptolide on interleukin-1βproduction from peripheral blood mononuclear cells with the gene polymorphisms of interleukin-1β[J];Chinese Journal of Rheumatology;2005-09
3 Gao Peifang Cai Hui;Prospect about Rheumatoid Arthritis' TCM Treatment in Active Stage[J];Guangming Journal of Chinese Medicine;2009-02
4 WANG Shu-dong,FANG Li,LI Han-bao(Department of Pharmaceutical Preparation,Jinling Hospital,Nanjing 210002,Jiangsu,China);Experimental study on the extraction of total triptolides from lactone leaves with macroporous resin[J];Journal of Medical Postgraduates;2009-04
5 SONG Yan,ZHAN Yujian,GU Jihong Department of Ophtyalmology ,the First affiliated Hospital of Guangzhou TCM University ,Guangzhou 510405,China;The study development of uveitis and relative cytokine[J];Journal of Traditional Chinese Ophthalmology;2004-03
6 WANG Zhen-jiang,XIAO Geng-sheng,LIU Xue-ming,et al.Sericulture and Farm Produce Processing Research Institute of Guangdong Academy of Agricultural Sciences(Guangzhou 510610,China);Anti-inflammatory activity of anthocyanins from mulberry on adjuvant-induced arthritis[J];Chinese Journal of Public Health;2009-02
China Proceedings of conference Full-text Database 2 Hits
1 LONG Zheng-hai~1 WEI Deng-ming~2 DU Ji-bin~3 (1.Zhejiang Pharmaceutical College,Ningbo 315100; 2.Medicalcollege of Ningbo University,Ningbo 315211; 3.Zhejiang Quansheng pharm CO.,LTD,Ningbo 315301;Study on Preparation and Quality Control of Triptolide Compound Cream[A];[C];2008
2 WANG Shu-dong LI Han-bao (Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing 210002.Jiangsu.China);Experimental study on extract of the iactone leaves total triptolides with macroporous resin[A];[C];2008
【Secondary Citations】
Chinese Journal Full-text Database 3 Hits
1 Peng Shanyun;Kang Xinju;Ling Shigan;Song Xiaoguo;Wang Jiaxi;Ma Xiankai(Institute of Basic Medical Sciences,Academy of Military Medical Sciences);MTT colorimetric metbod for determination of IL-6 activity and its applications[J];BULLETIN OF THE ACADEMY OF MILITARY MEDICAL SCIENCES;1994-01
2 Zheng Yiwen, Ma Donglai, Chen Minzhu (The Clinical Pharmacology Institute, Anhui Medical University, Hefei 230032);EFFECTS OF LUTEOLIN ON H_2O_2 RELEASE OF PERITONEAL MACROPHAGES IN RAT[J];Chinese Pharmacological Bulletin;1990-01
3 MA Dong-lai,et al.Institute of Clinical Pharmacology,Anhui Medical University,Hefei 230032;The immunoregulatory mechanisms of N-(2-Carboxyphenyl)-4-Chloroanthranilic Acid Disodium(CCA)on treating Adjuvant Arthritis(AA)in rats[J];Chinese Journal of Immunology;1992-02
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved