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《Journal of Anhui Traditional Chinese Medical College》 2006-02
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Sijunzi Decocation May Strengthen the Influences of Thyroxine on Thymus in Rat Model of Spleen-asthenia

LI Gang,LIANG Hong-juan,ZHANG He-long,SU Qin, MIN Jie,XIA Tian,TANG Guang-Liang(Department of Oncology,Tangdu Hospital,Fourth Military Medical University,the Chinese people′s Liberation Army,Shaanxi Xi′an 710038,China)  
Objective: To demonstrate the relationship between Spleen-asthenia syndrome and the interacted net of thymus-neuro-endocrino-net system and to further elucidate the roles of Sijunzi decocation.Method: Rhubarb decoction was used to develop spleen-asthenia syndrome in SD adult rat.Thirty-two rats were averagely divided in to four groups at random.Group A: control group,group B : spleen-asthenia group,group C : treated by sijunzidecoction group,group D :spontaneous rehabilitation group.Thyroxin serum levels,contents of T_3 receptors of given thymus T lymphocytes,serum thymulin levels,ratios of thymus weights to body weights and thymus IL-2 levels were measured in the study.Result: ① In group B and D,rat thyroxin serum levels,contents of T_3 receptors of given thymus T lymphocytes,serum thymulin levels,ratios of thymus weights to body weights and thymus IL-2 levels were all lower than those in group A,C(P0.05,P0.01).②The parameters in group A and C had no significant difference.Conclusion: Sijunzi decocation may strengthen the influences of thyroxin on thymus in rat model of spleen-asthenia.
【Fund】: 国家自然科学基金资助项目(392708643057212530171052)
【CateGory Index】: R285.5
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